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Product Details
PA5-65806
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human ABR. Recombinant protein control fragment (Product #RP-106480).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663211
Product Specific Information
Immunogen sequence: LYSNFSYGTDE YDGEGNEEQK GPPEGSETMP YIDESPTMSP QLSARSQGGG DGVSPTPPEG LAPGVEAGK
Highest antigen sequence identity to the following orthologs - mouse 91%, rat 86%.
Target Information
This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. Functional studies in mice determined that this protein plays a role in vestibular morphogenesis, suggesting that Rho-related GTPases help coordinate motor skills and balance. Alternatively spliced transcript variants that encode different isoforms have been reported for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Active breakpoint cluster region-related protein
Gene Aliases: ABR; MDB
UniProt ID: (Human) Q12979
Entrez Gene ID: (Human) 29
negative regulation of cellular extravasation
small GTPase mediated signal transduction
brain development
actin cytoskeleton organization
response to lipopolysaccharide
regulation of Rho protein signal transduction
inner ear morphogenesis
positive regulation of apoptotic process
regulation of vascular permeability
negative regulation of neutrophil degranulation
positive regulation of GTPase activity
negative regulation of inflammatory response
positive regulation of phagocytosis
neuromuscular process controlling balance
regulation of small GTPase mediated signal transduction
negative regulation of blood vessel remodeling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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