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Product Details
20410-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: KSLGDQYVKD EFRRHKTVGS DEAQRFLQEW EVYATALLQQ ANENRQNSTG KACFGTFLPE EKLNDFRDEQ IGQLQELMQE ATKPNRQFSI SESMKPKF
Target Information
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACN9 homolog; protein ACN9 homolog, mitochondrial; SDH assembly factor 3; Succinate dehydrogenase assembly factor 3, mitochondrial
Gene Aliases: ACN9; DC11; LYRM10; Sdh7; SDHAF3
UniProt ID: (Human) Q9NRP4
Entrez Gene ID: (Human) 57001
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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