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Search Thermo Fisher Scientific
Immunogen sequence: YATALLQQAN ENRQNSTGKA CFGTFLPEEK LNDFRDEQIG QLQELMQEAT KPNRQFSISE SMKP
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 83%.
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACN9 homolog; protein ACN9 homolog, mitochondrial; SDH assembly factor 3; Succinate dehydrogenase assembly factor 3, mitochondrial
Gene Aliases: ACN9; DC11; LYRM10; Sdh7; SDHAF3
UniProt ID: (Human) Q9NRP4
Entrez Gene ID: (Human) 57001
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