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Product Details
PA5-101404
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ACOT8(Accession O14734), corresponding to amino acid residues H117-L167.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2850840
Product Specific Information
Antibody detects endogenous levels of total ACOT8.
Target Information
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. It may mediate Nef-induced down-regulation of CD4. It may be involved in the metabolic regulation of peroxisome proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acyl-CoA thioesterase 8; Acyl-coenzyme A thioesterase 8; choloyl-CoA hydrolase; Choloyl-coenzyme A thioesterase; hACTE-III; HIV-Nef associated acyl-CoA thioesterase; HIV-Nef-associated acyl-CoA thioesterase; long-chain fatty-acyl-CoA hydrolase; Nef (lentivirus myristoylated factor) associated protein 1; palmitoyl-CoA hydrolase; peroxisomal acyl-CoA thioesterase 1; Peroxisomal acyl-CoA thioesterase 2; Peroxisomal acyl-coenzyme A thioester hydrolase 1; Peroxisomal long-chain acyl-CoA thioesterase 1; PTE-1; PTE-2; Thioesterase II; thioesterase III
Gene Aliases: ACOT8; ACTEIII; hACTE-III; HNAACTE; hTE; NAP1; PTE-1; PTE-2; PTE1; PTE2
UniProt ID: (Human) O14734
Entrez Gene ID: (Human) 10005
acetyl-CoA hydrolase activity
receptor binding
protein binding
CoA hydrolase activity
palmitoyl-CoA hydrolase activity
choloyl-CoA hydrolase activity
acyl-CoA hydrolase activity
carboxylic ester hydrolase activity
medium-chain acyl-CoA hydrolase activity
long-chain acyl-CoA hydrolase activity
esterase
acyl-CoA metabolic process
bile acid biosynthetic process
viral process
peroxisome fission
fatty acid beta-oxidation using acyl-CoA oxidase
long-chain fatty-acyl-CoA biosynthetic process
alpha-linolenic acid metabolic process
dicarboxylic acid catabolic process
negative regulation of CD4 biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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