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This antibody is predicted to react with canine, mouse and porcine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: actin-related protein 1 alpha; actin-related protein 1 homolog A; Actin-RPV; actr1a {ECO:0000250|UniProtKB:P61163}; Alpha-centractin; ARP1; ARP1 actin related protein 1 homolog A; ARP1 actin-related protein 1 homolog A, centractin alpha; Arp1 centractin alpha; Arp1 contractin alpha; Centractin; Centrosome-associated actin homolog; FLJ52695; FLJ52800; FLJ55002; yeast homolog A
Gene Aliases: ACTR1A; alpha-Arp1; ARP1; Arp1A; CTRN1
UniProt ID: (Human) P61163, (Dog) P61162, (Mouse) P61164, (Rat) P85515
Entrez Gene ID: (Human) 10121, (Dog) 403791, (Mouse) 54130, (Rat) 294010
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