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Product Details
PA5-30356
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 1 and 206 of Human ACTR1A
Conjugate
Form
Liquid
Concentration
0.65 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2547830
Product Specific Information
Recommended positive controls: 293T, mouse liver.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (97%), Dog (100%), Chicken (98%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-related protein 1 alpha; actin-related protein 1 homolog A; Actin-RPV; Alpha-centractin; ARP1; ARP1 actin-related protein 1 homolog A, centractin alpha; Arp1 centractin alpha; Arp1 contractin alpha; Centractin; Centrosome-associated actin homolog; FLJ52695; FLJ52800; FLJ55002; yeast homolog A
Gene Aliases: ACTR1A; alpha-Arp1; ARP1; Arp1A; CTRN1
UniProt ID: (Human) P61163, (Mouse) P61164
Entrez Gene ID: (Human) 10121, (Mouse) 54130
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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