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ACTR1B Antibody (PA5-116639) in IHC (P)
Immunohistochemistry analysis of ACTR1B in paraffin-embedded human colon carcinoma. Samples were incubated with ACTR1B Polyclonal antibody (Product # PA5-116639) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-116639
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human ACTR1B (NP_0057261)
Conjugate
Form
Liquid
Concentration
1.86 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901270
Product Specific Information
Positive Samples: Mouse thymus, Mouse brain, Mouse heart, Rat lung
Immunogen sequence: MESYDIIANQ PVVIDNGSGV IKAGFAGDQI PKYCFPNYVG RPKHMRVMAG ALEGDLFIGP KAEEHRGLLT IRYPMEHGVV RDWNDMERIW QYVYSKDQLQ TFSEE
Target Information
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Actin-related protein 1B; ARP1 actin-related protein 1 homolog B, centractin beta; ARP1B; Beta-centractin; centractin beta; yeast homolog B
Gene Aliases: 2310066K23Rik; AA960180; ACTR1B; AI851923; ARP1B; CTRN2; PC3
UniProt ID: (Human) P42025, (Mouse) Q8R5C5
Entrez Gene ID: (Human) 10120, (Rat) 316333, (Mouse) 226977
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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