Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Recommended positive controls: IMR32, mouse brain.
Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-related protein 1B; ARP1 actin-related protein 1 homolog B, centractin beta; ARP1B; Beta-centractin; centractin beta; yeast homolog B
Gene Aliases: 2310066K23Rik; AA960180; ACTR1B; AI851923; ARP1B; CTRN2; PC3
UniProt ID: (Human) P42025, (Mouse) Q8R5C5
Entrez Gene ID: (Human) 10120, (Mouse) 226977
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