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ACTR1B Antibody (MA5-52596) in ICC/IF
Immunocytochemistry analysis of ACTR1B in HT-1080 cells. Nuclei were stained blue with DAPI; ACTR1B recombinant monoclonal antibody (Product # MA5-52596) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Product Details
MA5-52596
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB3135
Immunogen
A synthetic peptide of human ACTR1B (301-376AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Actin-related protein 1B; ARP1 actin-related protein 1 homolog B, centractin beta; ARP1B; Beta-centractin; centractin beta; yeast homolog B
Gene Aliases: 2310066K23Rik; AA960180; ACTR1B; AI851923; ARP1B; CTRN2; PC3
UniProt ID: (Human) P42025, (Mouse) Q8R5C5
Entrez Gene ID: (Human) 10120, (Rat) 316333, (Mouse) 226977
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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