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Product Details
13328-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ADA Fusion Protein Ag4128 (1-363 aa encoded by BC040226)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAQTPAFDK PKVELHVHLD GSIKPETILY YGRRRGIALP ANTAEGLLNV IGMDKPLTLP DFLAKFDYYM PAIAGCREAI KRIAYEFVEM KAKEGVVYVE VRYSPHLLAN SKVEPIPWNQ AEGDLTPDEV VALVGQGLQE GERDFGVKAR SILCCMRHQP NWSPKVVELC KKYQQQTVVA IDLAGDETIP GSSLLPGHVQ AYQEAVKSGI HRTVHAGEVG SAEVVKEAVD ILKTERLGHG YHTLEDQALY NRLRQENMHF EICPWSSYLT GAWKPDTEHA VIRLKNDQAN YSLNTDDPLI FKSTLDTDYQ MTKRDMGFTE EEFKRLNINA AKSSFLPEDE KRELLDLLYK AYGMPPSASA GQNL (1-363 aa encoded by BC040226)
Target Information
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adenosine aminohydrolase; Adenosine deaminase; RP11-61L14.5
Gene Aliases: ADA; ADA1
UniProt ID: (Human) P00813, (Mouse) P03958
Entrez Gene ID: (Human) 100, (Mouse) 11486
response to hypoxia
histamine secretion
trophectodermal cell differentiation
liver development
placenta development
germinal center B cell differentiation
positive regulation of germinal center formation
negative regulation of leukocyte migration
negative regulation of mature B cell apoptotic process
adenosine catabolic process
deoxyadenosine catabolic process
aging
purine ribonucleoside monophosphate biosynthetic process
positive regulation of heart rate
positive regulation of B cell proliferation
purine nucleotide salvage
positive regulation of T cell differentiation in thymus
response to vitamin E
regulation of cell-cell adhesion mediated by integrin
T cell activation
negative regulation of circadian sleep/wake cycle, non-REM sleep
response to drug
response to hydrogen peroxide
purine-containing compound salvage
hypoxanthine salvage
response to morphine
positive regulation of smooth muscle contraction
dATP catabolic process
inosine biosynthetic process
xanthine biosynthetic process
positive regulation of alpha-beta T cell differentiation
lung alveolus development
Peyer's patch development
embryonic digestive tract development
negative regulation of inflammatory response
positive regulation of calcium-mediated signaling
positive regulation of T cell receptor signaling pathway
negative regulation of adenosine receptor signaling pathway
negative regulation of penile erection
negative regulation of thymocyte apoptotic process
negative regulation of mucus secretion
in utero embryonic development
cell adhesion
nucleotide metabolic process
lung development
negative regulation of apoptotic process
regulation of T cell differentiation
positive regulation of T cell differentiation
adenosine metabolic process
hypoxanthine biosynthetic process
positive regulation of T cell activation
Performance Guarantee
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