Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 6
ADA Antibody (H00000100-D01P) in WB
Western Blot analysis of ADA expression in transfected 293T cell line (H00000100-T01) by ADA MaxPab polyclonal antibody.
Lane 1: ADA transfected lysate(40.80 KDa).
Lane 2: Non-transfected lysate.
Lane 1: ADA transfected lysate(40.80 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00000100-D01P
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ADA (NP_000013.2, 1 a.a. approximately 363 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MAQTPAFDKP KVELHVHLDG SIKPETILYY GRRRGIALPA NTAEGLLNVI GMDKPLTLPD FLAKFDYYMP AIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVEPIPWNQA EGDLTPDEVV ALVGQGLQEG ERDFGVKARS ILCCMRHQPN WSPKVVELCK KYQQQTVVAI DLAGDETIPG SSLLPGHVQA YQEAVKSGIH RTVHAGEVGS AEVVKEAVDI LKTERLGHGY HTLEDQALYN RLRQENMHFE ICPWSSYLTG AWKPDTEHAV IRLKNDQANY SLNTDDPLIF KSTLDTDYQM TKRDMGFTEE EFKRLNINAA KSSFLPEDEK RELLDLLYKA YGMPPSASAG QNL
Target Information
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Adenosine aminohydrolase; Adenosine deaminase; RP11-61L14.5
Gene Aliases: ADA; ADA1
UniProt ID: (Human) P00813, (Mouse) P03958, (Rat) Q920P6
Entrez Gene ID: (Human) 100, (Mouse) 11486, (Rat) 24165
response to hypoxia
histamine secretion
trophectodermal cell differentiation
liver development
placenta development
germinal center B cell differentiation
positive regulation of germinal center formation
negative regulation of leukocyte migration
negative regulation of mature B cell apoptotic process
adenosine catabolic process
deoxyadenosine catabolic process
aging
purine ribonucleoside monophosphate biosynthetic process
positive regulation of heart rate
positive regulation of B cell proliferation
purine nucleotide salvage
positive regulation of T cell differentiation in thymus
response to vitamin E
regulation of cell-cell adhesion mediated by integrin
T cell activation
negative regulation of circadian sleep/wake cycle, non-REM sleep
response to drug
response to hydrogen peroxide
purine-containing compound salvage
hypoxanthine salvage
response to morphine
positive regulation of smooth muscle contraction
dATP catabolic process
inosine biosynthetic process
xanthine biosynthetic process
positive regulation of alpha-beta T cell differentiation
lung alveolus development
Peyer's patch development
embryonic digestive tract development
negative regulation of inflammatory response
positive regulation of calcium-mediated signaling
positive regulation of T cell receptor signaling pathway
negative regulation of adenosine receptor signaling pathway
negative regulation of penile erection
negative regulation of thymocyte apoptotic process
negative regulation of mucus secretion
in utero embryonic development
cell adhesion
nucleotide metabolic process
lung development
negative regulation of apoptotic process
regulation of T cell differentiation
positive regulation of T cell differentiation
adenosine metabolic process
hypoxanthine biosynthetic process
positive regulation of T cell activation
regulation of circadian sleep/wake cycle, sleep
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support