Product References
ADAM12 promotes gemcitabine resistance by activating EGFR signaling pathway and induces EMT in bladder cancer.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Wang R,Gao D,Chen C,Fan G,Cheng H,Tao Y,Lu J,Tian J,Wang Y,Wang Z
Mon May 01 00:00:00 EDT 2023
ADAM12 promotes gemcitabine resistance by activating EGFR signaling pathway and induces EMT in bladder cancer.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Wang R,Gao D,Chen C,Fan G,Cheng H,Tao Y,Lu J,Tian J,Wang Y,Wang Z
Mon May 01 00:00:00 EDT 2023
ADAM12 promotes clear cell renal cell carcinoma progression and triggers EMT via EGFR/ERK signaling pathway.
Journal of translational medicine
Xu J,Wang Y,Jiang J,Yin C,Shi B
Mon Jan 30 00:00:00 EST 2023
ADAM12 promotes clear cell renal cell carcinoma progression and triggers EMT via EGFR/ERK signaling pathway.
Journal of translational medicine
Xu J,Wang Y,Jiang J,Yin C,Shi B
Mon Jan 30 00:00:00 EST 2023
Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations.
Cell reports
Leinroth AP,Mirando AJ,Rouse D,Kobayahsi Y,Tata PR,Rueckert HE,Liao Y,Long JT,Chakkalakal JV,Hilton MJ
Tue May 10 00:00:00 EDT 2022
Vaccination-based immunotherapy to target profibrotic cells in liver and lung.
Cell stem cell
Sobecki M,Chen J,Krzywinska E,Nagarajan S,Fan Z,Nelius E,Monné Rodriguez JM,Seehusen F,Hussein A,Moschini G,Hajam EY,Kiran R,Gotthardt D,Debbache J,Badoual C,Sato T,Isagawa T,Takeda N,Tanchot C,Tartour E,Weber A,Werner S,Loffing J,Sommer L,Sexl V,Münz C,Feghali-Bostwick C,Pachera E,Distler O,Snedeker J,Jamora C,Stockmann C
Thu Oct 06 00:00:00 EDT 2022
Dysregulation of interaction between LOXhigh fibroblast and smooth muscle cells contributes to the pathogenesis of aortic dissection.
Theranostics
Chen Y,Zhang T,Yao F,Gao X,Li D,Fu S,Mao L,Liu F,Zhang X,Xu Y,Deng J,Li W,Fan G,Xiao C,Chen Y,Wang L,Guo W,Zhou B
Thu Mar 10 00:00:00 EST 2022
MicroRNA-149 Regulates Proliferation, Migration, and Invasion of Pituitary Adenoma Cells by Targeting ADAM12 and MMP14.
Current medical science
Zhang Z,Schäfer A,Voellger B,Wang JW,Lei T,Nimsky C,Bartsch JW
Thu Dec 01 00:00:00 EST 2022
Targeting cardiomyocyte ADAM10 ectodomain shedding promotes survival early after myocardial infarction.
Nature communications
Klapproth E,Witt A,Klose P,Wiedemann J,Vavilthota N,Künzel SR,Kämmerer S,Günscht M,Sprott D,Lesche M,Rost F,Dahl A,Rauch E,Kattner L,Weber S,Mirtschink P,Kopaliani I,Guan K,Lorenz K,Saftig P,Wagner M,El-Armouche A
Sat Dec 10 00:00:00 EST 2022
Impact of disintegrin and metalloproteinase domain-containing protein 12 on pancreatic ductal adenocarcinoma treated with surgical resection and perioperative chemotherapy.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Sakoda T,Uemura K,Kondo N,Sumiyoshi T,Okada K,Seo S,Otsuka H,Murakami Y,Takahashi S
Sun May 01 00:00:00 EDT 2022
Methylation status of ADAM12 promoter are associated with its expression levels in colorectal cancer.
Pathology, research and practice
Wang Y,Zhang J,Cao H,Han F,Zhang H,Xu E
Sat May 01 00:00:00 EDT 2021
Multi-organ metastasis as destination for breast cancer cells guided by biomechanical architecture.
American journal of cancer research
Lin Q,Chen X,Meng F,Ogawa K,Li M,Song R,Zhang S,Zhang Z,Kong X,Xu Q,He F,Liu D,Bai X,Sun B,Hung MC,Liu L,Wands JR,Dong X
Tue Jul 13 00:00:00 EDT 2021
Molecular characteristics of established trophoblast-derived cell lines.
Placenta
Pastuschek J,Nonn O,Gutiérrez-Samudio RN,Murrieta-Coxca JM,Müller J,Sanft J,Huppertz B,Markert UR,Groten T,Morales-Prieto DM
Sat May 01 00:00:00 EDT 2021
Selective estrogen receptor modulators decrease invasiveness in pituitary adenoma cell lines AtT-20 and TtT/GF by affecting expression of MMP-14 and ADAM12.
FEBS open bio
Zhang Z,Bartsch JW,Benzel J,Lei T,Nimsky C,Voellger B
Sun Nov 01 00:00:00 EDT 2020
ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells.
International journal of oncology
Wang L,Tan Z,Zhang Y,Kady Keita N,Liu H,Zhang Y
Fri May 01 00:00:00 EDT 2020
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
International journal of molecular medicine
Li W,Wang D,Sun X,Zhang Y,Wang L,Suo J
Fri Feb 01 00:00:00 EST 2019
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
International journal of molecular medicine
Li W,Wang D,Sun X,Zhang Y,Wang L,Suo J
Fri Feb 01 00:00:00 EST 2019
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
International journal of molecular medicine
Li W,Wang D,Sun X,Zhang Y,Wang L,Suo J
Fri Feb 01 00:00:00 EST 2019
ADAM17 promotes lymph node metastasis in gastric cancer via activation of the Notch and Wnt signaling pathways.
International journal of molecular medicine
Li W,Wang D,Sun X,Zhang Y,Wang L,Suo J
Fri Feb 01 00:00:00 EST 2019
Involvement of ADAM12 in Chondrocyte Differentiation by Regulation of TGF-β1-Induced IGF-1 and RUNX-2 Expressions.
Calcified tissue international
Horita M,Nishida K,Hasei J,Furumatsu T,Sakurai M,Onodera Y,Fukuda K,Salter DM,Ozaki T
Mon Jul 01 00:00:00 EDT 2019
Genetic screens reveal mechanisms for the transcriptional regulation of tissue-specific genes in normal cells and tumors.
Nucleic acids research
Naciri I,Laisné M,Ferry L,Bourmaud M,Gupta N,Di Carlo S,Huna A,Martin N,Peduto L,Bernard D,Kirsh O,Defossez PA
Tue Apr 23 00:00:00 EDT 2019
Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway.
Journal of hematology & oncology
Ogawa K,Lin Q,Li L,Bai X,Chen X,Chen H,Kong R,Wang Y,Zhu H,He F,Xu Q,Liu L,Li M,Zhang S,Nagaoka K,Carlson R,Safran H,Charpentier K,Sun B,Wands J,Dong X
Mon Dec 30 00:00:00 EST 2019
SILAC Quantitative Proteomics and Biochemical Analyses Reveal a Novel Molecular Mechanism by Which ADAM12S Promotes the Proliferation, Migration, and Invasion of Small Cell Lung Cancer Cells through Upregulating Hexokinase 1.
Journal of proteome research
Duan Q,Li D,Xiong L,Chang Z,Xu G
Fri Jul 05 00:00:00 EDT 2019
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang J,Zhang Z,Li R,Mao F,Sun W,Chen J,Zhang H,Bartsch JW,Shu K,Lei T
Mon Jan 01 00:00:00 EST 2018
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang J,Zhang Z,Li R,Mao F,Sun W,Chen J,Zhang H,Bartsch JW,Shu K,Lei T
Mon Jan 01 00:00:00 EST 2018
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang J,Zhang Z,Li R,Mao F,Sun W,Chen J,Zhang H,Bartsch JW,Shu K,Lei T
Mon Jan 01 00:00:00 EST 2018
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang J,Zhang Z,Li R,Mao F,Sun W,Chen J,Zhang H,Bartsch JW,Shu K,Lei T
Mon Jan 01 00:00:00 EST 2018
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Wang J,Zhang Z,Li R,Mao F,Sun W,Chen J,Zhang H,Bartsch JW,Shu K,Lei T
Mon Jan 01 00:00:00 EST 2018
Quantitative proteomics and biochemical analyses reveal the role of endoplasmin in the regulation of the expression and secretion of A Disintegrin And Metalloproteinase 12.
Journal of proteomics
Xiong L,Yan W,Zubia E,Zhou Y,Zhang Y,Duan Q,Narayan M,Xu G
Sat Jun 30 00:00:00 EDT 2018
The transcriptional profiles and functional implications of long non-coding RNAs in the unfolded protein response.
Scientific reports
Quan H,Fan Q,Li C,Wang YY,Wang L
Wed Mar 21 00:00:00 EDT 2018
The transcriptional profiles and functional implications of long non-coding RNAs in the unfolded protein response.
Scientific reports
Quan H,Fan Q,Li C,Wang YY,Wang L
Wed Mar 21 00:00:00 EDT 2018
ADAM12 Is a Novel Regulator of Tumor Angiogenesis via STAT3 Signaling.
Molecular cancer research : MCR
Roy R,Dagher A,Butterfield C,Moses MA
Wed Nov 01 00:00:00 EDT 2017
ADAM12 Is a Novel Regulator of Tumor Angiogenesis via STAT3 Signaling.
Molecular cancer research : MCR
Roy R,Dagher A,Butterfield C,Moses MA
Wed Nov 01 00:00:00 EDT 2017
Soluble Delta-like ligand 1 alters human endometrial epithelial cell adhesive capacity.
Reproduction, fertility, and development
Van Sinderen M,Oyanedel J,Menkhorst E,Cuman C,Rainczuk K,Winship A,Salamonsen L,Edgell T,Dimitriadis E
Sat Apr 01 00:00:00 EDT 2017
Soluble Delta-like ligand 1 alters human endometrial epithelial cell adhesive capacity.
Reproduction, fertility, and development
Van Sinderen M,Oyanedel J,Menkhorst E,Cuman C,Rainczuk K,Winship A,Salamonsen L,Edgell T,Dimitriadis E
Sat Apr 01 00:00:00 EDT 2017
Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization.
Scientific reports
Wang D,Wang A,Wu F,Qiu X,Li Y,Chu J,Huang WC,Xu K,Gong X,Li S
Tue Jan 10 00:00:00 EST 2017
Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization.
Scientific reports
Wang D,Wang A,Wu F,Qiu X,Li Y,Chu J,Huang WC,Xu K,Gong X,Li S
Tue Jan 10 00:00:00 EST 2017
Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.
International journal of cancer
Wang J,Voellger B,Benzel J,Schlomann U,Nimsky C,Bartsch JW,Carl B
Thu Sep 15 00:00:00 EDT 2016
Metalloproteinases ADAM12 and MMP-14 are associated with cavernous sinus invasion in pituitary adenomas.
International journal of cancer
Wang J,Voellger B,Benzel J,Schlomann U,Nimsky C,Bartsch JW,Carl B
Thu Sep 15 00:00:00 EDT 2016
Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.
Journal of proteomics
Zhou Y,Xiong L,Zhang Y,Yu R,Jiang X,Xu G
Tue Oct 04 00:00:00 EDT 2016
Quantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells.
Journal of proteomics
Zhou Y,Xiong L,Zhang Y,Yu R,Jiang X,Xu G
Tue Oct 04 00:00:00 EDT 2016
ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion.
Cell death and differentiation
Aghababaei M,Hogg K,Perdu S,Robinson WP,Beristain AG
Tue Dec 01 00:00:00 EST 2015
ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion.
Cell death and differentiation
Aghababaei M,Hogg K,Perdu S,Robinson WP,Beristain AG
Tue Dec 01 00:00:00 EST 2015
Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression.
Molecular carcinogenesis
Rao VH,Vogel K,Yanagida JK,Marwaha N,Kandel A,Trempus C,Repertinger SK,Hansen LA
Thu Oct 01 00:00:00 EDT 2015
Erbb2 up-regulation of ADAM12 expression accelerates skin cancer progression.
Molecular carcinogenesis
Rao VH,Vogel K,Yanagida JK,Marwaha N,Kandel A,Trempus C,Repertinger SK,Hansen LA
Thu Oct 01 00:00:00 EDT 2015
Urinary ADAM12 and MMP-9/NGAL complex detect the presence of gastric cancer.
Cancer prevention research (Philadelphia, Pa.)
Shimura T,Dagher A,Sachdev M,Ebi M,Yamada T,Yamada T,Joh T,Moses MA
Sun Mar 01 00:00:00 EST 2015
Urinary ADAM12 and MMP-9/NGAL complex detect the presence of gastric cancer.
Cancer prevention research (Philadelphia, Pa.)
Shimura T,Dagher A,Sachdev M,Ebi M,Yamada T,Yamada T,Joh T,Moses MA
Sun Mar 01 00:00:00 EST 2015
Notch-dependent RBPJκ inhibits proliferation of human cytotrophoblasts and their differentiation into extravillous trophoblasts.
Molecular human reproduction
Velicky P,Haider S,Otti GR,Fiala C,Pollheimer J,Knöfler M
Fri Aug 01 00:00:00 EDT 2014
Notch-dependent RBPJκ inhibits proliferation of human cytotrophoblasts and their differentiation into extravillous trophoblasts.
Molecular human reproduction
Velicky P,Haider S,Otti GR,Fiala C,Pollheimer J,Knöfler M
Fri Aug 01 00:00:00 EDT 2014
A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development.
Molecular human reproduction
Aghababaei M,Perdu S,Irvine K,Beristain AG
Sat Mar 01 00:00:00 EST 2014
A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development.
Molecular human reproduction
Aghababaei M,Perdu S,Irvine K,Beristain AG
Sat Mar 01 00:00:00 EST 2014
A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development.
Molecular human reproduction
Aghababaei M,Perdu S,Irvine K,Beristain AG
Sat Mar 01 00:00:00 EST 2014
A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development.
Molecular human reproduction
Aghababaei M,Perdu S,Irvine K,Beristain AG
Sat Mar 01 00:00:00 EST 2014
A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development.
Molecular human reproduction
Aghababaei M,Perdu S,Irvine K,Beristain AG
Sat Mar 01 00:00:00 EST 2014
Extravillous trophoblast-associated ADAM12 exerts pro-invasive properties, including induction of integrin beta 1-mediated cellular spreading.
Biology of reproduction
Biadasiewicz K,Fock V,Dekan S,Proestling K,Velicky P,Haider S,Knöfler M,Fröhlich C,Pollheimer J
Thu May 01 00:00:00 EDT 2014
Extravillous trophoblast-associated ADAM12 exerts pro-invasive properties, including induction of integrin beta 1-mediated cellular spreading.
Biology of reproduction
Biadasiewicz K,Fock V,Dekan S,Proestling K,Velicky P,Haider S,Knöfler M,Fröhlich C,Pollheimer J
Thu May 01 00:00:00 EDT 2014
A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis.
European journal of cancer (Oxford, England : 1990)
Georges S,Chesneau J,Hervouet S,Taurelle J,Gouin F,Redini F,Padrines M,Heymann D,Fortun Y,Verrecchia F
Sat Jun 01 00:00:00 EDT 2013
A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis.
European journal of cancer (Oxford, England : 1990)
Georges S,Chesneau J,Hervouet S,Taurelle J,Gouin F,Redini F,Padrines M,Heymann D,Fortun Y,Verrecchia F
Sat Jun 01 00:00:00 EDT 2013
Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia.
The Journal of cell biology
Díaz B,Yuen A,Iizuka S,Higashiyama S,Courtneidge SA
Mon Apr 15 00:00:00 EDT 2013
Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia.
The Journal of cell biology
Díaz B,Yuen A,Iizuka S,Higashiyama S,Courtneidge SA
Mon Apr 15 00:00:00 EDT 2013
ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins.
The Biochemical journal
Fröhlich C,Klitgaard M,Noer JB,Kotzsch A,Nehammer C,Kronqvist P,Berthelsen J,Blobel C,Kveiborg M,Albrechtsen R,Wewer UM
Wed May 15 00:00:00 EDT 2013
ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins.
The Biochemical journal
Fröhlich C,Klitgaard M,Noer JB,Kotzsch A,Nehammer C,Kronqvist P,Berthelsen J,Blobel C,Kveiborg M,Albrechtsen R,Wewer UM
Wed May 15 00:00:00 EDT 2013
A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion.
Oncogene
Rao VH,Kandel A,Lynch D,Pena Z,Marwaha N,Deng C,Watson P,Hansen LA
Thu Jun 07 00:00:00 EDT 2012
A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion.
Oncogene
Rao VH,Kandel A,Lynch D,Pena Z,Marwaha N,Deng C,Watson P,Hansen LA
Thu Jun 07 00:00:00 EDT 2012
A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion.
Oncogene
Rao VH,Kandel A,Lynch D,Pena Z,Marwaha N,Deng C,Watson P,Hansen LA
Thu Jun 07 00:00:00 EDT 2012
A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion.
Oncogene
Rao VH,Kandel A,Lynch D,Pena Z,Marwaha N,Deng C,Watson P,Hansen LA
Thu Jun 07 00:00:00 EDT 2012
Functional analysis of a breast cancer-associated mutation in the intracellular domain of the metalloprotease ADAM12.
PloS one
Stautz D,Wewer UM,Kveiborg M
Thu Dec 13 00:00:00 EST 2012
Functional analysis of a breast cancer-associated mutation in the intracellular domain of the metalloprotease ADAM12.
PloS one
Stautz D,Wewer UM,Kveiborg M
Thu Dec 13 00:00:00 EST 2012
Functional analysis of a breast cancer-associated mutation in the intracellular domain of the metalloprotease ADAM12.
PloS one
Stautz D,Wewer UM,Kveiborg M
Thu Dec 13 00:00:00 EST 2012
Functional analysis of a breast cancer-associated mutation in the intracellular domain of the metalloprotease ADAM12.
PloS one
Stautz D,Wewer UM,Kveiborg M
Thu Dec 13 00:00:00 EST 2012
ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression.
Molecular cancer research : MCR
Fröhlich C,Nehammer C,Albrechtsen R,Kronqvist P,Kveiborg M,Sehara-Fujisawa A,Mercurio AM,Wewer UM
Tue Nov 01 00:00:00 EDT 2011
ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression.
Molecular cancer research : MCR
Fröhlich C,Nehammer C,Albrechtsen R,Kronqvist P,Kveiborg M,Sehara-Fujisawa A,Mercurio AM,Wewer UM
Tue Nov 01 00:00:00 EDT 2011
ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression.
Molecular cancer research : MCR
Fröhlich C,Nehammer C,Albrechtsen R,Kronqvist P,Kveiborg M,Sehara-Fujisawa A,Mercurio AM,Wewer UM
Tue Nov 01 00:00:00 EDT 2011
ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression.
Molecular cancer research : MCR
Fröhlich C,Nehammer C,Albrechtsen R,Kronqvist P,Kveiborg M,Sehara-Fujisawa A,Mercurio AM,Wewer UM
Tue Nov 01 00:00:00 EDT 2011
ADAM12 transmembrane and secreted isoforms promote breast tumor growth: a distinct role for ADAM12-S protein in tumor metastasis.
The Journal of biological chemistry
Roy R,Rodig S,Bielenberg D,Zurakowski D,Moses MA
Fri Jun 10 00:00:00 EDT 2011
ADAM12 transmembrane and secreted isoforms promote breast tumor growth: a distinct role for ADAM12-S protein in tumor metastasis.
The Journal of biological chemistry
Roy R,Rodig S,Bielenberg D,Zurakowski D,Moses MA
Fri Jun 10 00:00:00 EDT 2011
ADAM12 transmembrane and secreted isoforms promote breast tumor growth: a distinct role for ADAM12-S protein in tumor metastasis.
The Journal of biological chemistry
Roy R,Rodig S,Bielenberg D,Zurakowski D,Moses MA
Fri Jun 10 00:00:00 EDT 2011
ADAM12 transmembrane and secreted isoforms promote breast tumor growth: a distinct role for ADAM12-S protein in tumor metastasis.
The Journal of biological chemistry
Roy R,Rodig S,Bielenberg D,Zurakowski D,Moses MA
Fri Jun 10 00:00:00 EDT 2011