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ADAM12 is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. Two forms of ADAM12 have been described: ADAM12S and ADAM12L (short and long forms). The short form is a soluble form lacking the transmembrane and cytoplasmic domains. The short form of ADAM12 was reported to provoke myogenesis, and the lack of cytoplasmic domain suggests different regulation pathways (although both forms can be expressed in the same tissue).
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Protein Aliases: a disintegrin and metallopeptidase domain 12 (meltrin alpha); a disintegrin and metalloprotease domain 12; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 12 (meltrin alpha); ADAM; ADAM 12; ADAM metallopeptidase domain 12; ADAMs; Disintegrin and metalloproteinase domain-containing protein 12; meltrin alpha; Meltrin-alpha; metalloendopeptidases; metalloprotease-disintegrin 12 transmembrane; PRO545; RP11-295J3.5; UNQ346
Gene Aliases: ADAM12; ADAM12-OT1; CAR10; MCMP; MCMPMltna; mKIAA4001; MLTN; MLTNA; UNQ346/PRO545
UniProt ID: (Human) O43184, (Mouse) Q61824
Entrez Gene ID: (Human) 8038, (Mouse) 11489, (Rat) 679837
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