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Product Details
PA5-121158
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 589-738 of human ADAM12 (NP_067673.2).
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914730
Product Specific Information
Positive test controls include: Mouse brain, Mouse thymus, Mouse fat, Mouse ovary, Rat brain. The target is usually found in the following locations: Cell membrane, Secreted, Single-pass type I membrane protein.
Immunogen sequence: ASRPVIGTNA VSIETNIPLQ QGGRILCRGT HVYLGDDMPD PGLVLAGTKC ADGKICLNRQ CQNISVFGVH ECAMQCHGRG VCNNRKNCHC EAHWAPPFCD KFGFGGSTDS GPIRQAEARQ EAAESNRERG QGQEPVGSQE HASTASLTLI
Target Information
ADAM12 is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. Two forms of ADAM12 have been described: ADAM12S and ADAM12L (short and long forms). The short form is a soluble form lacking the transmembrane and cytoplasmic domains. The short form of ADAM12 was reported to provoke myogenesis, and the lack of cytoplasmic domain suggests different regulation pathways (although both forms can be expressed in the same tissue).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metallopeptidase domain 12 (meltrin alpha); a disintegrin and metalloprotease domain 12; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 12 (meltrin alpha); ADAM; ADAM 12; ADAM metallopeptidase domain 12; ADAMs; Disintegrin and metalloproteinase domain-containing protein 12; meltrin alpha; Meltrin-alpha; metalloendopeptidases; metalloprotease-disintegrin 12 transmembrane; PRO545; RP11-295J3.5; UNQ346
Gene Aliases: ADAM12; ADAM12-OT1; CAR10; MCMP; MCMPMltna; mKIAA4001; MLTN; MLTNA; UNQ346/PRO545
UniProt ID: (Human) O43184, (Mouse) Q61824
Entrez Gene ID: (Human) 8038, (Mouse) 11489, (Rat) 679837
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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