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FIGURE: 1 / 1
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform.
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Protein Aliases: a disintegrin and metallopeptidase domain 28; a disintegrin and metalloprotease domain 28; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 28; ADAM; ADAM 28; ADAMs; disintegrin 1; Disintegrin and metalloproteinase domain-containing protein 28; eMDC II; Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; epididymial metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; MDC-L; metalloendopeptidases; metalloproteinase-disintegrin domain containing protein TECADAM; Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L; metalloproteinase-like, disintegrin-like, and cysteine-rich protein-L; TECADAM; Thymic epithelial cell-ADAM
Gene Aliases: ADAM 28; ADAM23; ADAM28; C130072N01Rik; D430033C21Rik; Dtgn1; eMDC II; eMDCII; MDC-L; MDC-Lm; MDC-Ls; MDCL; TECADAM
UniProt ID: (Human) Q9UKQ2, (Mouse) Q9JLN6
Entrez Gene ID: (Human) 10863, (Mouse) 13522, (Rat) 290344
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