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FIGURE: 1 / 3
ADAM33 Antibody (PA5-103573) in ICC/IF
Immunocytochemistry analysis of ADAM33 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with ADAM33 polyclonal antibody (Product # PA5-103573) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-103573
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ADAM33(Accession Q9BZ11), corresponding to amino acid residues L301-L351.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2852909
Product Specific Information
Antibody detects endogenous levels of total ADAM33.
Target Information
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloprotease 33; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 33; ADAM; ADAM 33; ADAMs; Disintegrin and metalloproteinase domain-containing protein 33; disintegrin and reprolysin metalloproteinase family protein; DKFZp434K0521; FLJ35308; FLJ36751; HGNC:15478; metalloendopeptidases; MGC149823; MGC71889; RP23-228H14.4; RP5-964F7.2
Gene Aliases: ADAM33; C20orf153; DJ964F7.1; UNQ873/PRO1891
UniProt ID: (Human) Q9BZ11
Entrez Gene ID: (Human) 80332
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