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In direct ELISAs, less than 1% cross-reactivity with recombinant mouse (rm) ADAM8, rmADAM10, and rmADAM15 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a disintegrin and metalloprotease domain 33; a disintegrin and metalloproteinase; ADAM; ADAM 33; ADAMs; Disintegrin and metalloproteinase domain-containing protein 33; DKFZp434K0521; FLJ35308; FLJ36751; HGNC:15478; metalloendopeptidases; MGC149823; MGC71889; RP23-228H14.4; RP5-964F7.2
Gene Aliases: Adam33; Adaml
UniProt ID: (Mouse) Q923W9
Entrez Gene ID: (Mouse) 110751
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