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Immunogen sequence: NSAGDAHGNC GQDSEGHFLP CAGRDALCGK LQCQGGKPSL LAPHMVPVDS TVHLDGQEVT CRGALALPSA QLD
Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 64%.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a disintegrin and metalloprotease 33; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 33; ADAM; ADAM 33; ADAMs; Disintegrin and metalloproteinase domain-containing protein 33; disintegrin and reprolysin metalloproteinase family protein; DKFZp434K0521; FLJ35308; FLJ36751; HGNC:15478; metalloendopeptidases; MGC149823; MGC71889; RP23-228H14.4; RP5-964F7.2
Gene Aliases: ADAM33; C20orf153; DJ964F7.1; UNQ873/PRO1891
UniProt ID: (Human) Q9BZ11
Entrez Gene ID: (Human) 80332
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