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In Western blots, no cross-reactivity with recombinant mouse ADAM9, 10, 15, recombinant human (rh) ADAM8, rhTACE/ADAM17, rhADAM19, or rhADAM33 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein is a type I transmembrane protein implicated in asthma and bronchial hyperresponsiveness. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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Protein Aliases: a disintegrin and metalloprotease domain 33; a disintegrin and metalloproteinase; ADAM; ADAM 33; ADAMs; Disintegrin and metalloproteinase domain-containing protein 33; DKFZp434K0521; FLJ35308; FLJ36751; HGNC:15478; metalloendopeptidases; MGC149823; MGC71889; RP23-228H14.4; RP5-964F7.2
Gene Aliases: Adam33; Adaml
UniProt ID: (Mouse) Q923W9
Entrez Gene ID: (Mouse) 110751
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