Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 2
ADAM9 Antibody (PA5-47968) in WB
Western blot analysis of ADAM9 in WI‚38 human lung fibroblast cell line and U‚87 MG human glioblastoma/astrocytoma cell line. Samples were incubated in ADAM9 polyclonal antibody (Product # PA5-47968) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Goat IgG secondary antibody. Specific bands were detected for ADAM9 at approximately 110 and 80 kDa (as indicated). This experiment was conducted under reducing conditions.
Product Details
PA5-47968
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human ADAM9 Ala206-Asp697
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2607933
Product Specific Information
In sandwich ELISAs, approximately 20% cross-reactivity with recombinant mouse (rm) rmADAM9 is observed and less than 0.05% cross-reactivity with recombinant human (rh) rhADAM8, rhADAM10, rhTACE, rhTIMP-1, rhTIMP-2, rhTIMP-3, rhTIMP-4, rhBACE-1 and rmADAM10 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; ADAM; ADAM 9; ADAM metallopeptidase domain 9 (meltrin gamma); ADAMs; Cellular disintegrin-related protein; cone rod dystrophy 9; Disintegrin and metalloproteinase domain-containing protein 9; MDC 9; Meltrin-gamma; metalloendopeptidases; Metalloprotease/disintegrin/cysteine-rich protein 9; Myeloma cell metalloproteinase; OTTHUMP00000216481; OTTHUMP00000216484; OTTHUMP00000216485
Gene Aliases: ADAM9; CORD9; KIAA0021; MCMP; MDC9; MLTNG
UniProt ID: (Human) Q13443
Entrez Gene ID: (Human) 8754
activation of MAPKK activity
membrane protein ectodomain proteolysis
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
response to manganese ion
cell migration
keratinocyte differentiation
cell adhesion mediated by integrin
positive regulation of cell adhesion mediated by integrin
cell-cell adhesion mediated by integrin
positive regulation of macrophage fusion
response to tumor necrosis factor
monocyte activation
response to hydrogen peroxide
positive regulation of protein secretion
positive regulation of membrane protein ectodomain proteolysis
PMA-inducible membrane protein ectodomain proteolysis
response to glucocorticoid
positive regulation of keratinocyte migration
response to calcium ion
cellular response to lipopolysaccharide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support