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ADAMTS1 Antibody (MA5-55378) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of NIH/3T3 cells using ADAMTS1 Recombinant Monoclonal Antibody (Product # MA5-55378) at a dilution of 1:200 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product Details
MA5-55378
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
2Z9F3
Immunogen
Recombinant fusion protein containing a sequen cecorresponding to amino acids 50-174 of human ADAMTS1.
Conjugate
Form
Liquid
Concentration
1.78 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
Immunogen Sequence: LGRPSEEDEE LVVPELERAP GHGTTRLRLH AFDQQLDLEL RPDSSFLAPG FTLQNVGRKS GSETPLPETD LAHCFYSGTV NGDPSSAAAL SLCEGVRGAF YLLGEAYFIQ PLPAASERLA TAAPG
Target Information
ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS-1); a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metallopeptidse (reprolysin type) with thrombospondin type 1 motif, 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 1; ADAM-TS 1; ADAM-TS1; ADAMs; ADAMTS-1; human metalloproteinase with thrombospondin type 1 motifs; metalloendopeptidases; METH-1
Gene Aliases: ADAM-TS1; ADAMTS; ADAMTS-1; ADAMTS1; C3-C5; KIAA1346; METH-1; METH1
UniProt ID: (Human) Q9UHI8, (Mouse) P97857
Entrez Gene ID: (Human) 9510, (Mouse) 11504, (Rat) 79252
ovulation from ovarian follicle
kidney development
proteolysis
integrin-mediated signaling pathway
negative regulation of cell proliferation
positive regulation of neuron projection development
tooth eruption
heart trabecula formation
cellular response to vitamin D
cellular response to parathyroid hormone stimulus
cellular response to prostaglandin E stimulus
negative regulation of angiogenesis
ovulation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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