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ADAMTS15 Antibody (PA5-48070) in IHC (P)
Immunohistochemical analysis of ADAMTS15 in immersion fixed paraffin-embedded sections of human breast cancer tissue. Samples were incubated in ADAMTS15 polyclonal antibody (Product # PA5-48070) using a dilution of 3 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic. Tissue was stained using the ... View More
Product Details
PA5-48070
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHO-derived recombinant human ADAMTS15 Gly18-Cys682
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606415
Product Specific Information
In direct ELISAs, less than 1% cross-reactivity with recombinant human ADAMTS1, L1.2, L2, 3, 4, 5, 8, 10, 12, 13, and 16 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. The ADAMTS proteases function in processing of procollagens and von Willebrand factor as well as catabolism of aggrecan, versican and brevican. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The immunizing peptide sequence is 100% conserved between human, mouse and rat.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 15; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15, preproprotein; ADAM; ADAM-TS 15; ADAM-TS15; ADAMs; ADAMTS-15; metalloendopeptidases; metalloprotease disintegrin 15 with thrombospondin domains
Gene Aliases: ADAMTS15
UniProt ID: (Human) Q8TE58, (Mouse) P59384
Entrez Gene ID: (Human) 170689, (Mouse) 235130
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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