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Product Details
PA5-54390
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ADAMTS3. Recombinant protein control fragment (Product #RP-93163).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2637668
Product Specific Information
Immunogen sequence: KPDGANLRQR SAQQAGSKTV RLVTVPSSPP TKRVHLSSAS QMAAASFFAA SDSIGASSQA RTSKKDGKII D
Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 30%.
Target Information
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 3; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 3; ADAM-TS 3; ADAM-TS3; ADAMs; ADAMTS-3; metalloendopeptidases; PC II-NP; Procollagen II amino propeptide-processing enzyme; Procollagen II N-proteinase; zinc metalloendopeptidase
Gene Aliases: ADAMTS-4; ADAMTS3; KIAA0366
UniProt ID: (Human) O15072
Entrez Gene ID: (Human) 9508
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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