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Product Details
PA5-53290
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ADCY10. Recombinant protein control fragment (Product #RP-90979).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2637692
Product Specific Information
Immunogen sequence: NLENLVAQNT TGPVFCPRLY HLMAYVCILM GDGQKCGLFL NTALRLSETQ GNILEKCWLN MNKESWYSTS ELKEDQWLQT ILSLPSW
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 80%.
Target Information
SAC belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction.The protein encoded by this gene belongs to a distinct class of mammalian adenylyl cyclase that is soluble and insensitive to G protein or forskolin regulation. It is localized in the cytoplasm and is thought to function as a general bicarbonate sensor throughout the body. It may also play an important role in the generation of cAMP in spermatozoa, implying possible roles in sperm maturation through the epididymis, capacitation, hypermotility, and/or the acrosome reaction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3',5'-cyclic AMP synthetase; adenylate cyclase 10 (soluble); Adenylate cyclase homolog; Adenylate cyclase type 10; AH-related protein; ATP pyrophosphate-lyase; epididymis secretory sperm binding protein Li 7a; Germ cell soluble adenylyl cyclase; hsAC; RP1-313L4.2; Testicular soluble adenylyl cyclase; testicular soluble adenylyl cyclase (SAC)
Gene Aliases: ADCY10; HCA2; HEL-S-7a; hsAC; SAC; SACI; Sacy
UniProt ID: (Human) F5GWS5
Entrez Gene ID: (Human) 55811
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