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Product Details
BS-3925R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human ADCY8, amino acids 151-250.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AC8; adenylate cyclase 8 (brain); Adenylate cyclase type 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; adenylyl cyclase-8, brain; ATP pyrophosphate-lyase 8; Ca(2+)/calmodulin-activated adenylyl cyclase; epididymis secretory sperm binding protein Li 172mP; HEL-S-172mP; type VIII adenylyl cyclase
Gene Aliases: AC8; ADCY3; ADCY8; AW060868; HBAC1
UniProt ID: (Human) P40145, (Rat) P40146, (Mouse) P97490
Entrez Gene ID: (Human) 114, (Rat) 29241, (Mouse) 11514
cAMP biosynthetic process
adenylate cyclase-activating G-protein coupled receptor signaling pathway
long-term memory
response to organic cyclic compound
cAMP-mediated signaling
intracellular signal transduction
cellular response to calcium ion
cyclic nucleotide biosynthetic process
renal water homeostasis
signal transduction
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
learning or memory
activation of protein kinase A activity
cellular response to glucagon stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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