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Product Details
PA5-120981
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 168-437 of human Perilipin-2 (NP_0011132)
Conjugate
Form
Liquid
Concentration
0.54 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914553
Product Specific Information
Positive test controls include: HepG2, NIH/3T3, Mouse brain, Rat heart. The target is usually found in the following locations: Membrane, Peripheral membrane protein.
Immunogen sequence: MMQLVSSGVE NALTKSELLV EQYLPLTEEE LEKEAKKVEG FDLVQKPSYY VRLGSLSTKL HSRAYQQALS RVKEAKQKSQ QTISQLHSTV HLIEFARKNV YSANQKIQDA QDKLYLSWVE WKRSIGYDDT DESHCAEHIE SRTLAIARNL TQQLQTTCHT LLSNIQGVPQ NIQDQAKHMG VMAGDIYSVF RNAASFKEVS DSLLTSSKGQ LQKMKESLDD VMDYLVNNTP LNWLVGPFYP QLTESQNAQD QGAEMDKSSQ ETQRSEHKTH
Target Information
Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adipophilin; adipose differentiation related protein; Adipose differentiation-related protein; ADRP; ADRP antibody; MGC10598; Perilipin-2
Gene Aliases: AA407157; ADFP; ADPH; ADRP; PLIN2
UniProt ID: (Human) Q99541, (Mouse) P43883
Entrez Gene ID: (Human) 123, (Mouse) 11520, (Rat) 298199
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