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ADH7 Antibody (PA5-98484) in WB
Western Blot analysis of ADH7 using a ADH7 Polyclonal antibody (Product # PA5-98484) at a concentration of 3.5 µg/mL. Positive WB detected in: Mouse liver tissue. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 40 kDa.
Product Details
PA5-98484
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Mouse Alcohol dehydrogenase class 4 mu/sigma chain protein (1-374AA)
Conjugate
Form
Liquid
Concentration
3.5 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2813097
Target Information
This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The enzyme encoded by this gene is inefficient in ethanol oxidation, but is the most active as a retinol dehydrogenase; thus it may participate in the synthesis of retinoic acid, a hormone important for cellular differentiation. The expression of this gene is much more abundant in stomach than liver, thus differing from the other known gene family members.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADH-C2; alcohol dehydrogenase 3 complex; alcohol dehydrogenase 3 temporal; alcohol dehydrogenase 4; Alcohol dehydrogenase 7; Alcohol dehydrogenase class 4 mu/sigma chain; Alcohol dehydrogenase class IV mu/sigma chain; All-trans-retinol dehydrogenase [NAD(+)] ADH7; Gastric alcohol dehydrogenase; IV ADH; Omega-hydroxydecanoate dehydrogenase ADH7; ret; Retinol dehydrogenase
Gene Aliases: Adh-3; Adh-3e; Adh-3t; Adh3; Adh3-e; Adh3-t; Adh4; Adh7; Adt-1; AI325182
UniProt ID: (Mouse) Q64437
Entrez Gene ID: (Mouse) 11529
alcohol dehydrogenase (NAD) activity
alcohol dehydrogenase activity, zinc-dependent
aldehyde oxidase activity
retinol dehydrogenase activity
zinc ion binding
oxidoreductase activity
retinol binding
ethanol binding
protein homodimerization activity
metal ion binding
receptor antagonist activity
NAD binding
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
retinoid metabolic process
ethanol metabolic process
ethanol catabolic process
ethanol oxidation
response to bacterium
fatty acid omega-oxidation
retinol metabolic process
retinoic acid metabolic process
response to ethanol
oxidation-reduction process
extracellular negative regulation of signal transduction
negative regulation of receptor activity
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