Proteintech

AEBP2 Polyclonal Antibody

FIGURE: 1 / 3

AEBP2 Antibody (11232-2-AP) in WB

Human testis tissue were subjected to SDS PAGE followed by western blot with 11232-2-AP (AEBP2 antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours.

AEBP2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

11232-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 3 publications 3 publications

Immunoprecipitation (IP)

0.5-4.0 µg

ChIP assay (ChIP)

Assay-dependent

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

AEBP2 Fusion Protein Ag1756 (1-295 aa encoded by BC015624)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.26 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSSDGEPLS RMDSEDSISS TIMDVDSTIS SGRSTPAMMN GQGSTTSSSK NIAYNCCWDQ CQACFNSSPD LADHIRSIHV DGQRGGVFVC LWKGCKVYNT PSTSQSWLQR HMLTHSGDKP FKCVVGGCNA SFASQGGLAR HVPTHFSQQN SSKVSSQPKA KEESPSKAGM NKRRKLKNKR RRSLPRPHDF FDAQTLDAIR HRAICFNLSA HIESLGKGHS VVFHSTVIAK RKEDSGKIKL LLHWMPEDIL PDVWVNESER HQLKTKVVHL SKLPKDTALL LDPNIYRTMP QKRLKR (1-295 aa encoded by B C015624)

Target Information

AEBP2 is a DNA-binding transcriptional repressor. It may interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Alu elements in ANRIL non-coding RNA at chromosome 9p21 modulate atherogenic cell functions through trans-regulation of gene networks.

PLoS genetics

Holdt LM,Hoffmann S,Sass K,Langenberger D,Scholz M,Krohn K,Finstermeier K,Stahringer A,Wilfert W,Beutner F,Gielen S,Schuler G,Gäbel G,Bergert H,Bechmann I,Stadler PF,Thiery J,Teupser D

Wed Jan 08 00:00:00 EST 2014

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.

Nature

Wu H,D'Alessio AC,Ito S,Xia K,Wang Z,Cui K,Zhao K,Sun YE,Zhang Y

Thu May 19 00:00:00 EDT 2011

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.

Nature

Wu H,D'Alessio AC,Ito S,Xia K,Wang Z,Cui K,Zhao K,Sun YE,Zhang Y

Thu May 19 00:00:00 EDT 2011

Aebp2 as an epigenetic regulator for neural crest cells.

PloS one

Kim H,Kang K,Ekram MB,Roh TY,Kim J

Fri Feb 03 00:00:00 EST 2012

Aebp2 as an epigenetic regulator for neural crest cells.

PloS one

Kim H,Kang K,Ekram MB,Roh TY,Kim J

Fri Feb 03 00:00:00 EST 2012

AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.

Nucleic acids research

Kim H,Kang K,Kim J

Fri May 01 00:00:00 EDT 2009

AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.

Nucleic acids research

Kim H,Kang K,Kim J

Fri May 01 00:00:00 EDT 2009

AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.

Nucleic acids research

Kim H,Kang K,Kim J

Fri May 01 00:00:00 EDT 2009

AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.

Nucleic acids research

Kim H,Kang K,Kim J

Fri May 01 00:00:00 EDT 2009

Bioinformatics

Protein Aliases: Adipocyte enhancer-binding protein 2; AE(adipocyte enhancer)-binding protein 2; AE-binding protein 2; Zinc finger protein AEBP2

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Gene Aliases: AEBP2; AU023766; B230313N05Rik

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UniProt ID: (Human) Q6ZN18, (Mouse) Q9Z248

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Entrez Gene ID: (Human) 121536, (Rat) 297705, (Mouse) 11569

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Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription corepressor activity metal ion binding DNA binding nucleic acid binding

Process(es)

negative regulation of transcription from RNA polymerase II promoter regulation of transcription, DNA-templated transcription from RNA polymerase II promoter transcription, DNA-templated chromatin modification covalent chromatin modification negative regulation of gene expression, epigenetic

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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AEBP2 Polyclonal Antibody

AEBP2 Antibody (11232-2-AP) in WB

Product Details

11232-2-AP

Western Blot (WB)

Immunoprecipitation (IP)

ChIP assay (ChIP)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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