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The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.
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Protein Aliases: AF4/FMR2 family member 4; AF4/FMR2 family, member 4; ALL1 fused gene from 5q31; ALL1-fused gene from chromosome 5q31 protein; Major CDK9 elongation factor-associated protein; Protein AF-5q31
Gene Aliases: AF5Q31; AFF4; Alf4; CHOPS; HSPC092; Laf4l; MCEF
UniProt ID: (Human) Q6P592, (Mouse) Q9ESC8
Entrez Gene ID: (Human) 27125, (Rat) 303132, (Mouse) 93736
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