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Immunogen sequence: LGNYDEMKDF IGDRSIPKLV AIPKPTVPPS ADEKSNPNFF EQRHGGSHQS SKWTPVGPAP STSQSQKRSS GLQSGHSSQR TSAGSSSGTN SSGQRHDRES YNNSGSSSRK KGQHGSEHSK SRSSSPGKPQ AVSSLNSSHS RSHG
The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins.
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Protein Aliases: AF4/FMR2 family member 4; AF4/FMR2 family, member 4; ALL1-fused gene from chromosome 5q31 protein; Major CDK9 elongation factor-associated protein; Protein AF-5q31
Gene Aliases: AF5Q31; AFF4; CHOPS; HSPC092; MCEF
UniProt ID: (Human) Q6P592
Entrez Gene ID: (Human) 27125
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