Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Store vial at 4° C prior to restoration. For extended storage aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This protein A purified antibody is directed against human AGAP2 protein. A BLAST analysis was used to suggest cross reactivity with AGAP2 protein from mouse and rat based on 93% and 95% protein:protein homologies, respectively, with the immunizing sequence. Reactivity against homologues from other sources is not known.
The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AGAP-2; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; centaurin gamma1; centaurin, gamma 1; Centaurin-gamma-1; Cnt-g1; FLJ16430; GGAP2; GTP-binding and GTPase activating protein 2; GTP-binding and GTPase-activating protein 2; Phosphatidylinositol 3-kinase enhancer; phosphatidylinositol-3-kinase enhancer; phosphoinositide 3-kinase enhancer; PIKE
Gene Aliases: AGAP-2; AGAP2; CENTG1; cnt-g1; GGAP2; KIAA0167; mKIAA0167; PIKE
UniProt ID: (Human) Q99490, (Mouse) Q3UHD9
Entrez Gene ID: (Human) 116986, (Mouse) 216439
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