Product References
Association between AHR Expression and Immune Dysregulation in Pancreatic Ductal Adenocarcinoma: Insights from Comprehensive Immune Profiling of Peripheral Blood Mononuclear Cells.
Cancers
Bartkeviciene A,Jasukaitiene A,Zievyte I,Stukas D,Ivanauskiene S,Urboniene D,Maimets T,Jaudzems K,Vitkauskiene A,Matthews J,Dambrauskas Z,Gulbinas A
Published figure using AHR monoclonal antibody (Product # MA1-514) in Western Blot
Tue Sep 19 00:00:00 EDT 2023
Microglial aryl hydrocarbon receptor enhances phagocytic function via SYK and promotes remyelination in the cuprizone mouse model of demyelination.
Journal of neuroinflammation
Wang Y,Sun J,Zhu K,Wang D,Zhao X,Zhang H,Wu S,Wang Y,Wang J
MA1-514 was used in ChIP assay to highlight an essential role for AhR in microglial phagocytic function and suggests the therapeutic potential of AhR in demyelinating diseases.
Sat Mar 25 00:00:00 EDT 2023
Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy.
The Journal of clinical investigation
van de Veerdonk FL,Renga G,Pariano M,Bellet MM,Servillo G,Fallarino F,De Luca A,Iannitti RG,Piobbico D,Gargaro M,Manni G,D'Onofrio F,Stincardini C,Sforna L,Borghi M,Castelli M,Pieroni S,Oikonomou V,Villella VR,Puccetti M,Giovagnoli S,Galarini R,Barola C,Maiuri L,Della Fazia MA,Cellini B,Talesa VN,Dinarello CA,Costantini C,Romani L
Published figure using AHR monoclonal antibody (Product # MA1-514) in Immunoprecipitation
Tue Jan 18 00:00:00 EST 2022
Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy.
The Journal of clinical investigation
van de Veerdonk FL,Renga G,Pariano M,Bellet MM,Servillo G,Fallarino F,De Luca A,Iannitti RG,Piobbico D,Gargaro M,Manni G,D'Onofrio F,Stincardini C,Sforna L,Borghi M,Castelli M,Pieroni S,Oikonomou V,Villella VR,Puccetti M,Giovagnoli S,Galarini R,Barola C,Maiuri L,Della Fazia MA,Cellini B,Talesa VN,Dinarello CA,Costantini C,Romani L
Published figure using AHR monoclonal antibody (Product # MA1-514) in Immunoprecipitation
Tue Jan 18 00:00:00 EST 2022
Kynurenine/Aryl Hydrocarbon Receptor Modulates Mitochondria-Mediated Oxidative Stress and Neuronal Apoptosis in Experimental Intracerebral Hemorrhage.
Antioxidants & redox signaling
Ren R,Fang Y,Sherchan P,Lu Q,Lenahan C,Zhang JH,Zhang J,Tang J
Published figure using AHR monoclonal antibody (Product # MA1-514) in Western Blot
Thu Dec 01 00:00:00 EST 2022
Intestinal Osteopontin Protects From Alcohol-induced Liver Injury by Preserving the Gut Microbiome and the Intestinal Barrier Function.
Cellular and molecular gastroenterology and hepatology
Das S,Song Z,Han H,Ge X,Desert R,Athavale D,Babu Komakula SS,Magdaleno F,Chen W,Lantvit D,Guzman G,Nieto N
MA1-514 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to demonstrate that Opn-/- develop worse alcohol-associated liver disease than wild-type (WT) mice.
Mon Sep 26 00:00:00 EDT 2022
Intestinal Osteopontin Protects From Alcohol-induced Liver Injury by Preserving the Gut Microbiome and the Intestinal Barrier Function.
Cellular and molecular gastroenterology and hepatology
Das S,Song Z,Han H,Ge X,Desert R,Athavale D,Babu Komakula SS,Magdaleno F,Chen W,Lantvit D,Guzman G,Nieto N
MA1-514 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to demonstrate that Opn-/- develop worse alcohol-associated liver disease than wild-type (WT) mice.
Mon Sep 26 00:00:00 EDT 2022
Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D.
Nature communications
Kim YS,Ko B,Kim DJ,Tak J,Han CY,Cho JY,Kim W,Kim SG
MA1-514 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to reveal that AhR induction by alcohol inhibits autophagy in hepatocytes through AMPKα, which is mediated by Ppp2r2d gene transactivation, revealing an AhR-dependent metabolism of phospho-/sphingo-lipids.
Fri Oct 14 00:00:00 EDT 2022
Impact of Epithelial-Mesenchymal Immunophenotype on Local Aggressiveness in Papillary Thyroid Carcinoma Invading the Airway.
Journal of clinical medicine
Mandarano M,Andolfi M,Colella R,Monacelli M,Polistena A,Moretti S,Bellezza G,Puxeddu E,Sanguinetti A,Sidoni A,Avenia N,Puma F,Vannucci J
MA1-514 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to evaluate the prognostic role of E-cadherin, N-cadherin, Aryl hydrocarbon receptor (AhR), and CD147 in different biological behaviours.
Fri Sep 24 00:00:00 EDT 2021
Impact of Epithelial-Mesenchymal Immunophenotype on Local Aggressiveness in Papillary Thyroid Carcinoma Invading the Airway.
Journal of clinical medicine
Mandarano M,Andolfi M,Colella R,Monacelli M,Polistena A,Moretti S,Bellezza G,Puxeddu E,Sanguinetti A,Sidoni A,Avenia N,Puma F,Vannucci J
MA1-514 was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to evaluate the prognostic role of E-cadherin, N-cadherin, Aryl hydrocarbon receptor (AhR), and CD147 in different biological behaviours.
Fri Sep 24 00:00:00 EDT 2021
Tomato and Olive Bioactive Compounds: A Natural Shield against the Cellular Effects Induced by β-Hexachlorocyclohexane-Activated Signaling Pathways.
Molecules (Basel, Switzerland)
Rubini E,Minacori M,Paglia G,Macone A,Chichiarelli S,Altieri F,Eufemi M
Published figure using AHR monoclonal antibody (Product # MA1-514) in Immunocytochemistry
Thu Nov 25 00:00:00 EST 2021
AHR is a Zika virus host factor and a candidate target for antiviral therapy.
Nature neuroscience
Giovannoni F,Bosch I,Polonio CM,Torti MF,Wheeler MA,Li Z,Romorini L,Rodriguez Varela MS,Rothhammer V,Barroso A,Tjon EC,Sanmarco LM,Takenaka MC,Modaresi SMS,Gutiérrez-Vázquez C,Zanluqui NG,Dos Santos NB,Munhoz CD,Wang Z,Damonte EB,Sherr D,Gehrke L,Peron JPS,Garcia CC,Quintana FJ
MA1-514 was used in Western Blotting to identify AHR as a host factor for ZIKV replication and PML protein as a driver of anti-ZIKV intrinsic immunity.
Sat Aug 01 00:00:00 EDT 2020
Night Cream Containing Melatonin, Carnosine and Helichrysum italicum Extract Helps Reduce Skin Reactivity and Signs of Photodamage: Ex Vivo and Clinical Studies.
Dermatology and therapy
Granger C,Brown A,Aladren S,Narda M
MA1-514 was used in Immunohistochemistry to determine the ability of a night cream containing melatonin, carnosine and Helichrysum italicum extract (referred to here as Night Cream) to reduce extrinsic skin damage, and to evaluate the efficacy of this Night Cream to reduce clinical signs of age and photodamage under normal conditions of use.
Tue Dec 01 00:00:00 EST 2020
β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry.
Biomedicines
Rubini E,Paglia G,Cannella D,Macone A,Di Sotto A,Gullì M,Altieri F,Eufemi M
MA1-514 was used in Western Blot, Immunocytochemistry to provide further elements to draw the biochemical profile of this organochlorine pesticides.
Mon Nov 16 00:00:00 EST 2020
β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry.
Biomedicines
Rubini E,Paglia G,Cannella D,Macone A,Di Sotto A,Gullì M,Altieri F,Eufemi M
MA1-514 was used in Western Blot, Immunocytochemistry to provide further elements to draw the biochemical profile of this organochlorine pesticides.
Mon Nov 16 00:00:00 EST 2020
β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry.
Biomedicines
Rubini E,Paglia G,Cannella D,Macone A,Di Sotto A,Gullì M,Altieri F,Eufemi M
MA1-514 was used in Western Blot, Immunocytochemistry to provide further elements to draw the biochemical profile of this organochlorine pesticides.
Mon Nov 16 00:00:00 EST 2020
β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry.
Biomedicines
Rubini E,Paglia G,Cannella D,Macone A,Di Sotto A,Gullì M,Altieri F,Eufemi M
MA1-514 was used in Western Blot, Immunocytochemistry to provide further elements to draw the biochemical profile of this organochlorine pesticides.
Mon Nov 16 00:00:00 EST 2020
Aryl Hydrocarbon Receptor in Post-Mortem Hippocampus and in Serum from Young, Elder, and Alzheimer's Patients.
International journal of molecular sciences
Ramos-García NA,Orozco-Ibarra M,Estudillo E,Elizondo G,Gómez Apo E,Chávez Macías LG,Sosa-Ortiz AL,Torres-Ramos MA
Published figure using AHR monoclonal antibody (Product # MA1-514) in Immunohistochemistry
Sat Mar 14 00:00:00 EDT 2020
Aryl Hydrocarbon Receptor in Post-Mortem Hippocampus and in Serum from Young, Elder, and Alzheimer's Patients.
International journal of molecular sciences
Ramos-García NA,Orozco-Ibarra M,Estudillo E,Elizondo G,Gómez Apo E,Chávez Macías LG,Sosa-Ortiz AL,Torres-Ramos MA
Published figure using AHR monoclonal antibody (Product # MA1-514) in Immunohistochemistry
Sat Mar 14 00:00:00 EDT 2020
Aryl Hydrocarbon Receptor in Post-Mortem Hippocampus and in Serum from Young, Elder, and Alzheimer's Patients.
International journal of molecular sciences
Ramos-García NA,Orozco-Ibarra M,Estudillo E,Elizondo G,Gómez Apo E,Chávez Macías LG,Sosa-Ortiz AL,Torres-Ramos MA
Published figure using AHR monoclonal antibody (Product # MA1-514) in Immunohistochemistry
Sat Mar 14 00:00:00 EDT 2020
Parkin is transcriptionally regulated by the aryl hydrocarbon receptor: Impact on α-synuclein protein levels.
Biochemical pharmacology
González-Barbosa E,García-Aguilar R,Vega L,Cabañas-Cortés MA,Gonzalez FJ,Segovia J,Morales-Lázaro SL,Cisneros B,Elizondo G
MA1-514 was used in Chromatin immunoprecipitation to suggest that treatments designed to induce PRKN expression through the use of nontoxic AhR agonist ligands may be novel strategies to prevent and delay PD.
Tue Oct 01 00:00:00 EDT 2019
Identification of the novel role of butyrate as AhR ligand in human intestinal epithelial cells.
Scientific reports
Marinelli L,Martin-Gallausiaux C,Bourhis JM,Béguet-Crespel F,Blottière HM,Lapaque N
MA1-514 was used in Western Blotting to show that butyrate activates the AhR pathway and AhR-dependent genes in human intestinal epithelial cell lines as well as, butyrate being a potential ligand for AhR which is an original mechanism of gene regulation by SCFA.
Thu Jan 24 00:00:00 EST 2019
Towards Resolving the Pro- and Anti-Tumor Effects of the Aryl Hydrocarbon Receptor.
International journal of molecular sciences
Narasimhan S,Stanford Zulick E,Novikov O,Parks AJ,Schlezinger JJ,Wang Z,Laroche F,Feng H,Mulas F,Monti S,Sherr DH
MA1-514 was used in Western Blotting to elucidate both the pro- and anti-tumour effects of the aryl hydrocarbon receptor.
Mon May 07 00:00:00 EDT 2018
Aryl Hydrocarbon Receptor Promotes Liver Polyploidization and Inhibits PI3K, ERK, and Wnt/β-Catenin Signaling.
iScience
Moreno-Marín N,Merino JM,Alvarez-Barrientos A,Patel DP,Takahashi S,González-Sancho JM,Gandolfo P,Rios RM,Muñoz A,Gonzalez FJ,Fernández-Salguero PM
MA1-514 was used in Immunoprecipitation to study the role of aryl hydrocarbon receptor in the regulation of polyploidisation during the preweaning-to-adult mouse liver maturation.
Fri Jun 29 00:00:00 EDT 2018
Dioxins and related environmental contaminants increase TDP-43 levels.
Molecular neurodegeneration
Ash PEA,Stanford EA,Al Abdulatif A,Ramirez-Cardenas A,Ballance HI,Boudeau S,Jeh A,Murithi JM,Tripodis Y,Murphy GJ,Sherr DH,Wolozin B
MA1-514 was used in Western Blotting to suggest that environmental dioxin induced aryl hydrocarbon receptor activation increases ALS pathological protein TDP-43 concentration in human neuronal cell lines and mouse brain.
Fri May 05 00:00:00 EDT 2017
piRNA-associated proteins and retrotransposons are differentially expressed in murine testis and ovary of aryl hydrocarbon receptor deficient mice.
Open biology
Rico-Leo EM,Moreno-Marín N,González-Rico FJ,Barrasa E,Ortega-Ferrusola C,Martín-Muñoz P,Sánchez-Guardado LO,Llano E,Alvarez-Barrientos A,Infante-Campos A,Catalina-Fernández I,Hidalgo-Sánchez M,de Rooij DG,Pendás AM,Peña FJ,Merino JM,Fernández-Salguero PM
MA1514 was used in immunohistochemistry to discover that the aryl hydrocarbon receptor regulates the general course of spermatogenesis and oogenesis by a mechanism likely to be associated with Piwi-interacting RNA-associated proteins, Piwi-interacting RNAs and retrotransposons
Thu Dec 01 00:00:00 EST 2016
piRNA-associated proteins and retrotransposons are differentially expressed in murine testis and ovary of aryl hydrocarbon receptor deficient mice.
Open biology
Rico-Leo EM,Moreno-Marín N,González-Rico FJ,Barrasa E,Ortega-Ferrusola C,Martín-Muñoz P,Sánchez-Guardado LO,Llano E,Alvarez-Barrientos A,Infante-Campos A,Catalina-Fernández I,Hidalgo-Sánchez M,de Rooij DG,Pendás AM,Peña FJ,Merino JM,Fernández-Salguero PM
MA1514 was used in immunohistochemistry to discover that the aryl hydrocarbon receptor regulates the general course of spermatogenesis and oogenesis by a mechanism likely to be associated with Piwi-interacting RNA-associated proteins, Piwi-interacting RNAs and retrotransposons
Thu Dec 01 00:00:00 EST 2016
Notch-regulated miR-223 targets the aryl hydrocarbon receptor pathway and increases cytokine production in macrophages from rheumatoid arthritis patients.
Scientific reports
Ogando J,Tardáguila M,Díaz-Alderete A,Usategui A,Miranda-Ramos V,Martínez-Herrera DJ,de la Fuente L,García-León MJ,Moreno MC,Escudero S,Cañete JD,Toribio ML,Cases I,Pascual-Montano A,Pablos JL,Mañes S
MA1514 was used in western blot to identify miR-223 as a negative regulator of the aryl hydrocarbon receptor/aryl hydrocarbon receptor translocator pathway
Wed Feb 03 00:00:00 EST 2016
Detrusor induction of miR-132/212 following bladder outlet obstruction: association with MeCP2 repression and cell viability.
PloS one
Sadegh MK,Ekman M,Krawczyk K,Svensson D,Göransson O,Dahan D,Nilsson BO,Albinsson S,Uvelius B,Swärd K
Published figure using AHR monoclonal antibody (Product # MA1-514) in Immunofluorescence
Tue Jan 05 00:00:00 EST 2016
Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down.
Journal of dermatological science
Forrester AR,Elias MS,Woodward EL,Graham M,Williams FM,Reynolds NJ
MA1-514 was used in western blot to study the role of aryl hydrocarbon receptor activation in chloracne induction by TCDD in a human epidermal equivalent model
Wed Jan 01 00:00:00 EST 2014
Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down.
Journal of dermatological science
Forrester AR,Elias MS,Woodward EL,Graham M,Williams FM,Reynolds NJ
MA1-514 was used in western blot to study the role of aryl hydrocarbon receptor activation in chloracne induction by TCDD in a human epidermal equivalent model
Wed Jan 01 00:00:00 EST 2014
HER2 overexpression-mediated inflammatory signaling enhances mammosphere formation through up-regulation of aryl hydrocarbon receptor transcription.
Cancer letters
Zhao S,Ohara S,Kanno Y,Midorikawa Y,Nakayama M,Makimura M,Park Y,Inouye Y
MA1-514 was used in western blot to study the role of HER2-aryl hydrocarbon receptor interactions in mammosphere formation in MCF-7 breast cancer cells
Fri Mar 01 00:00:00 EST 2013
Aryl hydrocarbon receptor regulates the cholesterol biosynthetic pathway in a dioxin response element-independent manner.
Hepatology (Baltimore, Md.)
Tanos R,Patel RD,Murray IA,Smith PB,Patterson AD,Perdew GH
MA1-514 was used in western blot to investigate the role of aryl hydrocarbon receptor in cholesterol biosynthetic pathway
Fri Jun 01 00:00:00 EDT 2012
Activation of the aryl hydrocarbon receptor represses mammosphere formation in MCF-7 cells.
Cancer letters
Zhao S,Kanno Y,Nakayama M,Makimura M,Ohara S,Inouye Y
MA1-514 was used in western blot to study the suppression of mammosphere formation in MCF-7 cells by aryl hydrocarbon receptor activation
Sat Apr 28 00:00:00 EDT 2012
Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch.
Genome research
Román AC,González-Rico FJ,Moltó E,Hernando H,Neto A,Vicente-Garcia C,Ballestar E,Gómez-Skarmeta JL,Vavrova-Anderson J,White RJ,Montoliu L,Fernández-Salguero PM
MA1-514 was used in ChIP assay to investigate the role of dioxin receptor in the insulator activity of B1-X35S retrotransposon
Tue Mar 01 00:00:00 EST 2011
Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch.
Genome research
Román AC,González-Rico FJ,Moltó E,Hernando H,Neto A,Vicente-Garcia C,Ballestar E,Gómez-Skarmeta JL,Vavrova-Anderson J,White RJ,Montoliu L,Fernández-Salguero PM
MA1-514 was used in ChIP assay to investigate the role of dioxin receptor in the insulator activity of B1-X35S retrotransposon
Tue Mar 01 00:00:00 EST 2011
Maternal smoking and fetal sex significantly affect metabolic enzyme expression in the human fetal liver.
The Journal of clinical endocrinology and metabolism
O'Shaughnessy PJ,Monteiro A,Bhattacharya S,Fowler PA
MA1-514 was used in western blot to study the effects of maternal smoking and fetal sex on metabolic enzyme expression in the fetal liver
Thu Sep 01 00:00:00 EDT 2011
Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone.
The Journal of pharmacology and experimental therapeutics
Murray IA,Flaveny CA,DiNatale BC,Chairo CR,Schroeder JC,Kusnadi A,Perdew GH
MA1-514 was used in western blot to investigate the effect of 6,2',4'-trimethoxyflavone for aryl hydrocarbon receptor signaling activity
Fri Jan 01 00:00:00 EST 2010
Suppression mechanisms of flavonoids on aryl hydrocarbon receptor-mediated signal transduction.
Archives of biochemistry and biophysics
Mukai R,Shirai Y,Saito N,Fukuda I,Nishiumi S,Yoshida K,Ashida H
MA1-514 was used in western blot to investigate the mechanisms by which flavonoids suppress the AhR-mediated signal transduction in mouse hepatoma Hepa-1c1c7 cells
Wed Sep 01 00:00:00 EDT 2010
Differential gene regulation by the human and mouse aryl hydrocarbon receptor.
Toxicological sciences : an official journal of the Society of Toxicology
Flaveny CA,Murray IA,Perdew GH
MA1-514 was used in western blot to characterize mouse vs. human divergence in receptor-regulated gene expression
Thu Apr 01 00:00:00 EDT 2010
Evidence for ligand-mediated selective modulation of aryl hydrocarbon receptor activity.
Molecular pharmacology
Murray IA,Morales JL,Flaveny CA,Dinatale BC,Chiaro C,Gowdahalli K,Amin S,Perdew GH
MA1-514 was used in western blot to study the regulation of Aryl hydrocarbon receptor activity and its anti-inflammatory therapeutic potential
Mon Feb 01 00:00:00 EST 2010
Inhibition of P-glycoprotein enhances the suppressive effect of kaempferol on transformation of the aryl hydrocarbon receptor.
Bioscience, biotechnology, and biochemistry
Mukai R,Satsu H,Shimizu M,Ashida H
MA1-514 was used in ELISA to investigate the role of P-glycoprotein for supression on transformation of the aryl hydrocarbon receptor by kaempferol
Wed Jul 01 00:00:00 EDT 2009
Genome-wide B1 retrotransposon binds the transcription factors dioxin receptor and Slug and regulates gene expression in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Roman AC,Benitez DA,Carvajal-Gonzalez JM,Fernandez-Salguero PM
MA1-514 was used in ChIP assay to investigate the role of genome-wide B1 retrotransposon on regulates gene expression in vivo
Tue Feb 05 00:00:00 EST 2008
Genome-wide B1 retrotransposon binds the transcription factors dioxin receptor and Slug and regulates gene expression in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Roman AC,Benitez DA,Carvajal-Gonzalez JM,Fernandez-Salguero PM
MA1-514 was used in ChIP assay to investigate the role of genome-wide B1 retrotransposon on regulates gene expression in vivo
Tue Feb 05 00:00:00 EST 2008
Genome-wide B1 retrotransposon binds the transcription factors dioxin receptor and Slug and regulates gene expression in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Roman AC,Benitez DA,Carvajal-Gonzalez JM,Fernandez-Salguero PM
MA1-514 was used in ChIP assay to investigate the role of genome-wide B1 retrotransposon on regulates gene expression in vivo
Tue Feb 05 00:00:00 EST 2008
Omeprazole stimulates the induction of human insulin-like growth factor binding protein-1 through aryl hydrocarbon receptor activation.
The Journal of pharmacology and experimental therapeutics
Murray IA,Perdew GH
Published figure using AHR monoclonal antibody (Product # MA1-514) in Western Blot
Sat Mar 01 00:00:00 EST 2008
The mouse and human Ah receptor differ in recognition of LXXLL motifs.
Archives of biochemistry and biophysics
Flaveny C,Reen RK,Kusnadi A,Perdew GH
MA1-514 was used in Western Blot to study the differential recognition of LXXLL-motif coactivators by human and mouse aryl hydrocarbon receptors.
Sat Mar 15 00:00:00 EDT 2008
Characterization of the antiallergic drugs 3-[2-(2-phenylethyl) benzoimidazole-4-yl]-3-hydroxypropanoic acid and ethyl 3-hydroxy-3-[2-(2-phenylethyl)benzoimidazol-4-yl]propanoate as full aryl hydrocarbon receptor agonists.
Chemical research in toxicology
Morales JL,Krzeminski J,Amin S,Perdew GH
MA1-514 was used in Western Blotting to synthesise and evaluate the ability of 3-[2-(2-phenylethyl) benzoimidazole-4-yl]-3-hydroxypropanoic acid and ethyl 3-hydroxy-3-[2-(2-phenylethyl)benzoimidazol-4-yl]propanoate to regulate aryl hydrocarbon receptor activity.
Fri Feb 01 00:00:00 EST 2008
Differentiation-specific factors modulate epidermal CYP1-4 gene expression in human skin in response to retinoic acid and classic aryl hydrocarbon receptor ligands.
The Journal of pharmacology and experimental therapeutics
Du L,Neis MM,Ladd PA,Keeney DS
MA1-514 was used in western blot to investigate the change of CYP1-4 gene expression in differentiating epidermal cells exposed to drug compounds related to clinical dermatology practice or foreign compounds affecting normal epidermal differentiation
Fri Dec 01 00:00:00 EST 2006
AhR-agonist-induced transcriptional changes of genes involved in thyroid function in primary porcine thyrocytes.
Toxicological sciences : an official journal of the Society of Toxicology
Pocar P,Klonisch T,Brandsch C,Eder K,Fröhlich C,Hoang-Vu C,Hombach-Klonisch S
MA1-514 was used in western blot to investigate the effects of TCDD and dioxin-like PCB 127 on the AhR signaling pathway and on the gene expression profiles of key factors related to thyroid function
Wed Feb 01 00:00:00 EST 2006
Dioxin exerts anti-estrogenic actions in a novel dioxin-responsive telomerase-immortalized epithelial cell line of the porcine oviduct (TERT-OPEC).
Toxicological sciences : an official journal of the Society of Toxicology
Hombach-Klonisch S,Pocar P,Kauffold J,Klonisch T
MA1-514 was used in western blot to study the impact of PHAHs on oviduct epithelium treated with dioxin-type endocrine disruptors
Sat Apr 01 00:00:00 EST 2006
HES-1, a novel target gene for the aryl hydrocarbon receptor.
Molecular pharmacology
Thomsen JS,Kietz S,Ström A,Gustafsson JA
MA1-514 was used in western blot to study how HES-1 is regulated by estrogen receptor and AhR
Thu Jan 01 00:00:00 EST 2004
A new southwestern chemistry-based ELISA for detection of aryl hydrocarbon receptor transformation: application to the screening of its receptor agonists and antagonists.
Journal of immunological methods
Fukuda I,Nishiumi S,Yabushita Y,Mukai R,Kodoi R,Hashizume K,Mizuno M,Hatanaka Y,Ashida H
MA1-514 was used in ELISA to evaluate a novel ELISA strategy for the screening of aryl hydrocarbon receptor activators and inhibitors
Thu Apr 01 00:00:00 EST 2004
Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a.
The Journal of biological chemistry
Ray SS,Swanson HI
MA1-514 was used in western blot to study the mechanism of TCDD-induced immortalization of primary keratinocytes.
Fri Jun 25 00:00:00 EDT 2004
Characterization of the phosphorylation status of the hepatitis B virus X-associated protein 2.
Archives of biochemistry and biophysics
Dull AB,Carlson DB,Petrulis JR,Perdew GH
MA1-514 was used in western blot to indentify the phosphorylation status of the hepatitis B virus X-associated protein 2
Tue Oct 15 00:00:00 EDT 2002
Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization.
Biochemistry
Meyer BK,Perdew GH
MA1-514 was used in western blot to investigate the function of XAP2 for the regulation of AhR stabilization
Tue Jul 13 00:00:00 EDT 1999
Expression of the aryl hydrocarbon receptor is regulated by serum and mitogenic growth factors in murine 3T3 fibroblasts.
The Journal of biological chemistry
Vaziri C,Schneider A,Sherr DH,Faller DV
MA1-514 was used in western blot to investigate the regulation of AhR by serum and growth factors in the cell cycle
Fri Oct 18 00:00:00 EDT 1996
Subunit composition of the heteromeric cytosolic aryl hydrocarbon receptor complex.
The Journal of biological chemistry
Chen HS,Perdew GH
MA1-514 was used in western blot to identify the subunits of AhR complex
Fri Nov 04 00:00:00 EST 1994