Product References
HMCES protects immunoglobulin genes specifically from deletions during somatic hypermutation.
Genes & development
Wu L,Shukla V,Yadavalli AD,Dinesh RK,Xu D,Rao A,Schatz DG
Published figure using AID monoclonal antibody (Product # 39-2500) in Western Blot
Fri Apr 01 00:00:00 EDT 2022
Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID.
The Journal of clinical investigation
Kuhny M,Forbes LR,Çakan E,Vega-Loza A,Kostiuk V,Dinesh RK,Glauzy S,Stray-Pedersen A,Pezzi AE,Hanson IC,Vargas-Hernandez A,Xu ML,Coban-Akdemir ZH,Jhangiani SN,Muzny DM,Gibbs RA,Lupski JR,Chinn IK,Schatz DG,Orange JS,Meffre E
39-2500 was used in Western Blotting to conclude that CTNNBL1 plays an important role in regulating AID-dependent antibody diversification in humans.
Mon Aug 03 00:00:00 EDT 2020
Plasma cells, plasmablasts, and AID+/CD30+ B lymphoblasts inside and outside germinal centres: details of the basal light zone and the outer zone in human palatine tonsils.
Histochemistry and cell biology
Steiniger BS,Raimer L,Ecke A,Stuck BA,Cetin Y
39-2500 was used in Immunohistochemistry to analyse the location, phenotype, and proliferation of germinal centres plasma cells by immunohistology comparing them to plasma cells in the other two locations.
Wed Jul 01 00:00:00 EDT 2020
Optimized high-fidelity 3DPCR to assess potential mitochondrial targeting by activation-induced cytidine deaminase.
FEBS open bio
Wu H,Zhang K,Chen Y,Li J,Strout MP,Gu X
Published figure using AID monoclonal antibody (Product # 39-2500) in Western Blot
Tue Sep 01 00:00:00 EDT 2020
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes.
Cell research
Chen J,Cai Z,Bai M,Yu X,Zhang C,Cao C,Hu X,Wang L,Su R,Wang D,Wang L,Yao Y,Ye R,Hou B,Yu Y,Yu S,Li J,Xue Y
39-2500 was used in Western Blotting to identify an RNA-binding protein that is both required and sufficient to define activation-induced cytidine deaminase-binding sites genome-wide in activated B cells.
Mon Oct 01 00:00:00 EDT 2018
Regulation of the DNA Repair Complex during Somatic Hypermutation and Class-Switch Recombination.
Journal of immunology (Baltimore, Md. : 1950)
Kumar A,Priya A,Ahmed T,Grundström C,Negi N,Grundström T
39-2500 was used in Chromatin immunoprecipitation to provide early evidence for a DNA repair complex or complexes that may be of functional significance for carrying out essential roles in SH and/or CSR in B cells.
Fri Jun 15 00:00:00 EDT 2018
The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo.
Life science alliance
Maehara T,Mattoo H,Mahajan VS,Murphy SJ,Yuen GJ,Ishiguro N,Ohta M,Moriyama M,Saeki T,Yamamoto H,Yamauchi M,Daccache J,Kiyoshima T,Nakamura S,Stone JH,Pillai S
39-2500 was used in Immunohistochemistry-immunofluorescence to describe a disease-related TFH subpopulation in human tertiary lymphoid organs and SLOs that is linked to IgG4 class switching.
Mon Jan 01 00:00:00 EST 2018
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.
Nature
Compagno M,Wang Q,Pighi C,Cheong TC,Meng FL,Poggio T,Yeap LS,Karaca E,Blasco RB,Langellotto F,Ambrogio C,Voena C,Wiestner A,Kasar SN,Brown JR,Sun J,Wu CJ,Gostissa M,Alt FW,Chiarle R
Published figure using AID monoclonal antibody (Product # 39-2500) in Western Blot
Thu Feb 23 00:00:00 EST 2017
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.
Nature
Compagno M,Wang Q,Pighi C,Cheong TC,Meng FL,Poggio T,Yeap LS,Karaca E,Blasco RB,Langellotto F,Ambrogio C,Voena C,Wiestner A,Kasar SN,Brown JR,Sun J,Wu CJ,Gostissa M,Alt FW,Chiarle R
Published figure using AID monoclonal antibody (Product # 39-2500) in Western Blot
Thu Feb 23 00:00:00 EST 2017
Aberrant expression of AID and AID activators of NF-κB and PAX5 is irrelevant to EBV-associated gastric cancers, but is associated with carcinogenesis in certain EBV-non-associated gastric cancers.
Oncology letters
Mohri T,Nagata K,Kuwamoto S,Matsushita M,Sugihara H,Kato M,Horie Y,Murakami I,Hayashi K
Published figure using AID monoclonal antibody (Product # 39-2500) in Immunohistochemistry
Thu Jun 01 00:00:00 EDT 2017
Leukemic non-nodal mantle cell lymphomas have a distinct phenotype and are associated with deletion of PARP1 and 13q14.
Virchows Archiv : an international journal of pathology
Gallo M,Cacheux V,Vincent L,Bret C,Tempier A,Guittard C,Macé A,Leventoux N,Costes V,Szablewski V
392500 was used in immunohistochemistry - paraffin section to compare leukemic non-nodal mantle cell lymphoma with classical mantle cell lymphoma and aggressive mantle cell lymphoma
Thu Dec 01 00:00:00 EST 2016
Aberrant activation-induced cytidine deaminase expression in Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia.
Human pathology
Shi Y,Zhao X,Durkin L,Rogers HJ,Hsi ED
392500 was used in immunohistochemistry - paraffin section to assess the use of activation-induced cytidine deaminase staining for the detection of Philadelphia chromosome-positive acute lymphoblastic leukemia
Wed Jun 01 00:00:00 EDT 2016
Bcl6 Is Required for Somatic Hypermutation and Gene Conversion in Chicken DT40 Cells.
PloS one
Williams AM,Maman Y,Alinikula J,Schatz DG
39-2500 was used in western blot to investigate the requirement for Bcl6 for somatic hypermutation and gene conversion in chicken DT40 cells
Tue Jul 26 00:00:00 EDT 2016
Isotype-switched follicular lymphoma displays dissociation between activation-induced cytidine deaminase expression and somatic hypermutation.
Leukemia & lymphoma
Scherer F,Navarrete MA,Bertinetti-Lapatki C,Boehm J,Schmitt-Graeff A,Veelken H
39-2500 was used in immunohistochemistry to examine AID expression, the presence of SHM mutations, CSR, and aberrant SHM in BCL6 in patients with follicular lymphoma.
Thu Oct 13 00:00:00 EDT 2016
BCL2 mutations are associated with increased risk of transformation and shortened survival in follicular lymphoma.
Blood
Correia C,Schneider PA,Dai H,Dogan A,Maurer MJ,Church AK,Novak AJ,Feldman AL,Wu X,Ding H,Meng XW,Cerhan JR,Slager SL,Macon WR,Habermann TM,Karp JE,Gore SD,Kay NE,Jelinek DF,Witzig TE,Nowakowski GS,Kaufmann SH
39-2500 was used in immunohistochemistry to assess the frequency and nature of BCL2 mutations in patients with follicular lymphoma
Thu Jan 22 00:00:00 EST 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
39-2500 was used in western blot to report a B cell-intrinsic role for Rab7
Wed Apr 01 00:00:00 EDT 2015
AID expression in B-cell lymphomas causes accumulation of genomic uracil and a distinct AID mutational signature.
DNA repair
Pettersen HS,Galashevskaya A,Doseth B,Sousa MM,Sarno A,Visnes T,Aas PA,Liabakk NB,Slupphaug G,Sætrom P,Kavli B,Krokan HE
39-2500 was used in Western Blotting to demonstrate that AID-induced mutagenic U:G mismatches in DNA may be a fundamental and common cause of mutations in B-cell malignancies.
Thu Jan 01 00:00:00 EST 2015
Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factors.
Experimental cell research
Hu Y,Ericsson I,Doseth B,Liabakk NB,Krokan HE,Kavli B
39-2500 was used in immunocytochemistry and western blot to study the localization of AID and it's associated proteins
Mon Mar 10 00:00:00 EDT 2014
The role of activation-induced cytidine deaminase expression in gastric adenocarcinoma.
Anticancer research
Batsaikhan BE,Kurita N,Iwata T,Sato H,Yoshikawa K,Takasu C,Kashihara H,Matsumoto N,Ishibashi H,Shimada M
Sat Feb 01 00:00:00 EST 2014
Combinatorial H3K9acS10ph histone modification in IgH locus S regions targets 14-3-3 adaptors and AID to specify antibody class-switch DNA recombination.
Cell reports
Li G,White CA,Lam T,Pone EJ,Tran DC,Hayama KL,Zan H,Xu Z,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in ChIP assay
Thu Nov 14 00:00:00 EST 2013
Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.
PloS one
Lam T,Thomas LM,White CA,Li G,Pone EJ,Xu Z,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in Western Blot
Fri Jan 02 00:00:00 EST 2015
Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.
PloS one
Lam T,Thomas LM,White CA,Li G,Pone EJ,Xu Z,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in Western Blot
Fri Jan 02 00:00:00 EST 2015
Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.
PloS one
Lam T,Thomas LM,White CA,Li G,Pone EJ,Xu Z,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in Western Blot
Fri Jan 02 00:00:00 EST 2015
Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.
PloS one
Lam T,Thomas LM,White CA,Li G,Pone EJ,Xu Z,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in Western Blot
Fri Jan 02 00:00:00 EST 2015
Scaffold functions of 14-3-3 adaptors in B cell immunoglobulin class switch DNA recombination.
PloS one
Lam T,Thomas LM,White CA,Li G,Pone EJ,Xu Z,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in Western Blot
Fri Jan 02 00:00:00 EST 2015
Aberrant expression and mutation-inducing activity of AID in human lung cancer.
Annals of surgical oncology
Shinmura K,Igarashi H,Goto M,Tao H,Yamada H,Matsuura S,Tajima M,Matsuda T,Yamane A,Funai K,Tanahashi M,Niwa H,Ogawa H,Sugimura H
39-2500 was used in western blot to examine the expression and effect of AID on human lung cancer.
Fri Jul 01 00:00:00 EDT 2011
Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component.
PloS one
Mechtcheriakova D,Sobanov Y,Holtappels G,Bajna E,Svoboda M,Jaritz M,Bachert C,Jensen-Jarolim E
39-2500 was used in immunohistochemistry - paraffin section to study AID-related changes in chronic rhinosinusitis with nasal polyps
Mon Jan 30 00:00:00 EST 2012
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.
Nature structural & molecular biology
Xu Z,Fulop Z,Wu G,Pone EJ,Zhang J,Mai T,Thomas LM,Al-Qahtani A,White CA,Park SR,Steinacker P,Li Z,Yates J,Herron B,Otto M,Zan H,Fu H,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in ChIP assay
Wed Sep 01 00:00:00 EDT 2010
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.
Nature structural & molecular biology
Xu Z,Fulop Z,Wu G,Pone EJ,Zhang J,Mai T,Thomas LM,Al-Qahtani A,White CA,Park SR,Steinacker P,Li Z,Yates J,Herron B,Otto M,Zan H,Fu H,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in ChIP assay
Wed Sep 01 00:00:00 EDT 2010
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.
Nature structural & molecular biology
Xu Z,Fulop Z,Wu G,Pone EJ,Zhang J,Mai T,Thomas LM,Al-Qahtani A,White CA,Park SR,Steinacker P,Li Z,Yates J,Herron B,Otto M,Zan H,Fu H,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in ChIP assay
Wed Sep 01 00:00:00 EDT 2010
14-3-3 adaptor proteins recruit AID to 5'-AGCT-3'-rich switch regions for class switch recombination.
Nature structural & molecular biology
Xu Z,Fulop Z,Wu G,Pone EJ,Zhang J,Mai T,Thomas LM,Al-Qahtani A,White CA,Park SR,Steinacker P,Li Z,Yates J,Herron B,Otto M,Zan H,Fu H,Casali P
Published figure using AID monoclonal antibody (Product # 39-2500) in ChIP assay
Wed Sep 01 00:00:00 EDT 2010
E2A-positive gastric MALT lymphoma has weaker plasmacytoid infiltrates and stronger expression of the memory B-cell-associated miR-223: possible correlation with stage and treatment response.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Liu TY,Chen SU,Kuo SH,Cheng AL,Lin CW
Mon Nov 01 00:00:00 EDT 2010
Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells.
Journal of immunology (Baltimore, Md. : 1950)
Misaghi S,Garris CS,Sun Y,Nguyen A,Zhang J,Sebrell A,Senger K,Yan D,Lorenzo MN,Heldens S,Lee WP,Xu M,Wu J,DeForge L,Sai T,Dixit VM,Zarrin AA
Thu Jul 01 00:00:00 EDT 2010
