Product References
Effects of the Rho GTPase-activating toxin CNF1 on fibroblasts derived from Rett syndrome patients: A pilot study.
Journal of cellular and molecular medicine
Cittadini C,Germinario EAP,Maroccia Z,Cosentino L,Maselli V,Gambardella L,Giambenedetti M,Guidotti M,Travaglione S,Fallerini C,Renieri A,Marcillo DIE,Ricceri L,Fortini P,De Filippis B,Fiorentini C,Fabbri A
44-609G was used in Western Blotting to find that CNF1 treatment modulates the Rho GTPases activity of RTT fibroblasts and induces a considerable re-organization of the actin cytoskeleton, mainly in stress fibres.
Mon May 01 00:00:00 EDT 2023
Effects of the Rho GTPase-activating toxin CNF1 on fibroblasts derived from Rett syndrome patients: A pilot study.
Journal of cellular and molecular medicine
Cittadini C,Germinario EAP,Maroccia Z,Cosentino L,Maselli V,Gambardella L,Giambenedetti M,Guidotti M,Travaglione S,Fallerini C,Renieri A,Marcillo DIE,Ricceri L,Fortini P,De Filippis B,Fiorentini C,Fabbri A
44-609G was used in Western Blotting to find that CNF1 treatment modulates the Rho GTPases activity of RTT fibroblasts and induces a considerable re-organization of the actin cytoskeleton, mainly in stress fibres.
Mon May 01 00:00:00 EDT 2023
Protective Effect of Fucoxanthin on Zearalenone-Induced Hepatic Damage through Nrf2 Mediated by PI3K/AKT Signaling.
Marine drugs
Ben Ammar R,Zahra HA,Abu Zahra AM,Alfwuaires M,Abdulaziz Alamer S,Metwally AM,Althnaian TA,Al-Ramadan SY
Published figure using AKT Pan polyclonal antibody (Product # 44-609G) in Western Blot
Mon Jul 03 00:00:00 EDT 2023
Dihydro-Resveratrol Attenuates Oxidative Stress, Adipogenesis and Insulin Resistance in In Vitro Models and High-Fat Diet-Induced Mouse Model via AMPK Activation.
Nutrients
Lam CS,Xia YX,Chen BS,Du YX,Liu KL,Zhang HJ
44-609G was used in Western Blotting to examine the in vitro and in vivo effects of dihydro-resveratrol (DR2), a naturally occurring compound from Dendrobium medicinal plants, on oxidative stress aggravation, adipogenesis, lipogenesis and insulin sensitivity.
Fri Jun 30 00:00:00 EDT 2023
Dihydro-Resveratrol Attenuates Oxidative Stress, Adipogenesis and Insulin Resistance in In Vitro Models and High-Fat Diet-Induced Mouse Model via AMPK Activation.
Nutrients
Lam CS,Xia YX,Chen BS,Du YX,Liu KL,Zhang HJ
44-609G was used in Western Blotting to examine the in vitro and in vivo effects of dihydro-resveratrol (DR2), a naturally occurring compound from Dendrobium medicinal plants, on oxidative stress aggravation, adipogenesis, lipogenesis and insulin sensitivity.
Fri Jun 30 00:00:00 EDT 2023
PTPN14 promotes gastric cancer progression by PI3KA/AKT/mTOR pathway.
Cell death & disease
Li H,Guan B,Liu S,Liu H,Song L,Zhang G,Zhao R,Zhou C,Gao P
44-609G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to provide a theoretical basis to better understand the occurrence and development of gastric cancer.
Fri Mar 10 00:00:00 EST 2023
Calystegines Improve the Metabolic Activity of Human Adipose Derived Stromal Stem Cells (ASCs) under Hyperglycaemic Condition through the Reduction of Oxidative/ER Stress, Inflammation, and the Promotion of the AKT/PI3K/mTOR Pathway.
Biomolecules
Kowalczuk A,Bourebaba N,Panchuk J,Marycz K,Bourebaba L
44-609G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to study the effect of calystegines in an experimental model of hyperglycaemia induced on human ASCs cells.
Wed Mar 16 00:00:00 EDT 2022
Calystegines Improve the Metabolic Activity of Human Adipose Derived Stromal Stem Cells (ASCs) under Hyperglycaemic Condition through the Reduction of Oxidative/ER Stress, Inflammation, and the Promotion of the AKT/PI3K/mTOR Pathway.
Biomolecules
Kowalczuk A,Bourebaba N,Panchuk J,Marycz K,Bourebaba L
44-609G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to study the effect of calystegines in an experimental model of hyperglycaemia induced on human ASCs cells.
Wed Mar 16 00:00:00 EDT 2022
Pre-Exposure to Stress-Inducing Agents Increase the Anticancer Efficacy of Focused Ultrasound against Aggressive Prostate Cancer Cells.
Antioxidants (Basel, Switzerland)
Murad HY,Chandra PK,Kelly CA,Khurana N,Yu H,Bortz EP,Hong SN,Mondal D,Khismatullin DB
Published figure using AKT Pan polyclonal antibody (Product # 44-609G) in Western Blot
Wed Feb 09 00:00:00 EST 2022
LINC00960 regulates cell proliferation and glycolysis in pancreatic cancer through the miR-326-3p/TUFT1/AKT-mTOR axis.
The Kaohsiung journal of medical sciences
Zhou B,Lei JH,Wang Q,Qu TF,Cha LC,Zhan HX,Liu SL,Hu X,Sun CD,Cao JY,Qiu FB,Guo WD
Published figure using AKT Pan polyclonal antibody (Product # 44-609G) in Western Blot
Thu Dec 01 00:00:00 EST 2022
LncRNA FOXD3-AS1 aggravates myocardial ischemia/reperfusion injury by inactivating the Redd1/AKT/GSK3β/Nrf2 signaling pathway via the miR-128/TXNIP axis.
Journal of biochemical and molecular toxicology
Chen B,Zheng L,Zhu T,Jiao K
44-609G was used in Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that both inhibition of miR-128 and overexpression of TXNIP reversed the cardioprotective effect of FOXD3-AS1 small interfering RNA in H/R-induced H9c2 cells.
Thu Dec 01 00:00:00 EST 2022
MicroRNA‑203a‑3p suppresses endothelial cell proliferation and invasion, and promotes apoptosis in hemangioma by inactivating the VEGF‑mediated PI3K/AKT pathway.
Experimental and therapeutic medicine
Hu Z,Zhuo L,Li Y,Duan D,Guo J
44-609G was used in Western Blotting to further investigate the effects of miR-203a-3p on endothelial cell proliferation, invasion and apoptosis, as well as its underlying mechanism in hemangioma.
Tue Nov 01 00:00:00 EDT 2022
Low-Dose Albendazole Inhibits Epithelial-Mesenchymal Transition of Melanoma Cells by Enhancing Phosphorylated GSK-3β/Tyr216 Accumulation.
Journal of oncology
He Z,Lei S,Liang F,Tan L,Zhang W,Xie L,Zheng H,Lu Y
Published figure using AKT Pan polyclonal antibody (Product # 44-609G) in Western Blot
Fri Dec 31 00:00:00 EST 2021
Cardiac Protective Effect of Kirenol against Doxorubicin-Induced Cardiac Hypertrophy in H9c2 Cells through Nrf2 Signaling via PI3K/AKT Pathways.
International journal of molecular sciences
Alzahrani AM,Rajendran P,Veeraraghavan VP,Hanieh H
Published figure using AKT Pan polyclonal antibody (Product # 44-609G) in Western Blot
Tue Mar 23 00:00:00 EDT 2021
Hyoscyamus albus nortropane alkaloids reduce hyperglycemia and hyperinsulinemia induced in HepG2 cells through the regulation of SIRT1/NF-kB/JNK pathway.
Cell communication and signaling : CCS
Kowalczuk A,Bourebaba N,Kornicka-Garbowska K,Turlej E,Marycz K,Bourebaba L
44-609G was used in Western Blot to demonstrate that calystegines from Hyoscyamus albus provide cytoprotection to the HepG2 cells against insulin/glucose induced insulin resistance and apoptosis due to the regulation of SIRT1/Foxo1/G6PC/mTOR and NF-κB/JNK/TLR4 signaling pathways.
Tue May 25 00:00:00 EDT 2021
Hyoscyamus albus nortropane alkaloids reduce hyperglycemia and hyperinsulinemia induced in HepG2 cells through the regulation of SIRT1/NF-kB/JNK pathway.
Cell communication and signaling : CCS
Kowalczuk A,Bourebaba N,Kornicka-Garbowska K,Turlej E,Marycz K,Bourebaba L
44-609G was used in Western Blot to demonstrate that calystegines from Hyoscyamus albus provide cytoprotection to the HepG2 cells against insulin/glucose induced insulin resistance and apoptosis due to the regulation of SIRT1/Foxo1/G6PC/mTOR and NF-κB/JNK/TLR4 signaling pathways.
Tue May 25 00:00:00 EDT 2021
Effect and mechanism of downregulating the long-chain noncoding RNA TM4SF1-AS1 on the proliferation, apoptosis and invasion of gastric cancer cells.
World journal of surgical oncology
He C,Qi W,Wang Z
44-609G was used in Western Blot to investigate long-chain noncoding TM4SF1-AS1 in gastric cancer (GC) tissues and cells.
Sat Jul 31 00:00:00 EDT 2021
Effect and mechanism of downregulating the long-chain noncoding RNA TM4SF1-AS1 on the proliferation, apoptosis and invasion of gastric cancer cells.
World journal of surgical oncology
He C,Qi W,Wang Z
44-609G was used in Western Blot to investigate long-chain noncoding TM4SF1-AS1 in gastric cancer (GC) tissues and cells.
Sat Jul 31 00:00:00 EDT 2021
Phosphorylation site S122 in estrogen receptor α has a tissue-dependent role in female mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ohlsson C,Gustafsson KL,Farman HH,Henning P,Lionikaite V,Movérare-Skrtic S,Sjögren K,Törnqvist AE,Andersson A,Islander U,Bernardi AI,Poutanen M,Chambon P,Lagerquist MK
44-609G was used in Western Blot to demonstrate in vivo that a phosphorylation site in a transactivation domain in a nuclear steroid receptor modulates the receptor activity in a tissue-dependent manner.
Tue Dec 01 00:00:00 EST 2020
Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK‑3β/β‑catenin signaling pathway by downregulating miR‑25‑3p.
International journal of molecular medicine
Cao Y,Lv W,Ding W,Li J
Published figure using AKT Pan polyclonal antibody (Product # 44-609G) in Western Blot
Wed Jul 01 00:00:00 EDT 2020
Sevoflurane inhibits the proliferation and invasion of hepatocellular carcinoma cells through regulating the PTEN/Akt/GSK‑3β/β‑catenin signaling pathway by downregulating miR‑25‑3p.
International journal of molecular medicine
Cao Y,Lv W,Ding W,Li J
Published figure using AKT Pan polyclonal antibody (Product # 44-609G) in Western Blot
Wed Jul 01 00:00:00 EDT 2020
A-kinase-interacting protein 1 promotes EMT and metastasis via PI3K/Akt/IKKβ pathway in cervical cancer.
Cell biochemistry and function
Zhang X,Liu S,Zhu Y
44-609G was used in Western Blotting to investigate the clinical potential of AKIP1 during cervical cancer using BrdU and wound healing experiments.
Sat Aug 01 00:00:00 EDT 2020
A-kinase-interacting protein 1 promotes EMT and metastasis via PI3K/Akt/IKKβ pathway in cervical cancer.
Cell biochemistry and function
Zhang X,Liu S,Zhu Y
44-609G was used in Western Blotting to investigate the clinical potential of AKIP1 during cervical cancer using BrdU and wound healing experiments.
Sat Aug 01 00:00:00 EDT 2020
Wild‑type IDH1 affects cell migration by modulating the PI3K/AKT/mTOR pathway in primary glioblastoma cells.
Molecular medicine reports
Shen X,Wu S,Zhang J,Li M,Xu F,Wang A,Lei Y,Zhu G
44-609G was used in Western Blotting to explore the mechanisms governing IDH1's control of glioblastoma cell migration.
Tue Sep 01 00:00:00 EDT 2020
Wild‑type IDH1 affects cell migration by modulating the PI3K/AKT/mTOR pathway in primary glioblastoma cells.
Molecular medicine reports
Shen X,Wu S,Zhang J,Li M,Xu F,Wang A,Lei Y,Zhu G
44-609G was used in Western Blotting to explore the mechanisms governing IDH1's control of glioblastoma cell migration.
Tue Sep 01 00:00:00 EDT 2020
Inhibitory Activity of Boesenbergia rotunda (L.) Mansf. Rhizome towards the Expression of Akt and NF-KappaB p65 in Acetic Acid-Induced Wistar Rats.
Evidence-based complementary and alternative medicine : eCAM
Rosdianto AM,Puspitasari IM,Lesmana R,Levita J
44-609G was used in Western Blot to conclude that BREE could inhibit the expression of Akt and NF-kappaB p65 in the stomach and intestine of acetic acid-induced Wistar rats.
Fri Apr 15 00:00:00 EDT 2022
Kaempferol Inhibits Zearalenone-Induced Oxidative Stress and Apoptosis via the PI3K/Akt-Mediated Nrf2 Signaling Pathway: In Vitro and In Vivo Studies.
International journal of molecular sciences
Rajendran P,Ammar RB,Al-Saeedi FJ,Mohamed ME,ElNaggar MA,Al-Ramadan SY,Bekhet GM,Soliman AM
44-609G was used in Western Blotting to demonstrate that kaempferol possesses notable hepatoprotective roles against zearalenone-induced damage, potentially through the stimulation of Nrf2/HO-1 cascades and PI3K/Akt signalling.
Mon Dec 28 00:00:00 EST 2020
Kaempferol Inhibits Zearalenone-Induced Oxidative Stress and Apoptosis via the PI3K/Akt-Mediated Nrf2 Signaling Pathway: In Vitro and In Vivo Studies.
International journal of molecular sciences
Rajendran P,Ammar RB,Al-Saeedi FJ,Mohamed ME,ElNaggar MA,Al-Ramadan SY,Bekhet GM,Soliman AM
44-609G was used in Western Blotting to demonstrate that kaempferol possesses notable hepatoprotective roles against zearalenone-induced damage, potentially through the stimulation of Nrf2/HO-1 cascades and PI3K/Akt signalling.
Mon Dec 28 00:00:00 EST 2020
Fat-Specific Protein 27 Regulation of Vascular Function in Human Obesity.
Journal of the American Heart Association
Karki S,Farb MG,Sharma VM,Jash S,Zizza EJ,Hess DT,Carmine B,Carter CO,Pernar LI,Apovian CM,Puri V,Gokce N
44-609G was used in Western Blotting to support a key role and functional significance of FSP27 as a critical endogenous modulator of human microvascular function that has not been previously described.
Tue Jun 04 00:00:00 EDT 2019
Fat-Specific Protein 27 Regulation of Vascular Function in Human Obesity.
Journal of the American Heart Association
Karki S,Farb MG,Sharma VM,Jash S,Zizza EJ,Hess DT,Carmine B,Carter CO,Pernar LI,Apovian CM,Puri V,Gokce N
44-609G was used in Western Blotting to support a key role and functional significance of FSP27 as a critical endogenous modulator of human microvascular function that has not been previously described.
Tue Jun 04 00:00:00 EDT 2019
Preconception paternal alcohol exposure exerts sex-specific effects on offspring growth and long-term metabolic programming.
Epigenetics & chromatin
Chang RC,Wang H,Bedi Y,Golding MC
44-609G was used in Western Blotting to investigate the long-term impact of chronic preconception paternal alcohol use on offspring growth and metabolic programming.
Tue Jan 22 00:00:00 EST 2019
Programmed increases in LXRα induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity.
Molecular metabolism
Chang RC,Thomas KN,Bedi YS,Golding MC
44-609G was used in Western Blotting to study LXR-alpha in metabolic changes in children due to prenatal paternal alcohol consumption.
Sun Dec 01 00:00:00 EST 2019
Sixty years old is the breakpoint of human frontal cortex aging.
Free radical biology & medicine
Cabré R,Naudí A,Dominguez-Gonzalez M,Ayala V,Jové M,Mota-Martorell N,Piñol-Ripoll G,Gil-Villar MP,Rué M,Portero-Otín M,Ferrer I,Pamplona R
44609G was used in immunohistochemistry - paraffin section and western blot to discover that protein oxidative and glycoxidative damage significantly increases during human brain aging
Wed Feb 01 00:00:00 EST 2017
A rich medium-chain triacylglycerol diet benefits adiposity but has adverse effects on the markers of hepatic lipogenesis and beta-oxidation.
Food & function
Chamma CM,Bargut TC,Mandarim-de-Lacerda CA,Aguila MB
44-609G was used in western blot to describe the effects of dietary medium-chain triacylglycerols on hepatic lipid metabolism
Wed Feb 22 00:00:00 EST 2017
Differential effects of angiotensin receptor blockers on pancreatic islet remodelling and glucose homeostasis in diet-induced obese mice.
Molecular and cellular endocrinology
Graus-Nunes F,Marinho TS,Barbosa-da-Silva S,Aguila MB,Mandarim-de-Lacerda CA,Souza-Mello V
44609G was used in western blot to compare the effects of losartan and telmisartan on pancreatic islets remodeling and glucose homeostasis in diet-induced obese mice
Thu Jan 05 00:00:00 EST 2017
Thermogenesis, fatty acid synthesis with oxidation, and inflammation in the brown adipose tissue of ob/ob (-/-) mice.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
Martins FF,Bargut TCL,Aguila MB,Mandarim-de-Lacerda CA
44609G was used in western blot to find that the lack of substrate for thermogenesis and the local inflammation negatively regulated thermogenic signaling in the ob/ob mice
Wed Mar 01 00:00:00 EST 2017
Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner.
Oncotarget
Tam KJ,Dalal K,Hsing M,Cheng CW,Khosravi S,Yenki P,Tse C,Peacock JW,Sharma A,Chiang YT,Wang Y,Cherkasov A,Rennie PS,Gleave ME,Ong CJ
44609G was used in western blot to define and study the androgen response element within the SEMA3C locus
Tue Feb 07 00:00:00 EST 2017
Pooled screening for antiproliferative inhibitors of protein-protein interactions.
Nature chemical biology
Nim S,Jeon J,Corbi-Verge C,Seo MH,Ivarsson Y,Moffat J,Tarasova N,Kim PM
44-609G was used in western blot to assess antiproliferative inhibitors of protein-protein interactions by pooled screening
Fri Apr 01 00:00:00 EDT 2016
Adverse effects of vitamin D deficiency on the Pi3k/Akt pathway and pancreatic islet morphology in diet-induced obese mice.
Molecular nutrition & food research
Borges CC,Salles AF,Bringhenti I,Souza-Mello V,Mandarim-de-Lacerda CA,Aguila MB
44-609G was used in western blot to examine the impact of vitamin D deficiency on insulin resistance and abnormal glucose homeostasis in obesity.
Mon Feb 01 00:00:00 EST 2016
A high-fish-oil diet prevents adiposity and modulates white adipose tissue inflammation pathways in mice.
The Journal of nutritional biochemistry
Bargut TC,Mandarim-de-Lacerda CA,Aguila MB
44-609G was used in western blot to study the regulatory effect of a high-fish-oil diet on rodent white adipose tissue inflammation pathways
Tue Sep 01 00:00:00 EDT 2015
p53 attenuates AKT signaling by modulating membrane phospholipid composition.
Oncotarget
Rueda-Rincon N,Bloch K,Derua R,Vyas R,Harms A,Hankemeier T,Khan NA,Dehairs J,Bagadi M,Binda MM,Waelkens E,Marine JC,Swinnen JV
44-609G was used in western blot to report a role for p53 in regulating the membrane phospholipids composition.
Fri Aug 28 00:00:00 EDT 2015
Effect of whole-body vibration and insulin-like growth factor-I on muscle paralysis-induced bone degeneration after botulinum toxin injection in mice.
Calcified tissue international
Niehoff A,Lechner P,Ratiu O,Reuter S,Hamann N,Brüggemann GP,Schönau E,Bloch W,Beccard R
44-609G was used in immunohistochemistry to test if whole-body vibration and insulin-like growth factor-I treatment counteract paralysis-induced bone degradation following botulinum toxin A injections via protein kinase B signaling.
Tue Apr 01 00:00:00 EDT 2014
GPR30 activation is neither necessary nor sufficient for acute neuroprotection by 17β-estradiol after an ischemic injury in organotypic hippocampal slice cultures.
Brain research
Lamprecht MR,Morrison B
44-609G was used in western blot to examine the role of GPR30 in 7β-estradiol-mediated neuroprotection after an ischemic injury in an organotypic hippocampal slice culture model.
Wed May 14 00:00:00 EDT 2014
Enhanced pan-peroxisome proliferator-activated receptor gene and protein expression in adipose tissue of diet-induced obese mice treated with telmisartan.
Experimental physiology
Penna-de-Carvalho A,Graus-Nunes F,Rabelo-Andrade J,Mandarim-de-Lacerda CA,Souza-Mello V
Published figure using AKT Pan polyclonal antibody (Product # 44-609G) in Western Blot
Mon Dec 01 00:00:00 EST 2014
Signaling in sperm: toward a molecular understanding of the acquisition of sperm motility in the mouse epididymis.
Biology of reproduction
Vadnais ML,Aghajanian HK,Lin A,Gerton GL
Fri Nov 01 00:00:00 EDT 2013