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FIGURE: 1 / 1
Positive Samples: SH-SY5Y, 293T; Cellular Location: Cytoplasm, Membrane, Nucleus, Peripheral membrane protein
Immunogen sequence: DTPEEREEWT EAIQAVADRL QRQEEERMNC SPTSQIDNIG EEEMDASTTH HKRKTMNDFD YLKLLGKGTF GKVILVREKA SGKYYAMKIL KKEVIIAKDE V
AKT3 (PKB gamma) has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). It is involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, glycogen synthesis and glucose uptake. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described.
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Protein Aliases: AKT3 kinase; DKFZP434N0250; PKB gamma; Protein kinase Akt-3; Protein kinase B gamma; protein kinase B, gamma; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-gamma; STK-2; thymoma viral proto-oncogene 3; v-akt murine thymoma viral oncogene 3; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
Gene Aliases: AI851531; AKT3; D930002M15Rik; MPPH; MPPH2; Nmf350; PKB-GAMMA; PKBG; PRKBG; RAC-gamma; RAC-PK-gamma; STK-2
UniProt ID: (Human) Q9Y243, (Rat) Q63484, (Mouse) Q9WUA6
Entrez Gene ID: (Human) 10000, (Rat) 29414, (Mouse) 23797
Molecular Function: non-receptor serine/threonine protein kinase
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