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Product Details
ALDH1-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 441-491 on rat retinal dehydrogenase 1 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
ALDH1A1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-deoxyglucosone dehydrogenase; alcohol dehydrogenase family 1, subfamily A1; alcohol dehydrogenase family 1, subfamily A2; Aldehyde dehydrogenase 1 soluble; aldehyde dehydrogenase 1, liver cytosolic (class 1); aldehyde dehydrogenase 1, subfamily A1; Aldehyde dehydrogenase 1A1; aldehyde dehydrogenase 2; Aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase family 1, member A1; aldehyde dehydrogenase family 1, subfamily A1; Aldehyde dehydrogenase, cytosolic; ALDH-E1; ALHDII; epididymis secretory sperm binding protein Li53e; MGC2318; RALDH 1; ralDH1; Retinal dehydrogenase 1
Gene Aliases: Ahd-2; Ahd2; Aldh; Aldh1; Aldh1a1; Aldh1a2; Aldh2; E1; Raldh1
UniProt ID: (Mouse) P24549, (Rat) P51647
Entrez Gene ID: (Mouse) 11668, (Rat) 24188
retinal dehydrogenase activity
3-chloroallyl aldehyde dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
benzaldehyde dehydrogenase (NAD+) activity
identical protein binding
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
optic cup morphogenesis involved in camera-type eye development
retinoic acid biosynthetic process
response to oxidative stress
metabolic process
response to drug
retinol metabolic process
retinoic acid metabolic process
9-cis-retinoic acid biosynthetic process
9-cis-retinoic acid metabolic process
positive regulation of apoptotic process
response to ethanol
embryonic eye morphogenesis
protein homotetramerization
oxidation-reduction process
kidney development
liver development
midgut development
response to organic cyclic compound
response to estradiol
response to retinoic acid
estrous cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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