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Invitrogen
ALDH1L1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 3
ALDH1L1 Antibody (720169) in WB
Western blot was performed using Anti-ALDH1L1 Polyclonal Antibody (Product # 720169) and a 90 kDa band corresponding to ALDH1L1 was observed across the panel tested except mouse brain, mouse heart and rat heart which are reported to be negative. Tissue extracts (30 µg lysate) of Mouse Kidney (Lane 1), Mouse Liver (Lane 2), Mouse Ovary (Lane 3), Mouse Brain (Lane 4), Mouse Heart (Lane 5), Rat Kidney (Lane 6), Rat Liver (Lane 7) and Rat Heart (Lane 8) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolv... View More
Product Details
720169
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Protein corresponding to Human ALDH1L1 (aa 1-307)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 0.1% BSA, 30% glycerol
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610008
Product Specific Information
These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.
This antibody is predicted to react with Monkey and Rat.
Target Information
ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; 10fTHF; 10FTHFDH; aldehyde dehydrogenase 1 family, member L1; Aldehyde dehydrogenase family 1 member L1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; formyltetrahydrofolate dehydrogenase; MER57B-ALDH1L1
Gene Aliases: 10-fTHF; 10-FTHFDH; 1810048F20Rik; ALDH1L1; FDH; FTHFD; Neut2
UniProt ID: (Human) O75891, (Mouse) Q8R0Y6
Entrez Gene ID: (Human) 10840, (Mouse) 107747
catalytic activity
aldehyde dehydrogenase (NAD) activity
formyltetrahydrofolate dehydrogenase activity
hydroxymethyl-, formyl- and related transferase activity
aminobutyraldehyde dehydrogenase activity
4-trimethylammoniobutyraldehyde dehydrogenase activity
aldehyde dehydrogenase [NAD(P)+] activity
protein binding
methyltransferase activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
protein complex binding
aldehyde dehydrogenase (NADP+) activity
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
RNA processing factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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