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ALDH1L1 Antibody (711603) in WB
Western Blot was performed using Anti-ALDH1L1 Antibody (19HCLC), ABfinity Rabbit Oligoclonal (Product # 711603) and a 100 kDa band corresponding to ALDH1L1 was observed across the cell lines and tissues tested. Whole cell extracts (30 µg lysate) of RT-4 (Lane 1), Mouse Kidney (Lane 2), Mouse Liver (Lane 3) and Rat Liver (Lane 4) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0321BOX). Resolved proteins were then transferred onto a Nitrocellulose membrane (Product # LC2001) by iBlot® 2 Dry Blotting System (Produc... View More
Product Details
711603
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Superclonal
Type
Antibody
Clone
19HCLC
Immunogen
Protein corresponding to Human ALDH1L1 (aa 1-307)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2633191
Product Specific Information
This antibody is predicted to react with Monkey, Rat, Cat and Mouse
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
Target Information
ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; 10fTHF; 10FTHFDH; aldehyde dehydrogenase 1 family, member L1; Aldehyde dehydrogenase family 1 member L1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; FBP-CI; formyltetrahydrofolate dehydrogenase; MER57B-ALDH1L1
Gene Aliases: 10-fTHF; 10-FTHFDH; 1810048F20Rik; ALDH1L1; FDH; FTHFD; Neut2
UniProt ID: (Human) O75891, (Rat) P28037, (Mouse) Q8R0Y6
Entrez Gene ID: (Human) 10840, (Rat) 64392, (Mouse) 107747
catalytic activity
aldehyde dehydrogenase (NAD) activity
formyltetrahydrofolate dehydrogenase activity
hydroxymethyl-, formyl- and related transferase activity
aminobutyraldehyde dehydrogenase activity
4-trimethylammoniobutyraldehyde dehydrogenase activity
aldehyde dehydrogenase [NAD(P)+] activity
methyltransferase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
protein complex binding
aldehyde dehydrogenase (NADP+) activity
protein binding
oxidoreductase activity
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
RNA processing factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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