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Product Details
PA5-112582
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human 5'-AMP-activated protein kinase subunit gamma-1 protein (1-331AA)
Conjugate
Form
Liquid
Concentration
6 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2867317
Target Information
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase, gamma-1 subunit; AMP-activated protein kinase, noncatalytic gamma-1 subunit; ampk gamma; AMPK gamma-1 chain; AMPK gamma1; AMPK subunit gamma-1; AMPKg; Protein kinase AMP-activated gamma; protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Gene Aliases: AMPKG; Prkaac; PRKAG1; Prkga1
UniProt ID: (Human) P54619, (Rat) P80385
Entrez Gene ID: (Human) 5571, (Rat) 25520
regulation of glycolytic process
protein phosphorylation
fatty acid biosynthetic process
cell cycle arrest
signal transduction
spermatogenesis
positive regulation of gene expression
macroautophagy
positive regulation of protein kinase activity
regulation of signal transduction by p53 class mediator
regulation of catalytic activity
protein heterooligomerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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