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ANP (Atrial Natriuretic peptide)/BNP Antibody (601-700) in WB
Western Blot: The 134 aa of human BNP recombinant protein was resolved onto 12% SDS-PAGE, transferred onto NC membrane, and immunoblotted by Rabbit anti –ANP antibody (Cat#601-700) at 1:500. An immunoreactive band around ~18 kDa was observed.
Product Details
601-700
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 10 aa synthetic peptide derived from C-terminus human ANP/BNP protein
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with proprietary stabilizer
Contains
0.01% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Positive control: Recombinant BNP protein
Cellular location: Cytoplasmic, secreted.
Target Information
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Atrial natriuretic factor prohormone; Atrial natriuretic peptide prohormone; Atriopeptigen; atriopeptin; Cardiodilatin; cardiodilatin-related peptide; cardionatrin; CDD; natriuretic peptide precursor A variant 1; Natriuretic peptides A; preproANP; preproCDD-ANF; prepronatriodilatin; proANF; Pronatriodilatin; urodilatin
Gene Aliases: ANF; ANP; ATFB6; ATRST2; CDD; CDD-ANF; CDP; NPPA; PND
UniProt ID: (Human) P01160
Entrez Gene ID: (Human) 4878
response to hypoxia
negative regulation of systemic arterial blood pressure
cGMP biosynthetic process
transcription initiation from RNA polymerase II promoter
receptor guanylyl cyclase signaling pathway
neuropeptide signaling pathway
female pregnancy
regulation of blood pressure
positive regulation of heart rate
cardiac muscle hypertrophy in response to stress
negative regulation of cell growth
response to insulin
response to muscle stretch
cellular protein metabolic process
regulation of blood vessel size
regulation of atrial cardiac muscle cell membrane repolarization
positive regulation of cardiac muscle contraction
cell growth involved in cardiac muscle cell development
cellular response to mechanical stimulus
regulation of high voltage-gated calcium channel activity
positive regulation of delayed rectifier potassium channel activity
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
positive regulation of potassium ion export across plasma membrane
regulation of cardiac conduction
negative regulation of collecting lymphatic vessel constriction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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