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APITD1 Antibody (PA5-104352) in IHC (P)
Immunohistochemistry analysis of APITD1 in rat colorectal tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with APITD1 polyclonal antibody (Product # PA5-104352) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-104352
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CENPS(Accession Q8N2Z9), corresponding to amino acid residues K99-N138.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853662
Product Specific Information
Antibody detects endogenous levels of total CENPS.
Target Information
APITD1 was identified in the neuroblastoma tumour suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF(II)31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumours, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptosis-inducing TAF9-like domain-containing protein 1; Apoptosis-inducing TAF9-like domain-containing protein 1 homolog; CENP-S; Centromere protein S; FANCM-associated histone fold protein 1; FANCM-interacting histone fold protein 1; Fanconi anemia-associated polypeptide of 16 kDa; ortholog of human apoptosis-inducing, TAF9-like domain 1 APITD1
Gene Aliases: 2610040C18Rik; 2810407L01Rik; APITD1; CENP-S; CENPS; FAAP16; MHF1
UniProt ID: (Human) Q8N2Z9, (Mouse) Q9D084
Entrez Gene ID: (Human) 378708, (Mouse) 69928, (Rat) 100534597
resolution of meiotic recombination intermediates
DNA repair
mitotic recombination
cellular response to DNA damage stimulus
sister chromatid cohesion
mitotic nuclear division
replication fork processing
positive regulation of protein ubiquitination
CENP-A containing nucleosome assembly
interstrand cross-link repair
cell division
kinetochore assembly
cell cycle
pentose-phosphate shunt
oxidation-reduction process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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