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Product Details
H00008862-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2A1-2D5
Immunogen
APLN (AAH21104.1, 1 a.a. approximately 122 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.48 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MSATWCSPEG QGMGQGPGRE VGGNSAASGP ASPIRDPCLS EAGLKGPPSA HPRRLCLLHR LVCFSGGLTS IQLSPRTCCS HQWAQLFSPA CFPQWRAPGC SLDDSRSLTR IRPVHLPGPS LD
Target Information
This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AGTRL1 ligand; Apelin; APJ endogenous ligand
Gene Aliases: APEL; APLN; XNPEP2
UniProt ID: (Human) Q9ULZ1
Entrez Gene ID: (Human) 8862
regulation of the force of heart contraction
immune response
signal transduction
lactation
positive regulation of cell proliferation
positive regulation of heat generation
positive regulation of phosphorylation
drinking behavior
regulation of respiratory gaseous exchange
negative regulation of blood pressure
negative regulation of vasoconstriction
positive regulation of vasodilation
positive regulation of corticotropin secretion
positive regulation of corticotropin-releasing hormone secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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