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Product Details
14559-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
APOBEC3B Fusion Protein Ag6115 (1-251 aa encoded by BC053859)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MNPQIRNPM ERMYRDTFYD NFENEPILYG RSYTWLCYEV KIKRGRSNLL WDTGVFRGQV YFEPQYHAEM CFLSWFCGNQ LPAYKCFQIT WFVSWTPCPD CVAKLAEFLS EHPNVTLTIS AARLYYYWER DYRRALCRLS QAGARVKIMD YEEFAYCWEN FVYNEGQQFM PWYKFDENYA FLHRTLKEIL RLRIFSVAFT AAMRSCASWT WFLLCSWTRP RSTGSLGSSP GAPASPGAVP GKCVRSFRRT HT (1-251 aa encoded by BC053859)
Target Information
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A3B; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3B; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B; bK150C 2.2; cytidine deaminase; DNA dC->dU-editing enzyme APOBEC-3B; FLJ21201; phorbolin 2; phorbolin 3; Phorbolin-1-related protein; Phorbolin-2/3; probable DNA dC->dU-editing enzyme APOBEC-3B
Gene Aliases: A3B; APOBEC1L; APOBEC3B; ARCD3; ARP4; bK150C2.2; DJ742C19.2; PHRBNL
UniProt ID: (Human) Q9UH17
Entrez Gene ID: (Human) 9582
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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