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Product Details
BS-12131R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human APXL, amino acids 701-850.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apical-like protein; APX homolog of Xenopus; liver regeneration-related protein LRRG167; Protein APXL; Protein Shroom2
Gene Aliases: 4832440C16; Ab2-404; APXL; C630003H05Rik; HSAPXL; Shrm2; SHROOM2
UniProt ID: (Human) Q13796, (Mouse) A2ALU4
Entrez Gene ID: (Human) 357, (Mouse) 110380, (Rat) 317435
cell morphogenesis
lens morphogenesis in camera-type eye
brain development
eye pigment granule organization
cell migration
establishment of melanosome localization
melanosome organization
sodium ion transmembrane transport
camera-type eye development
cellular pigment accumulation
ear development
apical protein localization
camera-type eye morphogenesis
actin filament bundle assembly
multicellular organism development
negative regulation of actin filament depolymerization
cell-cell junction maintenance
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