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Product Details
ARF4-401AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to unique amino acid sequence on ARF4 protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
ADP-ribosylation factor 1 is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I and class III, and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosylation factor 2; ADP-ribosylation factor 4
Gene Aliases: AA407803; ARF2; ARF4
UniProt ID: (Human) P18085, (Rat) P61751, (Mouse) P61750
Entrez Gene ID: (Human) 378, (Rat) 79120, (Mouse) 11843
protein ADP-ribosylation
ER to Golgi vesicle-mediated transport
retrograde vesicle-mediated transport, Golgi to ER
epidermal growth factor receptor signaling pathway
small GTPase mediated signal transduction
brain development
learning
protein transport
cell migration
activation of phospholipase D activity
negative regulation of apoptotic process
positive regulation of GTPase activity
apical protein localization
establishment or maintenance of epithelial cell apical/basal polarity
positive regulation of transcription from RNA polymerase II promoter
response to axon injury
dendritic spine development
protein localization to cilium
regulation of reactive oxygen species metabolic process
vesicle-mediated transport
transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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