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For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to rat collybistin protein. Alternative splicing of this gene generates two transcript variants which encode different isoforms. Also there is possibility for the usage of multiple polyadenylation sites for this gene.
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Protein Aliases: APC-stimulated guanine nucleotide exchange factor; APC-stimulated guanine nucleotide exchange factor 1; Asef; DKFZp434G2016; Rho guanine nucleotide exchange factor (GEF) 4; Rho guanine nucleotide exchange factor 4
Gene Aliases: 9330140K16Rik; ARHGEF4; ASEF; ASEF1; ENSMUSG00000070955; GEF4; KIAA1112; STM6
UniProt ID: (Human) Q9NR80, (Mouse) Q7TNR9
Entrez Gene ID: (Human) 50649, (Rat) 301334, (Mouse) 226970
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