Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: AVCMQFVRK ENLLSLACQH QFCRSCWEQH CSVLVKDGVG VGVSCMAQDC PLRTPEDFVF PLLPNEELRE KYRRYLFRDY VESHYQLQLC PGADCPMVIR VQEPRARRVQ CNRCNEVFCF KCRQMYHAPT DCATIRKWLT KCADDSETAN YISAHTKDCP KCNICIEKNG GCNHMQCSKC KHDFCWMCLG DWKTHGSEYY ECSRYKENPD IVNQSQQAQA REALKKYLFY FERWENHNKS LQLEAQTYQR IHEKIQERVM NNLGTWIDWQ YLQNAAKLLA KCRYTLQYTY PYAYYMESGP RKKLFEYQQA QLEAEIENLS WKVERADSYD RGDLENQMHI AEQRRRTLLK DFHDT (140-493 aa encoded by BC000422)
E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: all-trans retinoic acid inducible RING finger; ARI-2; ariadne 2; ariadne homolog 2; E3 ubiquitin-protein ligase ARIH2; FLJ10938; FLJ33921; OTTHUMP00000210388; protein ariadne-2 homolog; RING-type E3 ubiquitin transferase ARIH2; Triad1 protein; UbcM4-interacting protein 48
Gene Aliases: AI843547; ARI2; ARIH2; HT005; TRIAD1; UIP48
UniProt ID: (Human) O95376, (Mouse) Q9Z1K6
Entrez Gene ID: (Human) 10425, (Mouse) 23807, (Rat) 316005
Molecular Function:
ubiquitin-protein ligase
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