Product References
Deficiency of Perry syndrome-associated p150Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.
NPJ Parkinson's disease
Yu J,Yang X,Zheng J,Sgobio C,Sun L,Cai H
Tue Mar 07 00:00:00 EST 2023
GGC repeat expansion in NOTCH2NLC induces dysfunction in ribosome biogenesis and translation.
Brain : a journal of neurology
Fan Y,Li MJ,Yang J,Li SJ,Hao XY,Li JD,Wang YC,Tang MB,Zhang C,Shi JJ,Ma DR,Guo MN,Liu F,Shen S,Yao DB,Zuo CY,Mao CY,Hu ZW,Zhang S,Yang ZH,Guo GY,Yang JH,Xia ZP,Xu YM,Shi CH
Tue Aug 01 00:00:00 EDT 2023
Large neutral amino acid levels tune perinatal neuronal excitability and survival.
Cell
Knaus LS,Basilico B,Malzl D,Gerykova Bujalkova M,Smogavec M,Schwarz LA,Gorkiewicz S,Amberg N,Pauler FM,Knittl-Frank C,Tassinari M,Maulide N,Rülicke T,Menche J,Hippenmeyer S,Novarino G
Thu Apr 27 00:00:00 EDT 2023
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Environmental toxicology
Li L,Jin RJ,Ji L
Wed May 10 00:00:00 EDT 2023
1,25(OH)2 D3 induced vitamin D receptor signaling negatively regulates endoplasmic reticulum-associated degradation (ERAD) and androgen receptor signaling in human prostate cancer cells.
Cellular signalling
Erzurumlu Y,Aydogdu E,Dogan HK,Catakli D,Muhammed MT,Buyuksandic B
Wed Mar 01 00:00:00 EST 2023
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Translational stroke research
Lu D,Liu Y,Huang H,Hu M,Li T,Wang S,Shen S,Wu R,Cai W,Lu T,Lu Z
Fri Dec 01 00:00:00 EST 2023
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Molecular oncology
Luo G,Aldridge K,Chen T,Aslot V,Kim BG,Han EH,Singh N,Li S,Xiao TS,Sporn MB,Letterio JJ
Fri Dec 01 00:00:00 EST 2023
Hyperbaric oxygen rapidly improves tissue-specific insulin sensitivity and mitochondrial capacity in humans with type 2 diabetes: a randomised placebo-controlled crossover trial.
Diabetologia
Sarabhai T,Mastrototaro L,Kahl S,Bönhof GJ,Jonuscheit M,Bobrov P,Katsuyama H,Guthoff R,Wolkersdorfer M,Herder C,Meuth SG,Dreyer S,Roden M
Sun Jan 01 00:00:00 EST 2023
The effect of tauroursodeoxycholic Acid (TUDCA) treatment on placental endoplasmic reticulum (ER) stress in a rat model of advanced maternal age.
PloS one
Pasha M,Kirschenman R,Wooldridge A,Spaans F,Cooke CM,Davidge ST
Mon Apr 10 00:00:00 EDT 2023
Inhibition of ATF4-mediated elevation of both autophagy and AKT/mTOR was involved in antitumorigenic activity of curcumin.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Yang J,Bao S,Luo S,Jiang L,Li Q,Kong Y,Cao J
Wed Mar 01 00:00:00 EST 2023
Combined inhibition of BCL-2 and MCL-1 overcomes BAX deficiency-mediated resistance of TP53-mutant acute myeloid leukemia to individual BH3 mimetics.
Blood cancer journal
Carter BZ,Mak PY,Tao W,Ayoub E,Ostermann LB,Huang X,Loghavi S,Boettcher S,Nishida Y,Ruvolo V,Hughes PE,Morrow PK,Haferlach T,Kornblau S,Muftuoglu M,Andreeff M
Mon Apr 24 00:00:00 EDT 2023
Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson's disease.
Frontiers in neuroscience
Mubariz F,Saadin A,Lingenfelter N,Sarkar C,Banerjee A,Lipinski MM,Awad O
Fri Jul 14 00:00:00 EDT 2023
Amino acids downregulate SIRT4 to detoxify ammonia through the urea cycle.
Nature metabolism
Hu SH,Feng YY,Yang YX,Ma HD,Zhou SX,Qiao YN,Zhang KH,Zhang L,Huang L,Yuan YY,Lin Y,Zhang XY,Li Y,Li HT,Zhao JY,Xu W,Zhao SM
Sat Apr 01 00:00:00 EDT 2023
β-Cell glucokinase expression was increased in type 2 diabetes subjects with better glycemic control.
Journal of diabetes
Liu J,Fu H,Kang F,Ning G,Ni Q,Wang W,Wang Q
Mon May 01 00:00:00 EDT 2023
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
World journal of gastroenterology
Li WY,Yang F,Li X,Wang LW,Wang Y
Tue Feb 28 00:00:00 EST 2023
The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation.
Cell reports
Curdy N,Lanvin O,Cerapio JP,Pont F,Tosolini M,Sarot E,Valle C,Saint-Laurent N,Lhuillier E,Laurent C,Fournié JJ,Franchini DM
Tue Mar 28 00:00:00 EDT 2023
Tunicamycin induces depression-like behaviors in male rats, accompanied by initiated chaperon-mediated autophagy and decreased synaptic protein expression in the hippocampus.
Neuroscience letters
Yuan G,Xiao L,Xie Y,Si L,Xu H,Xu W,Wang G
Tue Feb 28 00:00:00 EST 2023
Novel neutrophil extracellular trap-related mechanisms in diabetic wounds inspire a promising treatment strategy with hypoxia-challenged small extracellular vesicles.
Bioactive materials
Chu Z,Huang Q,Ma K,Liu X,Zhang W,Cui S,Wei Q,Gao H,Hu W,Wang Z,Meng S,Tian L,Li H,Fu X,Zhang C
Fri Sep 01 00:00:00 EDT 2023
Targeting unfolded protein response using albumin-encapsulated nanoparticles attenuates temozolomide resistance in glioblastoma.
British journal of cancer
Kiang KM,Tang W,Song Q,Liu J,Li N,Lam TL,Shum HC,Zhu Z,Leung GK
Mon May 01 00:00:00 EDT 2023
Tissue Proteogenomic Landscape Reveals the Role of Uncharacterized SEL1L3 in Progression and Immunotherapy Response in Lung Adenocarcinoma.
Journal of proteome research
Shen CY,Chang WH,Chen YJ,Weng CW,Regmi P,Kier MKK,Su KY,Chang GC,Chen JS,Chen YJ,Yu SL
Fri Apr 07 00:00:00 EDT 2023
Vx-809, a CFTR Corrector, Acts through a General Mechanism of Protein Folding and on the Inflammatory Process.
International journal of molecular sciences
Pecoraro M,Serra A,Pascale M,Franceschelli S
Mon Feb 20 00:00:00 EST 2023
Triiodothyronine positively regulates endoplasmic reticulum-associated degradation (ERAD) and promotes androgenic signaling in androgen-dependent prostate cancer cells.
Cellular signalling
Erzurumlu Y,Muhammed MT
Fri Sep 01 00:00:00 EDT 2023
The PERK/ATF4/CHOP signaling branch of the unfolded protein response mediates cisplatin-induced ototoxicity in hair cells.
Drug and chemical toxicology
Qu Y,Zong S,Wang Z,Du P,Wen Y,Li H,Wu N,Xiao H
Wed Mar 01 00:00:00 EST 2023
Protective Effects of Selenium Nanoparticles against Bisphenol A-Induced Toxicity in Porcine Intestinal Epithelial Cells.
International journal of molecular sciences
Pan Z,Huang J,Hu T,Zhang Y,Zhang L,Zhang J,Cui D,Li L,Wang J,Wu Q
Fri Apr 14 00:00:00 EDT 2023
Anoikis patterns exhibit distinct prognostic and immune landscapes in Osteosarcoma.
International immunopharmacology
Zhang Z,Zhu Z,Fu J,Liu X,Mi Z,Tao H,Fan H
Wed Feb 01 00:00:00 EST 2023
Anoikis patterns exhibit distinct prognostic and immune landscapes in Osteosarcoma.
International immunopharmacology
Zhang Z,Zhu Z,Fu J,Liu X,Mi Z,Tao H,Fan H
Wed Feb 01 00:00:00 EST 2023
Dexamethasone-stimulated glucocorticoid receptor signaling positively regulates the endoplasmic reticulum-associated degradation (ERAD) mechanism in hepatocellular carcinoma cells.
Steroids
Erzurumlu Y,Dogan HK,Cataklı D
Sat Jul 01 00:00:00 EDT 2023
Augmenting hematoma-scavenging capacity of innate immune cells by CDNF reduces brain injury and promotes functional recovery after intracerebral hemorrhage.
Cell death & disease
Tseng KY,Stratoulias V,Hu WF,Wu JS,Wang V,Chen YH,Seelbach A,Huttunen HJ,Kulesskaya N,Pang CY,Chou JL,Lindahl M,Saarma M,Huang LC,Airavaara M,Liew HK
Wed Feb 15 00:00:00 EST 2023
PDIA4 confers resistance to ferroptosis via induction of ATF4/SLC7A11 in renal cell carcinoma.
Cell death & disease
Kang L,Wang D,Shen T,Liu X,Dai B,Zhou D,Shen H,Gong J,Li G,Hu Y,Wang P,Mi X,Zhang Y,Tan X
Sat Mar 11 00:00:00 EST 2023
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
Biochemical pharmacology
Li Y,She W,Guo T,Huang T,Liu Y,Liu P,Xu X,Wang X,Wang M,Yu C,Liu Y,Wei Y
Wed Feb 01 00:00:00 EST 2023
Autophagosomes Defeat Ferroptosis by Decreasing Generation and Increasing Discharge of Free Fe2+ in Skin Repair Cells to Accelerate Diabetic Wound Healing.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cui S,Liu X,Liu Y,Hu W,Ma K,Huang Q,Chu Z,Tian L,Meng S,Su J,Zhang W,Li H,Fu X,Zhang C
Fri Sep 01 00:00:00 EDT 2023
Endoplasmic reticulum stress promotes sepsis-induced muscle atrophy via activation of STAT3 and Smad3.
Journal of cellular physiology
Zheng Y,Dai H,Chen R,Zhong Y,Zhou C,Wang Y,Zhan C,Luo J
Wed Mar 01 00:00:00 EST 2023
Potent carotenoid astaxanthin expands the anti-cancer activity of cisplatin in human prostate cancer cells.
Journal of natural medicines
Erzurumlu Y,Catakli D,Dogan HK
Thu Jun 01 00:00:00 EDT 2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen Y,Guo Y,Li S,Xu J,Ning W,Zhao C,Wang J,Qu Y,Zhang M,Zhou W,Cui Q,Zhang H
Sun Jan 01 00:00:00 EST 2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen Y,Guo Y,Li S,Xu J,Ning W,Zhao C,Wang J,Qu Y,Zhang M,Zhou W,Cui Q,Zhang H
Sun Jan 01 00:00:00 EST 2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen Y,Guo Y,Li S,Xu J,Ning W,Zhao C,Wang J,Qu Y,Zhang M,Zhou W,Cui Q,Zhang H
Sun Jan 01 00:00:00 EST 2023
Remdesivir inhibits the progression of glioblastoma by enhancing endoplasmic reticulum stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chen Y,Guo Y,Li S,Xu J,Ning W,Zhao C,Wang J,Qu Y,Zhang M,Zhou W,Cui Q,Zhang H
Sun Jan 01 00:00:00 EST 2023
The interaction between Hsp90-mediated unfolded protein response and autophagy contributes to As3+/ Se4+ combination-induced apoptosis of acute promyelocytic leukemia cells.
Toxicology and applied pharmacology
Chang J,Yan S,Geng Z,Wang Z
Mon May 15 00:00:00 EDT 2023
Atp7b deficiency induces zebrafish eye developmental defects.
Metallomics : integrated biometal science
Wu Y,Liu W,Li L,Tai Z,Gao B,Liu JX
Tue May 02 00:00:00 EDT 2023
TIAR and FMRP shape pro-survival nascent proteome of leukemia cells in the bone marrow microenvironment.
iScience
Wolczyk M,Serwa R,Kominek A,Klejman A,Milek J,Chwałek M,Turos-Korgul L,Charzyńska A,Dabrowski M,Dziembowska M,Skorski T,Piwocka K,Podszywalow-Bartnicka P
Fri Apr 21 00:00:00 EDT 2023
Apigenin improves cytotoxicity of antiretroviral drugs against HTLV-1 infected cells through the modulation of AhR signaling.
NeuroImmune pharmacology and therapeutics
Sales D,Lin E,Stoffel V,Dickson S,Khan ZK,Beld J,Jain P
Sat Mar 25 00:00:00 EDT 2023
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
BMC molecular and cell biology
Chen J,Lei C,Zhang H,Huang X,Yang Y,Liu J,Jia Y,Shi H,Zhang Y,Zhang J,Du J
Fri Mar 03 00:00:00 EST 2023
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Chemico-biological interactions
Li J,Bai J,Si X,Jia H,Wu Z
Sat Apr 01 00:00:00 EDT 2023
Xinfuli granule alleviates metabolic remodeling through inhibition of endoplasmic reticulum stress and mitochondrial injury in heart failure.
Journal of ethnopharmacology
Su YN,Lu PP,Yan SY,Guo XT,Ma J,Guo CX,Ma LH
Wed Mar 01 00:00:00 EST 2023
Spatial position is a key determinant of N-glycan functionality of the scavenger receptor cysteine-rich domain of human hepsin.
The FEBS journal
Sun S,Hu K,Wang L,Liu M,Zhang Y,Dong N,Wu Q
Tue Aug 01 00:00:00 EDT 2023
Translation regulation of specific mRNAs by RPS26 C-terminal RNA-binding tail integrates energy metabolism and AMPK-mTOR signaling.
Nucleic acids research
Havkin-Solomon T,Fraticelli D,Bahat A,Hayat D,Reuven N,Shaul Y,Dikstein R
Mon May 22 00:00:00 EDT 2023
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Tissue & cell
Cui Z,Qin R,Feng J,Liu Y,Zhou X,Qin X,Li Y,Zhang Z,He X
Tue Aug 01 00:00:00 EDT 2023
Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer.
Journal of experimental & clinical cancer research : CR
Zhou F,Gao H,Shang L,Li J,Zhang M,Wang S,Li R,Ye L,Yang S
Mon Jun 19 00:00:00 EDT 2023
Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer.
Journal of experimental & clinical cancer research : CR
Zhou F,Gao H,Shang L,Li J,Zhang M,Wang S,Li R,Ye L,Yang S
Mon Jun 19 00:00:00 EDT 2023
The cytotoxic activity of carfilzomib together with nelfinavir is superior to the bortezomib/nelfinavir combination in non-small cell lung carcinoma.
Scientific reports
Besse L,Kraus M,Besse A,Driessen C,Tarantino I
Fri Mar 17 00:00:00 EDT 2023
Tanshinone IIA ameliorates experimental diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress in cardiomyocytes via SIRT1.
Phytotherapy research : PTR
Wu S,Lu D,Gajendran B,Hu Q,Zhang J,Wang S,Han M,Xu Y,Shen X
Tue Aug 01 00:00:00 EDT 2023
Zinc deficiency causes oxidative stress, endoplasmic reticulum stress, apoptosis and inflammation in hepatocytes in grass carp.
Fish & shellfish immunology
Cui J,Xu T,Lv H,Guo MY
Tue Aug 01 00:00:00 EDT 2023
Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress.
Cellular and molecular life sciences : CMLS
Hu Y,Qi C,Shi J,Tan W,Zhao Z,Xu Y,Wu H,Zhang Z
Thu Mar 23 00:00:00 EDT 2023
Palmitic acid-induced ferroptosis via CD36 activates ER stress to break calcium-iron balance in colon cancer cells.
The FEBS journal
Kuang H,Sun X,Liu Y,Tang M,Wei Y,Shi Y,Li R,Xiao G,Kang J,Wang F,Peng J,Xu H,Zhou F
Sat Jul 01 00:00:00 EDT 2023
Ribosome changes reprogram translation for chemosurvival in G0 leukemic cells.
Science advances
Datta C,Truesdell SS,Wu KQ,Bukhari SIA,Ngue H,Buchanan B,Le Tonqueze O,Lee S,Kollu S,Granovetter MA,Boukhali M,Kreuzer J,Batool MS,Balaj L,Haas W,Vasudevan S
Fri Oct 28 00:00:00 EDT 2022
4-hydroxybenzophenone exposure inhibits mouse hippocampal neural stem cell proliferation in vitro by upregulating Cxcl1.
Toxicology in vitro : an international journal published in association with BIBRA
Lin Y,He M,Zeng X,Sheng X,Wang S,Cui F
Mon Aug 01 00:00:00 EDT 2022
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.
International journal of molecular sciences
Cheng M,Yu H,Kong Q,Wang B,Shen L,Dong D,Sun L
Tue Jan 25 00:00:00 EST 2022
Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress.
Redox biology
Ge X,He Z,Cao C,Xue T,Jing J,Ma R,Zhao W,Liu L,Jueraitetibaike K,Ma J,Feng Y,Qian Z,Zou Z,Chen L,Fu C,Song N,Yao B
Mon Aug 01 00:00:00 EDT 2022
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Environmental toxicology and pharmacology
Xu Q,Zhou L,Ri H,Li X,Zhang X,Qi W,Ye L
Tue Nov 01 00:00:00 EDT 2022
Increased Mobile Zinc Regulates Retinal Ganglion Cell Survival via Activating Mitochondrial OMA1 and Integrated Stress Response.
Antioxidants (Basel, Switzerland)
Tang J,Liu Z,Han J,Xue J,Liu L,Lin J,Wu C,Zhang Q,Wu S,Liu C,Huang H,Fu Y,Li M,Zhuo Y,Li Y
Mon Oct 10 00:00:00 EDT 2022
Increased Mobile Zinc Regulates Retinal Ganglion Cell Survival via Activating Mitochondrial OMA1 and Integrated Stress Response.
Antioxidants (Basel, Switzerland)
Tang J,Liu Z,Han J,Xue J,Liu L,Lin J,Wu C,Zhang Q,Wu S,Liu C,Huang H,Fu Y,Li M,Zhuo Y,Li Y
Mon Oct 10 00:00:00 EDT 2022
Inhibition of the integrated stress response reverses oxidative stress damage-induced postoperative cognitive dysfunction.
Frontiers in cellular neuroscience
Jiang L,Dong R,Xu M,Liu Y,Xu J,Ma Z,Xia T,Gu X
Tue Oct 11 00:00:00 EDT 2022
Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR.
Cell reports
Krokowski D,Jobava R,Szkop KJ,Chen CW,Fu X,Venus S,Guan BJ,Wu J,Gao Z,Banaszuk W,Tchorzewski M,Mu T,Ropelewski P,Merrick WC,Mao Y,Sevval AI,Miranda H,Qian SB,Manifava M,Ktistakis NT,Vourekas A,Jankowsky E,Topisirovic I,Larsson O,Hatzoglou M
Tue Jul 19 00:00:00 EDT 2022
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.
Oncogene
Zhang Y,Wu J,Fu Y,Yu R,Su H,Zheng Q,Wu H,Zhou S,Wang K,Zhao J,Shen S,Xu G,Wang L,Yan C,Zou X,Lv Y,Zhang S
Wed Jun 01 00:00:00 EDT 2022
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.
Oncogene
Zhang Y,Wu J,Fu Y,Yu R,Su H,Zheng Q,Wu H,Zhou S,Wang K,Zhao J,Shen S,Xu G,Wang L,Yan C,Zou X,Lv Y,Zhang S
Wed Jun 01 00:00:00 EDT 2022
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.
Oncogene
Zhang Y,Wu J,Fu Y,Yu R,Su H,Zheng Q,Wu H,Zhou S,Wang K,Zhao J,Shen S,Xu G,Wang L,Yan C,Zou X,Lv Y,Zhang S
Wed Jun 01 00:00:00 EDT 2022
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.
Oncogene
Zhang Y,Wu J,Fu Y,Yu R,Su H,Zheng Q,Wu H,Zhou S,Wang K,Zhao J,Shen S,Xu G,Wang L,Yan C,Zou X,Lv Y,Zhang S
Wed Jun 01 00:00:00 EDT 2022
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Molecular cell
Jiang B,Zhang J,Zhao G,Liu M,Hu J,Lin F,Wang J,Zhao W,Ma H,Zhang C,Wu C,Yao L,Liu Q,Chen X,Cao Y,Zheng Y,Zhang C,Han A,Lin D,Li Q
Thu May 19 00:00:00 EDT 2022
Peste des petits ruminants virus induces ERS-mediated autophagy to promote virus replication.
Veterinary microbiology
Wen B,Yang L,Guo J,Chang W,Wei S,Yu S,Qi X,Xue Q,Wang J
Fri Jul 01 00:00:00 EDT 2022
Jolkinolide B sensitizes bladder cancer to mTOR inhibitors via dual inhibition of Akt signaling and autophagy.
Cancer letters
Sang J,Gan L,Zou MF,Lin ZJ,Fan RZ,Huang JL,Li W,Tang GH,Yin S
Tue Feb 01 00:00:00 EST 2022
Elaiophylin triggers paraptosis and preferentially kills ovarian cancer drug-resistant cells by inducing MAPK hyperactivation.
Signal transduction and targeted therapy
Li GN,Zhao XJ,Wang Z,Luo MS,Shi SN,Yan DM,Li HY,Liu JH,Yang Y,Tan JH,Zhang ZY,Chen RQ,Lai HL,Huang XY,Zhou JF,Ma D,Fang Y,Gao QL
Mon Sep 12 00:00:00 EDT 2022
Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy.
iScience
Kaur N,Ruiz-Velasco A,Raja R,Howell G,Miller JM,Abouleisa RRE,Ou Q,Mace K,Hille SS,Frey N,Binder P,Smith CP,Fachim H,Soran H,Swanton E,Mohamed TMA,Müller OJ,Wang X,Chernoff J,Cartwright EJ,Liu W
Fri Mar 18 00:00:00 EDT 2022
Porcine epidemic diarrhea virus infection induces endoplasmic reticulum stress and unfolded protein response in jejunal epithelial cells of weaned pigs.
Veterinary pathology
Chen YM,Gabler NK,Burrough ER
Sat Jan 01 00:00:00 EST 2022
Qingfei Tongluo Formula Mitigates Mycoplasma pneumoniae Infection via the PERK Signaling Pathway.
Disease markers
Liu X,Wang M,Kan Q,Lin Y,Jiang Z
Wed Aug 23 00:00:00 EDT 2023
STING1 is essential for an RNA-virus triggered autophagy.
Autophagy
Zhang R,Qin X,Yang Y,Zhu X,Zhao S,Zhang Z,Su Q,Zhao Z,Yin X,Meng X,Zhang Z,Li Y
Fri Apr 01 00:00:00 EDT 2022
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
PeerJ
Zhang L,Li C,Fu L,Yu Z,Xu G,Zhou J,Shen M,Feng Z,Zhu H,Xie T,Zhou L,Zhou X
Fri Jan 06 00:00:00 EST 2023
TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF.
International journal of molecular sciences
Wang L,Zhao W,Xia C,Li Z,Zhao W,Xu K,Wang N,Lian H,Rosas IO,Yu G
Sun Dec 11 00:00:00 EST 2022
Jujuboside A ameliorates high fat diet and streptozotocin induced diabetic nephropathy via suppressing oxidative stress, apoptosis, and enhancing autophagy.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Zhong Y,Luo R,Liu Q,Zhu J,Lei M,Liang X,Wang X,Peng X
Sat Jan 01 00:00:00 EST 2022
Nutritional deficiency induces nucleus pulposus cell apoptosis via the ATF4-PKM2-AKT signal ¿axis.
BMC musculoskeletal disorders
Zhou N,Shen B,Bai C,Ma L,Wang S,Wu D
Wed Nov 02 00:00:00 EDT 2022
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response.
FEBS open bio
Yamashita K,Haraguchi M,Yano M
Thu Dec 01 00:00:00 EST 2022
Exercise and Metformin Intervention Prevents Lipotoxicity-Induced Hepatocyte Apoptosis by Alleviating Oxidative and ER Stress and Activating the AMPK/Nrf2/HO-1 Signaling Pathway in db/db Mice.
Oxidative medicine and cellular longevity
Zhang Y,Liu Y,Liu X,Yuan X,Xiang M,Liu J,Zhang L,Zhu S,Lu J,Tang Q,Cheng S
Tue Sep 20 00:00:00 EDT 2022
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
International journal of biological sciences
Gou W,Luo N,Yu B,Wu H,Wu S,Tian C,Guo J,Ning H,Bi C,Wei H,Hou W,Li Y
Thu Apr 14 00:00:00 EDT 2022
Involvement of increased endoplasmic reticulum stress in the development of cataracts in BALB.NCT-Cpoxnct mice.
Experimental eye research
Liu C,Miyahara H,Dai J,Cui X,Li Y,Kang X,Higuchi K,Mori M
Tue Feb 01 00:00:00 EST 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
A Novel ER Stress Mediator TMTC3 Promotes Squamous Cell Carcinoma Progression by Activating GRP78/PERK Signaling Pathway.
International journal of biological sciences
Yuan H,Zhao Z,Guo Z,Ma L,Han J,Song Y
Mon Aug 22 00:00:00 EDT 2022
Cellular responses to halofuginone reveal a vulnerability of the GCN2 branch of the integrated stress response.
The EMBO journal
Pitera AP,Szaruga M,Peak-Chew SY,Wingett SW,Bertolotti A
Wed Jun 01 00:00:00 EDT 2022
Peste des Petits Ruminants Virus Upregulates STING to Activate ATF6-Mediated Autophagy.
Journal of virology
Zhang R,Lin H,You Q,Zhang Z,Bai L,Chen F,Zhu X,Zhang Z,Li Y
Wed Oct 26 00:00:00 EDT 2022
Mechanism of Endoplasmic Reticulum Stress Pathway in the Osteogenic Phenotypic Transformation of Aortic Valve Interstitial Cells.
Frontiers in endocrinology
Tao Y,Geng Y,Dang W,Xu X,Zhao H,Zou L,Li Y
Fri Apr 01 00:00:00 EDT 2022
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress.
BioMed research international
Qiu Y,Li C,Zhang B
Fri Apr 08 00:00:00 EDT 2022
SCF-SKP2 E3 ubiquitin ligase links mTORC1/ER stress/ISR with YAP activation in murine renal cystogenesis.
The Journal of clinical investigation
Panda DK,Bai X,Zhang Y,Stylianesis NA,Koromilas AE,Lipman ML,Karaplis AC
Thu Dec 15 00:00:00 EST 2022
Mitochondrial Oxidative Stress Promotes Cardiac Remodeling in Myocardial Infarction through the Activation of Endoplasmic Reticulum Stress.
Antioxidants (Basel, Switzerland)
Souza-Neto FV,Islas F,Jiménez-González S,Luaces M,Ramchandani B,Romero-Miranda A,Delgado-Valero B,Roldan-Molina E,Saiz-Pardo M,Cerón-Nieto MÁ,Ortega-Medina L,Martínez-Martínez E,Cachofeiro V
Thu Jun 23 00:00:00 EDT 2022
African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-κB Signaling Pathway.
Viruses
Wang Q,Zhou L,Wang J,Su D,Li D,Du Y,Yang G,Zhang G,Chu B
Tue Feb 15 00:00:00 EST 2022
Attenuation of Activated eIF2α Signaling by ISRIB Treatment After Spinal Cord Injury Improves Locomotor Function.
Journal of molecular neuroscience : MN
Chang L,Liu X,Chen J,Liu H,Wang G,Wang G,Liao X,Shen X
Tue Mar 01 00:00:00 EST 2022
Impaired Restoration of Global Protein Synthesis Contributes to Increased Vulnerability to Acute ER Stress Recovery in Huntington's Disease.
Cellular and molecular neurobiology
Xu H,Bensalel J,Capobianco E,Lu ML,Wei J
Tue Nov 01 00:00:00 EDT 2022
Integrated stress response is involved in the 24(S)-hydroxycholesterol-induced unconventional cell death mechanism.
Cell death discovery
Urano Y,Osaki S,Chiba R,Noguchi N
Tue Oct 04 00:00:00 EDT 2022
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Cellular and molecular gastroenterology and hepatology
Xie M,Mak JWY,Yu H,Cheng CTY,Chan HCH,Chan TT,Lau LHS,Wong MTL,Ko WH,Jiang L,Yao X
Mon Jul 25 00:00:00 EDT 2022
Resveratrol protected acrolein-induced ferroptosis and insulin secretion dysfunction via ER-stress- related PERK pathway in MIN6 cells.
Toxicology
Zhang X,Jiang L,Chen H,Wei S,Yao K,Sun X,Yang G,Jiang L,Zhang C,Wang N,Wang Y,Liu X
Sat Jan 15 00:00:00 EST 2022
Inhibition of the miR-193b-3p protects against oxidized low-density lipoprotein-induced HUVECs injury by upregulating ALDH2.
Cell biology international
Bai Y,Wang M,Yang Y,Liu X,Chen Q,Guo Z
Tue Feb 01 00:00:00 EST 2022
Inhibition of the miR-193b-3p protects against oxidized low-density lipoprotein-induced HUVECs injury by upregulating ALDH2.
Cell biology international
Bai Y,Wang M,Yang Y,Liu X,Chen Q,Guo Z
Tue Feb 01 00:00:00 EST 2022
Inhibition of human peptide deformylase by actinonin sensitizes glioblastoma cells to temozolomide chemotherapy.
Experimental cell research
Lan B,Zhao H,He Y,Zhao Z,Wang N,Gao Y
Tue Nov 15 00:00:00 EST 2022
Age-related endoplasmic reticulum stress represses testosterone synthesis via attenuation of the circadian clock in Leydig cells.
Theriogenology
Gao L,Gao D,Zhang J,Li C,Wu M,Xiao Y,Yang L,Ma T,Wang X,Zhang M,Yang D,Pan T,Zhang H,Wang A,Jin Y,Chen H
Thu Sep 01 00:00:00 EDT 2022
Effects of natural 24-epibrassinolide on inducing apoptosis and restricting metabolism in hepatocarcinoma cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Zhou H,Zhuang W,Huang H,Ma N,Lei J,Jin G,Wu S,Zhou S,Zhao X,Lan L,Xia H,Shangguan F
Thu Dec 01 00:00:00 EST 2022
Aging Impairs Adaptive Unfolded Protein Response and Drives Beta Cell Dedifferentiation in Humans.
The Journal of clinical endocrinology and metabolism
Song J,Ni Q,Sun J,Xie J,Liu J,Ning G,Wang W,Wang Q
Fri Nov 25 00:00:00 EST 2022
Induction of IL-6Rα by ATF3 enhances IL-6 mediated sorafenib and regorafenib resistance in hepatocellular carcinoma.
Cancer letters
Dai Z,Wang X,Peng R,Zhang B,Han Q,Lin J,Wang J,Lin J,Jiang M,Liu H,Lee TH,Lu KP,Zheng M
Sat Jan 01 00:00:00 EST 2022
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Ecotoxicology and environmental safety
Zeng HF,Xu J,Wang XL,Li SJ,Han ZY
Fri Apr 15 00:00:00 EDT 2022
Hepatocyte-Derived Prostaglandin E2-Modulated Macrophage M1-Type Polarization via mTOR-NPC1 Axis-Regulated Cholesterol Transport from Lysosomes to the Endoplasmic Reticulum in Hepatitis B Virus x Protein-Related Nonalcoholic Steatohepatitis.
International journal of molecular sciences
Lan Y,Qian B,Huang HY,Wang P,Li T,Yuan Q,Zhang HY,Lin YC,Lin ZN
Sat Oct 01 00:00:00 EDT 2022
Hepatocyte-Derived Prostaglandin E2-Modulated Macrophage M1-Type Polarization via mTOR-NPC1 Axis-Regulated Cholesterol Transport from Lysosomes to the Endoplasmic Reticulum in Hepatitis B Virus x Protein-Related Nonalcoholic Steatohepatitis.
International journal of molecular sciences
Lan Y,Qian B,Huang HY,Wang P,Li T,Yuan Q,Zhang HY,Lin YC,Lin ZN
Sat Oct 01 00:00:00 EDT 2022
Cooperation of ATF4 and CTCF promotes adipogenesis through transcriptional regulation.
Cell biology and toxicology
Chen Y,He R,Han Z,Wu Y,Wang Q,Zhu X,Huang Z,Ye J,Tang Y,Huang H,Chen J,Shan H,Xiao F
Sat Oct 01 00:00:00 EDT 2022
C9orf72 regulates the unfolded protein response and stress granule formation by interacting with eIF2α.
Theranostics
Zheng W,Wang K,Wu Y,Yan G,Zhang C,Li Z,Wang L,Chen S
Thu Dec 08 00:00:00 EST 2022
Upregulation of ATF4-LAMP3 Axis by ORF45 Facilitates Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus.
Journal of virology
Sun Q,Wang F,Chen Q,Sarid R,Li X,Kuang E
Wed Dec 14 00:00:00 EST 2022
A systems biological analysis of the ATF4-GADD34-CHOP regulatory triangle upon endoplasmic reticulum stress.
FEBS open bio
Márton M,Bánhegyi G,Gyöngyösi N,Kálmán EÉ,Pettkó-Szandtner A,Káldi K,Kapuy O
Tue Nov 01 00:00:00 EDT 2022
Zebrafish cox17 modulates primitive erythropoiesis via regulation of mitochondrial metabolism to facilitate hypoxia tolerance.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Li L,Chen M,Liu W,Tai P,Liu X,Liu JX
Tue Nov 01 00:00:00 EDT 2022
Inhibition of USP14 influences alphaherpesvirus proliferation by degrading viral VP16 protein via ER stress-triggered selective autophagy.
Autophagy
Ming SL,Zhang S,Wang Q,Zeng L,Zhou LY,Wang MD,Ma YX,Han LQ,Zhong K,Zhu HS,Bai YL,Yang GY,Wang J,Chu BB
Mon Aug 01 00:00:00 EDT 2022
Dioscin relieves diabetic nephropathy via suppressing oxidative stress and apoptosis, and improving mitochondrial quality and quantity control.
Food & function
Zhong Y,Liu J,Sun D,Guo T,Yao Y,Xia X,Shi C,Peng X
Mon Mar 21 00:00:00 EDT 2022
Glaucocalyxin A impairs tumor growth via amplification of the ATF4/CHOP/CHAC1 cascade in human oral squamous cell carcinoma.
Journal of ethnopharmacology
Wang X,He MJ,Chen XJ,Bai YT,Zhou G
Mon May 23 00:00:00 EDT 2022
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Photodermatology, photoimmunology & photomedicine
Wang J,Wang Q,Chen P,Li Q,Li Z,Xu M,Zeng K,Li C
Fri Jul 01 00:00:00 EDT 2022
Combinatorial analysis of translation dynamics reveals eIF2 dependence of translation initiation at near-cognate codons.
Nucleic acids research
Ichihara K,Matsumoto A,Nishida H,Kito Y,Shimizu H,Shichino Y,Iwasaki S,Imami K,Ishihama Y,Nakayama KI
Wed Jul 21 00:00:00 EDT 2021
Citrus alkaline extracts prevent endoplasmic reticulum stress in type II alveolar epithelial cells to ameliorate pulmonary fibrosis via the ATF3/PINK1 pathway.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Wang Z,Feng F,He H,Wu Q,Gu C,Hrovat J,Peng W,Xu Y,Han D,Yang P,Zhou X,Li J,Shan J
Sun Aug 01 00:00:00 EDT 2021
Ferroptosis-related Genes for Overall Survival Prediction in Patients with Colorectal Cancer can be Inhibited by Gallic acid.
International journal of biological sciences
Hong Z,Tang P,Liu B,Ran C,Yuan C,Zhang Y,Lu Y,Duan X,Yang Y,Wu H
Fri Jan 21 00:00:00 EST 2022
Integrated Structural Analysis of N-Glycans and Free Oligosaccharides Allows for a Quantitative Evaluation of ER Stress.
Biochemistry
Fujitani N,Ariki S,Hasegawa Y,Uehara Y,Saito A,Takahashi M
Tue Jun 01 00:00:00 EDT 2021
Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4.
Autophagy
Huang T,Xu T,Wang Y,Zhou Y,Yu D,Wang Z,He L,Chen Z,Zhang Y,Davidson D,Dai Y,Hang C,Liu X,Yan C
Mon Nov 01 00:00:00 EDT 2021
Cassane diterpenoid derivative induces apoptosis in IDH1 mutant glioma cells through the inhibition of glutaminase in vitro and in vivo.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Huang GD,Chen FF,Ma GX,Li WP,Zheng YY,Meng XB,Li ZY,Chen L
Mon Feb 01 00:00:00 EST 2021
Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin.
Molecular metabolism
Byles V,Cormerais Y,Kalafut K,Barrera V,Hughes Hallett JE,Sui SH,Asara JM,Adams CM,Hoxhaj G,Ben-Sahra I,Manning BD
Mon Nov 01 00:00:00 EDT 2021
Downregulation of activating transcription factor 4 attenuates lysophosphatidycholine-induced inflammation via the NF-κB pathway.
European journal of pharmacology
Gong Y,Li Q,Ma Z,Jin T,Lin J,Lv Q,Wang M,Fu G,Xu S
Mon Nov 15 00:00:00 EST 2021
Autophagic Flux Unleashes GATA4-NF-κB Axis to Promote Antioxidant Defense-Dependent Survival of Colorectal Cancer Cells under Chronic Acidosis.
Oxidative medicine and cellular longevity
Liu X,Zhao M,Sun X,Meng Z,Bai X,Gong Y,Xu L,Hao X,Yang T,Wei Z,Zhang X,Guo H,Li P,Liu Q,Gong Y,Shi Y,Shao C
Fri Mar 04 00:00:00 EST 2022
Differential effects of integrase strand transfer inhibitors, elvitegravir and raltegravir, on oligodendrocyte maturation: A role for the integrated stress response.
Glia
Roth LM,Zidane B,Festa L,Putatunda R,Romer M,Monnerie H,Jordan-Sciutto KL,Grinspan JB
Mon Feb 01 00:00:00 EST 2021
RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse.
The Journal of clinical investigation
Cho J,Min HY,Lee HJ,Hyun SY,Sim JY,Noh M,Hwang SJ,Park SH,Boo HJ,Lee HJ,Hong S,Park RW,Shin YK,Hung MC,Lee HY
Mon Jan 04 00:00:00 EST 2021
Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells.
Cancer letters
Sang J,Li W,Diao HJ,Fan RZ,Huang JL,Gan L,Zou MF,Tang GH,Yin S
Thu Jul 01 00:00:00 EDT 2021
Manipulation of the unfolded protein response: A pharmacological strategy against coronavirus infection.
PLoS pathogens
Echavarría-Consuegra L,Cook GM,Busnadiego I,Lefèvre C,Keep S,Brown K,Doyle N,Dowgier G,Franaszek K,Moore NA,Siddell SG,Bickerton E,Hale BG,Firth AE,Brierley I,Irigoyen N
Tue Jun 01 00:00:00 EDT 2021
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis.
Frontiers in cell and developmental biology
Lin Z,Ni L,Teng C,Zhang Z,Wu L,Jin Y,Lu X,Lin Z
Tue Nov 23 00:00:00 EST 2021
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Toxicology
Liu YN,Mu YD,Wang H,Zhang M,Shi YW,Mi G,Peng LX,Chen JH
Wed Dec 01 00:00:00 EST 2021
CTRP1 Attenuates Cerebral Ischemia/Reperfusion Injury via the PERK Signaling Pathway.
Frontiers in cell and developmental biology
Fei H,Xiang P,Luo W,Tan X,Gu C,Liu M,Chen M,Wang Q,Yang J
Tue Aug 24 00:00:00 EDT 2021
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Cell death & disease
Zhao T,Zheng T,Yu H,Hu BH,Hu B,Ma P,Yang Y,Yang N,Hu J,Cao T,Chen G,Yan B,Peshoff M,Hatzoglou M,Geng R,Li B,Zheng QY
Mon Jan 04 00:00:00 EST 2021
Inhibition of eIF2α Phosphorylation by Peste des Petits Ruminant Virus Phosphoprotein Facilitates Viral Replication.
Frontiers in veterinary science
Alfred N,Qian B,Qin X,Yin X,Prajapati M,Dou Y,Li Y,Zhang Z
Sat Jul 24 00:00:00 EDT 2021
Inhibition of eIF2α Phosphorylation by Peste des Petits Ruminant Virus Phosphoprotein Facilitates Viral Replication.
Frontiers in veterinary science
Alfred N,Qian B,Qin X,Yin X,Prajapati M,Dou Y,Li Y,Zhang Z
Sat Jul 24 00:00:00 EDT 2021
Salubrinal Enhances Cancer Cell Death during Glucose Deprivation through the Upregulation of xCT and Mitochondrial Oxidative Stress.
Biomedicines
Chen MC,Hsu LL,Wang SF,Pan YL,Lo JF,Yeh TS,Tseng LM,Lee HC
Sat Aug 28 00:00:00 EDT 2021
The fatty acid elongase ELOVL6 regulates bortezomib resistance in multiple myeloma.
Blood advances
Lipchick BC,Utley A,Han Z,Moparthy S,Yun DH,Bianchi-Smiraglia A,Wolff DW,Fink E,Liu L,Furdui CM,Lee J,Lee KP,Nikiforov MA
Tue Apr 13 00:00:00 EDT 2021
Kaempferol Alleviates Steatosis and Inflammation During Early Non-Alcoholic Steatohepatitis Associated With Liver X Receptor α-Lysophosphatidylcholine Acyltransferase 3 Signaling Pathway.
Frontiers in pharmacology
Xiang H,Shao M,Lu Y,Wang J,Wu T,Ji G
Fri Jul 16 00:00:00 EDT 2021
The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer.
Cancer research
Samanta S,Yang S,Debnath B,Xue D,Kuang Y,Ramkumar K,Lee AS,Ljungman M,Neamati N
Thu Apr 01 00:00:00 EDT 2021
HMGB1 signaling-regulated endoplasmic reticulum stress mediates intestinal ischemia/reperfusion-induced acute renal damage.
Surgery
Lai HJ,Zhan YQ,Qiu YX,Ling YH,Zhang XY,Chang ZN,Zhang YN,Liu ZM,Wen SH
Thu Jul 01 00:00:00 EDT 2021
HMGB1 signaling-regulated endoplasmic reticulum stress mediates intestinal ischemia/reperfusion-induced acute renal damage.
Surgery
Lai HJ,Zhan YQ,Qiu YX,Ling YH,Zhang XY,Chang ZN,Zhang YN,Liu ZM,Wen SH
Thu Jul 01 00:00:00 EDT 2021
Involvement of endoplasmic reticulum stress-activated PERK-eIF2α-ATF4 signaling pathway in T-2 toxin-induced apoptosis of porcine renal epithelial cells.
Toxicology and applied pharmacology
Liu X,Wang Z,Wang X,Yan X,He Q,Liu S,Ye M,Li X,Yuan Z,Wu J,Yi J,Wen L,Li R
Wed Dec 01 00:00:00 EST 2021
iPLA2β Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury.
Cells
Jin T,Lin J,Gong Y,Bi X,Hu S,Lv Q,Chen J,Li X,Chen J,Zhang W,Wang M,Fu G
Wed Jun 09 00:00:00 EDT 2021
Limonin ameliorates dextran sulfate sodium-induced chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and NF-κB signaling.
International immunopharmacology
Song C,Chen J,Li X,Yang R,Cao X,Zhou L,Zhou Y,Ying H,Zhang Q,Sun Y
Fri Jan 01 00:00:00 EST 2021
Inhibition of endoplasmic reticulum stress-related autophagy attenuates MCLR-induced apoptosis in zebrafish testis and mouse TM4 cells.
Ecotoxicology and environmental safety
Wu Z,Wang F,Hu L,Zhang J,Chen D,Zhao S
Wed Sep 15 00:00:00 EDT 2021
Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation.
Cell death & disease
Wei L,Lin Q,Lu Y,Li G,Huang L,Fu Z,Chen R,Zhou Q
Mon Mar 29 00:00:00 EDT 2021
Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation.
Cell death & disease
Wei L,Lin Q,Lu Y,Li G,Huang L,Fu Z,Chen R,Zhou Q
Mon Mar 29 00:00:00 EDT 2021
Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation.
Cell death & disease
Wei L,Lin Q,Lu Y,Li G,Huang L,Fu Z,Chen R,Zhou Q
Mon Mar 29 00:00:00 EDT 2021
Interleukin-15 modulates the response of cortical neurons to ischemia.
Molecular and cellular neurosciences
Nguyen V,Ameri K,Huynh K,Fredkin M,Grona R,Larpthaveesarp A,Gonzalez F,Yeghiazarians Y
Wed Sep 01 00:00:00 EDT 2021
Involvement of kisspeptin in androgen-induced hypothalamic endoplasmic reticulum stress and its rescuing effect in PCOS rats.
Biochimica et biophysica acta. Molecular basis of disease
Yuan C,Huang WQ,Guo JH,Liu XY,Yang JZ,Chen JJ,Wu Y,Ruan YC,Liu JY,Cui YG,Diao FY,Chan HC
Wed Dec 01 00:00:00 EST 2021
Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy.
Nutrition & metabolism
Lu J,Gong Y,Wei X,Yao Z,Yang R,Xin J,Gao L,Shao S
Tue Apr 13 00:00:00 EDT 2021
Overexpression of lncRNA Dancr inhibits apoptosis and enhances autophagy to protect cardiomyocytes from endoplasmic reticulum stress injury via sponging microRNA-6324.
Molecular medicine reports
Li J,Xie J,Wang YZ,Gan YR,Wei L,Ding GW,Ding YH,Xie DX
Mon Feb 01 00:00:00 EST 2021
Inhibition of ER stress attenuates kidney injury and apoptosis induced by 3-MCPD via regulating mitochondrial fission/fusion and Ca2+ homeostasis.
Cell biology and toxicology
Zhong Y,Jin C,Han J,Zhu J,Liu Q,Sun D,Xia X,Peng X
Fri Oct 01 00:00:00 EDT 2021
Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice.
Molecular metabolism
Kawakubo-Yasukochi T,Yano E,Kimura S,Nishinakagawa T,Mizokami A,Hayashi Y,Hatakeyama Y,Ohe K,Yasukochi A,Nakamura S,Jimi E,Hirata M
Wed Dec 01 00:00:00 EST 2021
Central role of TRAP1 in the ameliorative effect of oleanolic acid on the mitochondrial-mediated and endoplasmic reticulum stress-excitated apoptosis induced by ochratoxin A.
Toxicology
Zhang Q,Chen W,Zhang B,Li C,Zhang X,Wang Q,Wang Y,Zhou Q,Li X,Shen XL
Sun Feb 28 00:00:00 EST 2021
Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol-Associated Liver Disease.
Hepatology communications
Ratna A,Lim A,Li Z,Argemi J,Bataller R,Chiosis G,Mandrekar P
Thu Jul 01 00:00:00 EDT 2021
HIV-induced neuroinflammation inhibits oligodendrocyte maturation via glutamate-dependent activation of the PERK arm of the integrated stress response.
Glia
Roth LM,Akay-Espinoza C,Grinspan JB,Jordan-Sciutto KL
Wed Sep 01 00:00:00 EDT 2021
Zonisamide alleviates cardiac hypertrophy in rats by increasing Hrd1 expression and inhibiting endoplasmic reticulum stress.
Acta pharmacologica Sinica
Wu Q,Tian JH,He YX,Huang YY,Huang YQ,Zhang GP,Luo JD,Xue Q,Yu XY,Liu YH
Fri Oct 01 00:00:00 EDT 2021
The Novel Curcumin Derivative 1g Induces Mitochondrial and ER-Stress-Dependent Apoptosis in Colon Cancer Cells by Induction of ROS Production.
Frontiers in oncology
Wang H,Xu Y,Sun J,Sui Z
Fri Jul 02 00:00:00 EDT 2021
Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway.
Aging cell
Liu X,Chen A,Liang Q,Yang X,Dong Q,Fu M,Wang S,Li Y,Ye Y,Lan Z,Chen Y,Ou JS,Yang P,Lu L,Yan J
Tue Jun 01 00:00:00 EDT 2021
Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway.
Frontiers in pharmacology
Sun J,Chen W,Li S,Yang S,Zhang Y,Hu X,Qiu H,Wu J,Xu S,Chu T
Sat Oct 16 00:00:00 EDT 2021
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Frontiers in cardiovascular medicine
Zhang XM,Gu YH,Deng H,Xu ZQ,Zhong ZY,Lyu XJ,Jin HM,Yang XH
Tue Jul 27 00:00:00 EDT 2021
Activating transcription factor 4 mediates adaptation of human glioblastoma cells to hypoxia and temozolomide.
Scientific reports
Lorenz NI,Sittig ACM,Urban H,Luger AL,Engel AL,Münch C,Steinbach JP,Ronellenfitsch MW
Thu Jul 08 00:00:00 EDT 2021
The ameliorative effect of terpinen-4-ol on ER stress-induced vascular calcification depends on SIRT1-mediated regulation of PERK acetylation.
Pharmacological research
Zhang Y,He L,Tu M,Huang M,Chen Y,Pan D,Peng J,Shen X
Sun Aug 01 00:00:00 EDT 2021
The Novel Antitumor Compound HCA Promotes Glioma Cell Death by Inducing Endoplasmic Reticulum Stress and Autophagy.
Cancers
Beteta-Göbel R,Fernández-Díaz J,Arbona-González L,Rodríguez-Lorca R,Torres M,Busquets X,Fernández-García P,Escribá PV,Lladó V
Thu Aug 26 00:00:00 EDT 2021
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Ecotoxicology and environmental safety
Jin H,Hou J,Meng X,Ma T,Wang B,Liu Z,Sha X,Ding J,Han X
Fri Jan 15 00:00:00 EST 2021
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca2+ Homeostasis, and Bcl2 Expression.
Molecular nutrition & food research
Zhong Y,Jin C,Han J,Zhu J,Liu Q,Sun D,Xia X,Zhang Y,Peng X
Sun Aug 01 00:00:00 EDT 2021
Targeted Inhibition of P4HB Promotes Cell Sensitivity to Gemcitabine in Urothelial Carcinoma of the Bladder.
OncoTargets and therapy
Wang X,Bai Y,Zhang F,Yang Y,Feng D,Li A,Yang Z,Li D,Tang Y,Wei X,Wei W,Han P
Sun Apr 17 00:00:00 EDT 2022
Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells.
FEBS open bio
Zhang XM,Wang YZ,Tong JD,Ning XC,Zhou FQ,Yang XH,Jin HM
Fri May 01 00:00:00 EDT 2020
The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy.
Diabetes, metabolic syndrome and obesity : targets and therapy
Xu X,Chen B,Huang Q,Wu Y,Liang T
Sat Apr 16 00:00:00 EDT 2022
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Cell proliferation
Tang Q,Ren L,Liu J,Li W,Zheng X,Wang J,Du G
Wed Jan 01 00:00:00 EST 2020
N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.
International journal of molecular sciences
Xie H,Li X,Yang W,Yu L,Jiang X,Chen Y,Shen Z,Li C,Gu M,Shi L
Thu Aug 13 00:00:00 EDT 2020
4-Phenylbutyrate Prevents Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Heatstroke in the Intestines of Mice.
Shock (Augusta, Ga.)
Cao Y,Liu Z,Xiao W,Gu Z,Xiao G,Yuan F,Chen F,Pei Y,Li H,Su L
Wed Jul 01 00:00:00 EDT 2020
TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation.
American journal of respiratory cell and molecular biology
O'Leary EM,Tian Y,Nigdelioglu R,Witt LJ,Cetin-Atalay R,Meliton AY,Woods PS,Kimmig LM,Sun KA,Gökalp GA,Mutlu GM,Hamanaka RB
Sun Nov 01 00:00:00 EDT 2020
TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation.
American journal of respiratory cell and molecular biology
O'Leary EM,Tian Y,Nigdelioglu R,Witt LJ,Cetin-Atalay R,Meliton AY,Woods PS,Kimmig LM,Sun KA,Gökalp GA,Mutlu GM,Hamanaka RB
Sun Nov 01 00:00:00 EDT 2020
Porcine Circovirus Type 2 ORF5 Protein Induces Autophagy to Promote Viral Replication via the PERK-eIF2α-ATF4 and mTOR-ERK1/2-AMPK Signaling Pathways in PK-15 Cells.
Frontiers in microbiology
Lv J,Jiang Y,Feng Q,Fan Z,Sun Y,Xu P,Hou Y,Zhang X,Fan Y,Xu X,Zhang Y,Guo K
Mon Sep 28 00:00:00 EDT 2020
Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.
Journal of cellular and molecular medicine
Lu F,Lu B,Zhang L,Wen J,Wang M,Zhang S,Li Q,Shu F,Sun Y,Liu N,Peng S,Zhao Y,Dong S,Zhao D,Lu F,Zhang W
Sat Aug 01 00:00:00 EDT 2020
Trehalose reduces bone loss in experimental biliary cirrhosis rats via ERK phosphorylation regulation by enhancing autophagosome formation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Xu X,Wang R,Wu R,Yan W,Shi T,Jiang Q,Shi D
Mon Jun 01 00:00:00 EDT 2020
Trehalose reduces bone loss in experimental biliary cirrhosis rats via ERK phosphorylation regulation by enhancing autophagosome formation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Xu X,Wang R,Wu R,Yan W,Shi T,Jiang Q,Shi D
Mon Jun 01 00:00:00 EDT 2020
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Oxidative medicine and cellular longevity
Cui R,Liu S,Wang C,Liu T,Ren J,Jia Y,Tong Y,Liu C,Zhang J
Thu May 13 00:00:00 EDT 2021
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Redox biology
Wang Y,Chen J,Li S,Zhang X,Guo Z,Hu J,Shao X,Song N,Zhao Y,Li H,Yang G,Xu C,Wei C
Fri May 01 00:00:00 EDT 2020
Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation.
Nature communications
Yuan F,Jiang H,Yin H,Jiang X,Jiao F,Chen S,Ying H,Chen Y,Zhai Q,Guo F
Fri Jun 05 00:00:00 EDT 2020
Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats.
World journal of gastroenterology
Su W,Tai Y,Tang SH,Ye YT,Zhao C,Gao JH,Tuo BG,Tang CW
Tue Jul 28 00:00:00 EDT 2020
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys44 to prevent cardiac structural damage in diabetic cardiomyopathy.
British journal of pharmacology
Sun X,Zhao D,Lu F,Peng S,Yu M,Liu N,Sun Y,Du H,Wang B,Chen J,Dong S,Lu F,Zhang W
Sat Feb 01 00:00:00 EST 2020
Brevilin A Inhibits STAT3 Signaling and Induces ROS-Dependent Apoptosis, Mitochondrial Stress and Endoplasmic Reticulum Stress in MCF-7 Breast Cancer Cells.
OncoTargets and therapy
Saleem MZ,Nisar MA,Alshwmi M,Din SRU,Gamallat Y,Khan M,Ma T
Tue Apr 12 00:00:00 EDT 2022
Paris saponin II-induced paraptosis-associated cell death increased the sensitivity of cisplatin.
Toxicology and applied pharmacology
Man S,Lv P,Cui J,Liu F,Peng L,Ma L,Liu C,Gao W
Sun Nov 01 00:00:00 EDT 2020
Liraglutide protects pancreatic β cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover.
Life sciences
Fu J,Nchambi KM,Wu H,Luo X,An X,Liu D
Wed Jul 01 00:00:00 EDT 2020
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Molecular medicine (Cambridge, Mass.)
Sun X,Liu H,Sun Z,Zhang B,Wang X,Liu T,Pan T,Gao Y,Jiang X,Li H
Tue Nov 10 00:00:00 EST 2020
Perinatal low-dose PBDE-47 exposure hampered thyroglobulin turnover and induced thyroid cell apoptosis by triggering ER stress and lysosomal destabilization contributing to thyroid toxicity in adult female rats.
Journal of hazardous materials
Li P,Gao H,Dong L,Liu L,Zhou G,Luo C,Tian Z,Xia T,Wang A,Zhang S
Mon Jun 15 00:00:00 EDT 2020
Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress.
Neurotoxicity research
Liu Y,Zou GJ,Tu BX,Hu ZL,Luo C,Cui YH,Xu Y,Li F,Dai RP,Bi FF,Li CQ
Sat Aug 01 00:00:00 EDT 2020
Dihydroartemisinin exposure impairs porcine ovarian granulosa cells by activating PERK-eIF2α-ATF4 through endoplasmic reticulum stress.
Toxicology and applied pharmacology
Luo Y,Guo Q,Zhang L,Zhuan Q,Meng L,Fu X,Hou Y
Tue Sep 15 00:00:00 EDT 2020
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.
Cell
Zhao Q,Liu J,Deng H,Ma R,Liao JY,Liang H,Hu J,Li J,Guo Z,Cai J,Xu X,Gao Z,Su S
Thu Oct 01 00:00:00 EDT 2020
Perfluorooctanoic acid activates the unfolded protein response in pancreatic acinar cells.
Journal of biochemical and molecular toxicology
Hocevar SE,Kamendulis LM,Hocevar BA
Sun Nov 01 00:00:00 EDT 2020
Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Pang X,Qiao Q,Vonglorkham S,Feng Z,Pang L,Chen S,Wang D,Lao L,Lin X,Wei J
Tue Sep 01 00:00:00 EDT 2020
The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.
Frontiers in oncology
Yang Z,Huang R,Wei X,Yu W,Min Z,Ye M
Thu Oct 01 00:00:00 EDT 2020
The mRNA levels of heat shock factor 1 are regulated by thermogenic signals via the cAMP-dependent transcription factor ATF3.
The Journal of biological chemistry
Verma N,Perie L,Mueller E
Fri May 01 00:00:00 EDT 2020
Administration of mulberry leaves maintains pancreatic β-cell mass in obese/type 2 diabetes mellitus mouse model.
BMC complementary medicine and therapies
Suthamwong P,Minami M,Okada T,Shiwaku N,Uesugi M,Yokode M,Kamei K
Wed May 06 00:00:00 EDT 2020
Nucleotide-binding oligomerization domain protein 2 deficiency enhances CHOP expression and plaque necrosis in advanced atherosclerotic lesions.
The FEBS journal
Kwon MY,Hwang N,Back SH,Lee SJ,Perrella MA,Chung SW
Fri May 01 00:00:00 EDT 2020
Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca+2 Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells.
Frontiers in pharmacology
Saleem MZ,Alshwmi M,Zhang H,Din SRU,Nisar MA,Khan M,Alam S,Alam G,Jin L,Ma T
Tue Oct 06 00:00:00 EDT 2020
Divergent effects of translation termination factor eRF3A and nonsense-mediated mRNA decay factor UPF1 on the expression of uORF carrying mRNAs and ribosome protein genes.
RNA biology
Aliouat A,Hatin I,Bertin P,François P,Stierlé V,Namy O,Salhi S,Jean-Jean O
Sat Feb 01 00:00:00 EST 2020
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Neuropathology and applied neurobiology
Yue J,Wei YJ,Yang XL,Liu SY,Yang H,Zhang CQ
Tue Dec 01 00:00:00 EST 2020
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Neuropathology and applied neurobiology
Yue J,Wei YJ,Yang XL,Liu SY,Yang H,Zhang CQ
Tue Dec 01 00:00:00 EST 2020
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Neuropathology and applied neurobiology
Yue J,Wei YJ,Yang XL,Liu SY,Yang H,Zhang CQ
Tue Dec 01 00:00:00 EST 2020
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Neuropathology and applied neurobiology
Yue J,Wei YJ,Yang XL,Liu SY,Yang H,Zhang CQ
Tue Dec 01 00:00:00 EST 2020
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Neuropathology and applied neurobiology
Yue J,Wei YJ,Yang XL,Liu SY,Yang H,Zhang CQ
Tue Dec 01 00:00:00 EST 2020
NLRP3 inflammasome and endoplasmic reticulum stress in the epileptogenic zone in temporal lobe epilepsy: molecular insights into their interdependence.
Neuropathology and applied neurobiology
Yue J,Wei YJ,Yang XL,Liu SY,Yang H,Zhang CQ
Tue Dec 01 00:00:00 EST 2020
Prostaglandin F2α Induces Goat Corpus Luteum Regression via Endoplasmic Reticulum Stress and Autophagy.
Frontiers in physiology
Wen X,Liu L,Li S,Lin P,Chen H,Zhou D,Tang K,Wang A,Jin Y
Tue Oct 06 00:00:00 EDT 2020
Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer.
Cell death & disease
Yang L,Zhou X,Sun J,Lei Q,Wang Q,Pan D,Ding M,Ding Y
Thu Sep 17 00:00:00 EDT 2020
Urinary ERdj3 and mesencephalic astrocyte-derived neutrophic factor identify endoplasmic reticulum stress in glomerular disease.
Laboratory investigation; a journal of technical methods and pathology
Tousson-Abouelazm N,Papillon J,Guillemette J,Cybulsky AV
Wed Jul 01 00:00:00 EDT 2020
MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6.
Laboratory investigation; a journal of technical methods and pathology
Yuan Q,Xu T,Chen Y,Qu W,Sun D,Liu X,Sun L
Sun Nov 01 00:00:00 EDT 2020
25-Hydroxycholesterol promotes vascular calcification via activation of endoplasmic reticulum stress.
European journal of pharmacology
Dong Q,Chen Y,Liu W,Liu X,Chen A,Yang X,Li Y,Wang S,Fu M,Ou JS,Lu L,Yan J
Wed Aug 05 00:00:00 EDT 2020
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Brain research bulletin
Liu Y,Wen D,Gao J,Xie B,Yu H,Shen Q,Zhang J,Jing W,Cong B,Ma C
Tue Sep 01 00:00:00 EDT 2020
Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice.
British journal of pharmacology
Gu M,Zhao P,Zhang S,Fan S,Yang L,Tong Q,Ji G,Huang C
Mon Apr 01 00:00:00 EDT 2019
Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice.
British journal of pharmacology
Gu M,Zhao P,Zhang S,Fan S,Yang L,Tong Q,Ji G,Huang C
Mon Apr 01 00:00:00 EDT 2019
Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice.
British journal of pharmacology
Gu M,Zhao P,Zhang S,Fan S,Yang L,Tong Q,Ji G,Huang C
Mon Apr 01 00:00:00 EDT 2019
IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages.
Immunology and cell biology
Ayaub EA,Tandon K,Padwal M,Imani J,Patel H,Dubey A,Mekhael O,Upagupta C,Ayoub A,Dvorkin-Gheva A,Murphy J,Kolb PS,Lhotak S,Dickhout JG,Austin RC,Kolb MRJ,Richards CD,Ask K
Fri Feb 01 00:00:00 EST 2019
IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages.
Immunology and cell biology
Ayaub EA,Tandon K,Padwal M,Imani J,Patel H,Dubey A,Mekhael O,Upagupta C,Ayoub A,Dvorkin-Gheva A,Murphy J,Kolb PS,Lhotak S,Dickhout JG,Austin RC,Kolb MRJ,Richards CD,Ask K
Fri Feb 01 00:00:00 EST 2019
Sigma-1 receptor protects against endoplasmic reticulum stress-mediated apoptosis in mice with cerebral ischemia/reperfusion injury.
Apoptosis : an international journal on programmed cell death
Zhao X,Zhu L,Liu D,Chi T,Ji X,Liu P,Yang X,Tian X,Zou L
Fri Feb 01 00:00:00 EST 2019
Sigma-1 receptor protects against endoplasmic reticulum stress-mediated apoptosis in mice with cerebral ischemia/reperfusion injury.
Apoptosis : an international journal on programmed cell death
Zhao X,Zhu L,Liu D,Chi T,Ji X,Liu P,Yang X,Tian X,Zou L
Fri Feb 01 00:00:00 EST 2019
Icariside II prevents hypertensive heart disease by alleviating endoplasmic reticulum stress via the PERK/ATF-4/CHOP signalling pathway in spontaneously hypertensive rats.
The Journal of pharmacy and pharmacology
Wu Y,Yue Y,Fu S,Li Y,Wu D,Lv J,Yang D
Fri Mar 01 00:00:00 EST 2019
Icariside II prevents hypertensive heart disease by alleviating endoplasmic reticulum stress via the PERK/ATF-4/CHOP signalling pathway in spontaneously hypertensive rats.
The Journal of pharmacy and pharmacology
Wu Y,Yue Y,Fu S,Li Y,Wu D,Lv J,Yang D
Fri Mar 01 00:00:00 EST 2019
20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway.
Journal of cellular biochemistry
Wang X,Xia HY,Qin HY,Kang XP,Hu HY,Zheng J,Jiang JY,Yao LA,Xu YW,Zhang T,Zhang XL
Mon Apr 01 00:00:00 EDT 2019
20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway.
Journal of cellular biochemistry
Wang X,Xia HY,Qin HY,Kang XP,Hu HY,Zheng J,Jiang JY,Yao LA,Xu YW,Zhang T,Zhang XL
Mon Apr 01 00:00:00 EDT 2019
Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons.
Neurochemistry international
Li S,Jiang Z,Chai W,Xu Y,Wang Y
Tue Jan 01 00:00:00 EST 2019
Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons.
Neurochemistry international
Li S,Jiang Z,Chai W,Xu Y,Wang Y
Tue Jan 01 00:00:00 EST 2019
Efficient RNA interference-based knockdown of mutant torsinA reveals reversibility of PERK-eIF2α pathway dysregulation in DYT1 transgenic rats in vivo.
Brain research
Beauvais G,Watson JL,Aguirre JA,Tecedor L,Ehrlich ME,Gonzalez-Alegre P
Fri Mar 01 00:00:00 EST 2019
Efficient RNA interference-based knockdown of mutant torsinA reveals reversibility of PERK-eIF2α pathway dysregulation in DYT1 transgenic rats in vivo.
Brain research
Beauvais G,Watson JL,Aguirre JA,Tecedor L,Ehrlich ME,Gonzalez-Alegre P
Fri Mar 01 00:00:00 EST 2019
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
In vitro cellular & developmental biology. Animal
Ullah O,Li Z,Ali I,Xu L,Liu H,Jin HZ,Fang YY,Jin QG,Fang N
Fri Feb 01 00:00:00 EST 2019
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
In vitro cellular & developmental biology. Animal
Ullah O,Li Z,Ali I,Xu L,Liu H,Jin HZ,Fang YY,Jin QG,Fang N
Fri Feb 01 00:00:00 EST 2019
Elevated ATF4 Expression in Odontogenic Keratocysts Epithelia: Potential Involvement in Tissue Hypoxia and Stromal M2 Macrophage Infiltration.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Zhong WQ,Li ZZ,Jiang H,Zou YP,Wang HT,Cai Y,Zhao Y,Zhao JH
Fri Nov 01 00:00:00 EDT 2019
Elevated ATF4 Expression in Odontogenic Keratocysts Epithelia: Potential Involvement in Tissue Hypoxia and Stromal M2 Macrophage Infiltration.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Zhong WQ,Li ZZ,Jiang H,Zou YP,Wang HT,Cai Y,Zhao Y,Zhao JH
Fri Nov 01 00:00:00 EDT 2019
Elevated ATF4 Expression in Odontogenic Keratocysts Epithelia: Potential Involvement in Tissue Hypoxia and Stromal M2 Macrophage Infiltration.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Zhong WQ,Li ZZ,Jiang H,Zou YP,Wang HT,Cai Y,Zhao Y,Zhao JH
Fri Nov 01 00:00:00 EDT 2019
Proteomic analysis of retinal pigment epithelium cells after exposure to UVA radiation.
BMC ophthalmology
Chen JL,Hung CT,Keller JJ,Lin HC,Wu YJ
Fri Aug 02 00:00:00 EDT 2019
Novel reprogramming of neutrophils modulates inflammation resolution during atherosclerosis.
Science advances
Geng S,Zhang Y,Lee C,Li L
Fri Feb 01 00:00:00 EST 2019
ER stress activation impairs the expression of circadian clock and clock-controlled genes in NIH3T3 cells via an ATF4-dependent mechanism.
Cellular signalling
Gao L,Chen H,Li C,Xiao Y,Yang D,Zhang M,Zhou D,Liu W,Wang A,Jin Y
Wed May 01 00:00:00 EDT 2019
Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells.
Cells
Tan Y,Jin Y,Wang Q,Huang J,Wu X,Ren Z
Fri Oct 11 00:00:00 EDT 2019
Porcine circovirus type 2 ORF5 protein induces endoplasmic reticulum stress and unfolded protein response in porcine alveolar macrophages.
Archives of virology
Ouyang Y,Xu L,Lv J,Hou Y,Fan Z,Xu P,Jiang Y,Wu M,Li R,Zhang Y,Guo K
Wed May 01 00:00:00 EDT 2019
Endoplasmic reticulum stress induces apoptosis of arginine vasopressin neurons in central diabetes insipidus via PI3K/Akt pathway.
CNS neuroscience & therapeutics
Zhou MF,Feng ZP,Ou YC,Peng JJ,Li K,Gong HD,Qiu BH,Liu YW,Wang YJ,Qi ST
Wed May 01 00:00:00 EDT 2019
Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.
Life sciences
Li F,Zhang Y,Lu X,Shi J,Gong Q
Tue Oct 01 00:00:00 EDT 2019
Japanese Encephalitis Virus Induces Apoptosis and Encephalitis by Activating the PERK Pathway.
Journal of virology
Wang Q,Xin X,Wang T,Wan J,Ou Y,Yang Z,Yu Q,Zhu L,Guo Y,Wu Y,Ding Z,Zhang Y,Pan Z,Tang Y,Li S,Kong L
Sun Sep 01 00:00:00 EDT 2019
Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity.
eLife
Kitakaze K,Taniuchi S,Kawano E,Hamada Y,Miyake M,Oyadomari M,Kojima H,Kosako H,Kuribara T,Yoshida S,Hosoya T,Oyadomari S
Tue Dec 17 00:00:00 EST 2019
Parkin-Dependent Mitophagy is Required for the Inhibition of ATF4 on NLRP3 Inflammasome Activation in Cerebral Ischemia-Reperfusion Injury in Rats.
Cells
He Q,Li Z,Meng C,Wu J,Zhao Y,Zhao J
Wed Aug 14 00:00:00 EDT 2019
Flaccidoxide-13-Acetate-Induced Apoptosis in Human Bladder Cancer Cells is through Activation of p38/JNK, Mitochondrial Dysfunction, and Endoplasmic Reticulum Stress Regulated Pathway.
Marine drugs
Wu YJ,Su TR,Dai GF,Su JH,Liu CI
Mon May 13 00:00:00 EDT 2019
Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer.
Oncogene
Pällmann N,Livgård M,Tesikova M,Zeynep Nenseth H,Akkus E,Sikkeland J,Jin Y,Koc D,Kuzu OF,Pradhan M,Danielsen HE,Kahraman N,Mokhlis HM,Ozpolat B,Banerjee PP,Uren A,Fazli L,Rennie PS,Jin Y,Saatcioglu F
Thu Aug 01 00:00:00 EDT 2019
KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.
World journal of gastrointestinal oncology
Li SS,Jiang WL,Xiao WQ,Li K,Zhang YF,Guo XY,Dai YQ,Zhao QY,Jiang MJ,Lu ZJ,Wan R
Thu Aug 15 00:00:00 EDT 2019
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis.
Cell
Ast T,Meisel JD,Patra S,Wang H,Grange RMH,Kim SH,Calvo SE,Orefice LL,Nagashima F,Ichinose F,Zapol WM,Ruvkun G,Barondeau DP,Mootha VK
Thu May 30 00:00:00 EDT 2019
Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells.
Oncogene
Zhu Y,Xie M,Meng Z,Leung LK,Chan FL,Hu X,Chi K,Liu C,Yao X
Mon Jul 01 00:00:00 EDT 2019
HHQ-4, a quinoline derivate, preferentially inhibits proliferation of glucose-deprived breast cancer cells as a GRP78 down-regulator.
Toxicology and applied pharmacology
Xiao X,Li S,Zhang X,Lu J,Wang W,Zhou S,Zhang J,Wang R,Li A
Sat Jun 15 00:00:00 EDT 2019
Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu J,Wu Q,Wang Z,Hong J,Chen R,Li B,Hu Z,Hu X,Zhang M
Sun Dec 01 00:00:00 EST 2019
mTOR-S6K1 pathway mediates cytoophidium assembly.
Journal of genetics and genomics = Yi chuan xue bao
Sun Z,Liu JL
Fri Feb 01 00:00:00 EST 2019
Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells.
Journal of ophthalmology
Wu S,Zhu X,Guo B,Zheng T,Ren J,Zeng W,Chen X,Ke M
Fri Apr 08 00:00:00 EDT 2022
Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells.
Journal of ophthalmology
Wu S,Zhu X,Guo B,Zheng T,Ren J,Zeng W,Chen X,Ke M
Fri Apr 08 00:00:00 EDT 2022
Nucleotide-binding oligomerization domain protein 2 attenuates ER stress-induced cell death in vascular smooth muscle cells.
BMB reports
Kwon MY,Hwang N,Lee SJ,Chung SW
Fri Nov 01 00:00:00 EDT 2019
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Cell metabolism
Luo H,Jiang M,Lian G,Liu Q,Shi M,Li TY,Song L,Ye J,He Y,Yao L,Zhang C,Lin ZZ,Zhang CS,Zhao TJ,Jia WP,Li P,Lin SY,Lin SC
Tue Apr 03 00:00:00 EDT 2018
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Cell metabolism
Luo H,Jiang M,Lian G,Liu Q,Shi M,Li TY,Song L,Ye J,He Y,Yao L,Zhang C,Lin ZZ,Zhang CS,Zhao TJ,Jia WP,Li P,Lin SY,Lin SC
Tue Apr 03 00:00:00 EDT 2018
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Autophagy
Sun P,Zhang S,Qin X,Chang X,Cui X,Li H,Zhang S,Gao H,Wang P,Zhang Z,Luo J,Li Z
Tue Feb 26 00:00:00 EST 2019
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Autophagy
Sun P,Zhang S,Qin X,Chang X,Cui X,Li H,Zhang S,Gao H,Wang P,Zhang Z,Luo J,Li Z
Tue Feb 26 00:00:00 EST 2019
Foot-and-mouth disease virus capsid protein VP2 activates the cellular EIF2S1-ATF4 pathway and induces autophagy via HSPB1.
Autophagy
Sun P,Zhang S,Qin X,Chang X,Cui X,Li H,Zhang S,Gao H,Wang P,Zhang Z,Luo J,Li Z
Tue Feb 26 00:00:00 EST 2019
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
The Science of the total environment
Li P,Liu L,Zhou G,Tian Z,Luo C,Xia T,Chen J,Niu Q,Dong L,Zhao Q,Wang A,Zhang S
Sat Dec 15 00:00:00 EST 2018
Perigestational exposure to low doses of PBDE-47 induces excessive ER stress, defective autophagy and the resultant apoptosis contributing to maternal thyroid toxicity.
The Science of the total environment
Li P,Liu L,Zhou G,Tian Z,Luo C,Xia T,Chen J,Niu Q,Dong L,Zhao Q,Wang A,Zhang S
Sat Dec 15 00:00:00 EST 2018
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Oxidative medicine and cellular longevity
Maryam A,Mehmood T,Yan Q,Li Y,Khan M,Ma T
Tue Sep 18 00:00:00 EDT 2018
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Oxidative medicine and cellular longevity
Maryam A,Mehmood T,Yan Q,Li Y,Khan M,Ma T
Tue Sep 18 00:00:00 EDT 2018
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Oxidative medicine and cellular longevity
Jia Y,Li Z,Feng Y,Cui R,Dong Y,Zhang X,Xiang X,Qu K,Liu C,Zhang J
Tue Jan 22 00:00:00 EST 2019
Methane-Rich Saline Ameliorates Sepsis-Induced Acute Kidney Injury through Anti-Inflammation, Antioxidative, and Antiapoptosis Effects by Regulating Endoplasmic Reticulum Stress.
Oxidative medicine and cellular longevity
Jia Y,Li Z,Feng Y,Cui R,Dong Y,Zhang X,Xiang X,Qu K,Liu C,Zhang J
Tue Jan 22 00:00:00 EST 2019
eIF2β, a subunit of translation-initiation factor EIF2, is a potential therapeutic target for non-small cell lung cancer.
Cancer science
Tanaka I,Sato M,Kato T,Goto D,Kakumu T,Miyazawa A,Yogo N,Hase T,Morise M,Sekido Y,Girard L,Minna JD,Byers LA,Heymach JV,Coombes KR,Kondo M,Hasegawa Y
Fri Jun 01 00:00:00 EDT 2018
eIF2β, a subunit of translation-initiation factor EIF2, is a potential therapeutic target for non-small cell lung cancer.
Cancer science
Tanaka I,Sato M,Kato T,Goto D,Kakumu T,Miyazawa A,Yogo N,Hase T,Morise M,Sekido Y,Girard L,Minna JD,Byers LA,Heymach JV,Coombes KR,Kondo M,Hasegawa Y
Fri Jun 01 00:00:00 EDT 2018
TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.
Journal of molecular and cellular cardiology
Li Z,Meng Z,Lu J,Chen FM,Wong WT,Tse G,Zheng C,Keung W,Tse K,Li RA,Jiang L,Yao X
Sun Jul 01 00:00:00 EDT 2018
TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.
Journal of molecular and cellular cardiology
Li Z,Meng Z,Lu J,Chen FM,Wong WT,Tse G,Zheng C,Keung W,Tse K,Li RA,Jiang L,Yao X
Sun Jul 01 00:00:00 EDT 2018
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
International immunopharmacology
Wang D,Lao L,Pang X,Qiao Q,Pang L,Feng Z,Bai F,Sun X,Lin X,Wei J
Sat Dec 01 00:00:00 EST 2018
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
International immunopharmacology
Wang D,Lao L,Pang X,Qiao Q,Pang L,Feng Z,Bai F,Sun X,Lin X,Wei J
Sat Dec 01 00:00:00 EST 2018
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
European journal of nutrition
Pan S,Jia Y,Yang X,Cai D,Liu Z,Song H,Zhao R
Sun Apr 01 00:00:00 EDT 2018
Amino acid starvation-induced autophagy is involved in reduced subcutaneous fat deposition in weaning piglets derived from sows fed low-protein diet during gestation and lactation : Autophagy is involved in reduced fat deposition in maternal low-protein piglets.
European journal of nutrition
Pan S,Jia Y,Yang X,Cai D,Liu Z,Song H,Zhao R
Sun Apr 01 00:00:00 EDT 2018
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Journal of Cancer
Duan YM,Jin Y,Guo ML,Duan LX,Wang JG
Wed Sep 30 00:00:00 EDT 2020
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Journal of Cancer
Duan YM,Jin Y,Guo ML,Duan LX,Wang JG
Wed Sep 30 00:00:00 EDT 2020
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Experimental cell research
Geng W,Qin F,Ren J,Xiao S,Wang A
Wed Aug 15 00:00:00 EDT 2018
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Experimental cell research
Geng W,Qin F,Ren J,Xiao S,Wang A
Wed Aug 15 00:00:00 EDT 2018
Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress.
Microvascular research
Wang X,Han X,Li M,Han Y,Zhang Y,Zhao S,Li Y
Sat Sep 01 00:00:00 EDT 2018
Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress.
Microvascular research
Wang X,Han X,Li M,Han Y,Zhang Y,Zhao S,Li Y
Sat Sep 01 00:00:00 EDT 2018
Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain.
Neuroscience
Beauvais G,Rodriguez-Losada N,Ying L,Zakirova Z,Watson JL,Readhead B,Gadue P,French DL,Ehrlich ME,Gonzalez-Alegre P
Sat Feb 10 00:00:00 EST 2018
Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain.
Neuroscience
Beauvais G,Rodriguez-Losada N,Ying L,Zakirova Z,Watson JL,Readhead B,Gadue P,French DL,Ehrlich ME,Gonzalez-Alegre P
Sat Feb 10 00:00:00 EST 2018
ATF4 Involvement in TLR4 and LOX-1-Induced Host Inflammatory Response to Aspergillus fumigatus Keratitis.
Journal of ophthalmology
Zhang S,Meng P,Liu G,Liu K,Che C
Thu Mar 31 00:00:00 EDT 2022
ATF4 Involvement in TLR4 and LOX-1-Induced Host Inflammatory Response to Aspergillus fumigatus Keratitis.
Journal of ophthalmology
Zhang S,Meng P,Liu G,Liu K,Che C
Thu Mar 31 00:00:00 EDT 2022
ATF4 Involvement in TLR4 and LOX-1-Induced Host Inflammatory Response to Aspergillus fumigatus Keratitis.
Journal of ophthalmology
Zhang S,Meng P,Liu G,Liu K,Che C
Thu Mar 31 00:00:00 EDT 2022
Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.
Cell death & disease
Krishnamoorthy J,Tenkerian C,Gupta J,Ghaddar N,Wang S,Darini C,Staschke KA,Ghosh A,Gandin V,Topisirovic I,Kristof AS,Hatzoglou M,Simos G,Koromilas AE
Thu Feb 15 00:00:00 EST 2018
Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells.
Cell death & disease
Krishnamoorthy J,Tenkerian C,Gupta J,Ghaddar N,Wang S,Darini C,Staschke KA,Ghosh A,Gandin V,Topisirovic I,Kristof AS,Hatzoglou M,Simos G,Koromilas AE
Thu Feb 15 00:00:00 EST 2018
Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase.
Cell reports
Lin WC,Chakraborty A,Huang SC,Wang PY,Hsieh YJ,Chien KY,Lee YH,Chang CC,Tang HY,Lin YT,Tung CS,Luo JD,Chen TW,Lin TY,Cheng ML,Chen YT,Yeh CT,Liu JL,Sung LY,Shiao MS,Yu JS,Chang YS,Pai LM
Tue Sep 04 00:00:00 EDT 2018
Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase.
Cell reports
Lin WC,Chakraborty A,Huang SC,Wang PY,Hsieh YJ,Chien KY,Lee YH,Chang CC,Tang HY,Lin YT,Tung CS,Luo JD,Chen TW,Lin TY,Cheng ML,Chen YT,Yeh CT,Liu JL,Sung LY,Shiao MS,Yu JS,Chang YS,Pai LM
Tue Sep 04 00:00:00 EDT 2018
Defective interplay between mTORC1 activity and endoplasmic reticulum stress-unfolded protein response in uremic vascular calcification.
American journal of physiology. Renal physiology
Panda DK,Bai X,Sabbagh Y,Zhang Y,Zaun HC,Karellis A,Koromilas AE,Lipman ML,Karaplis AC
Fri Jun 01 00:00:00 EDT 2018
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Marine drugs
Tsai TC,Lai KH,Su JH,Wu YJ,Sheu JH
Mon Mar 26 00:00:00 EDT 2018
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Marine drugs
Tsai TC,Lai KH,Su JH,Wu YJ,Sheu JH
Mon Mar 26 00:00:00 EDT 2018
Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein.
JCI insight
Burman A,Kropski JA,Calvi CL,Serezani AP,Pascoalino BD,Han W,Sherrill T,Gleaves L,Lawson WE,Young LR,Blackwell TS,Tanjore H
Thu Aug 23 00:00:00 EDT 2018
Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein.
JCI insight
Burman A,Kropski JA,Calvi CL,Serezani AP,Pascoalino BD,Han W,Sherrill T,Gleaves L,Lawson WE,Young LR,Blackwell TS,Tanjore H
Thu Aug 23 00:00:00 EDT 2018
Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione Biosynthesis.
International journal of molecular sciences
Wang SF,Wung CH,Chen MS,Chen CF,Yin PH,Yeh TS,Chang YL,Chou YC,Hung HH,Lee HC
Mon Oct 29 00:00:00 EDT 2018
Activated Integrated Stress Response Induced by Salubrinal Promotes Cisplatin Resistance in Human Gastric Cancer Cells via Enhanced xCT Expression and Glutathione Biosynthesis.
International journal of molecular sciences
Wang SF,Wung CH,Chen MS,Chen CF,Yin PH,Yeh TS,Chang YL,Chou YC,Hung HH,Lee HC
Mon Oct 29 00:00:00 EDT 2018
18β-Glycyrrhetinic-acid-mediated unfolded protein response induces autophagy and apoptosis in hepatocellular carcinoma.
Scientific reports
Chen J,Zhang ZQ,Song J,Liu QM,Wang C,Huang Z,Chu L,Liang HF,Zhang BX,Chen XP
Tue Jun 19 00:00:00 EDT 2018
18β-Glycyrrhetinic-acid-mediated unfolded protein response induces autophagy and apoptosis in hepatocellular carcinoma.
Scientific reports
Chen J,Zhang ZQ,Song J,Liu QM,Wang C,Huang Z,Chu L,Liang HF,Zhang BX,Chen XP
Tue Jun 19 00:00:00 EDT 2018
DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy.
Developmental cell
Nguyen TB,Louie SM,Daniele JR,Tran Q,Dillin A,Zoncu R,Nomura DK,Olzmann JA
Mon Jul 10 00:00:00 EDT 2017
DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy.
Developmental cell
Nguyen TB,Louie SM,Daniele JR,Tran Q,Dillin A,Zoncu R,Nomura DK,Olzmann JA
Mon Jul 10 00:00:00 EDT 2017
When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157.
Cell death and differentiation
Rojas-Rivera D,Delvaeye T,Roelandt R,Nerinckx W,Augustyns K,Vandenabeele P,Bertrand MJM
Thu Jun 01 00:00:00 EDT 2017
When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157.
Cell death and differentiation
Rojas-Rivera D,Delvaeye T,Roelandt R,Nerinckx W,Augustyns K,Vandenabeele P,Bertrand MJM
Thu Jun 01 00:00:00 EDT 2017
Hyperglycemia Aggravates Hepatic Ischemia and Reperfusion Injury by Inhibiting Liver-Resident Macrophage M2 Polarization via C/EBP Homologous Protein-Mediated Endoplasmic Reticulum Stress.
Frontiers in immunology
Rao Z,Sun J,Pan X,Chen Z,Sun H,Zhang P,Gao M,Ding Z,Liu C
Sun Apr 10 00:00:00 EDT 2022
Hyperglycemia Aggravates Hepatic Ischemia and Reperfusion Injury by Inhibiting Liver-Resident Macrophage M2 Polarization via C/EBP Homologous Protein-Mediated Endoplasmic Reticulum Stress.
Frontiers in immunology
Rao Z,Sun J,Pan X,Chen Z,Sun H,Zhang P,Gao M,Ding Z,Liu C
Sun Apr 10 00:00:00 EDT 2022
Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway.
Free radical biology & medicine
Kim HJ,Joe Y,Kim SK,Park SU,Park J,Chen Y,Kim J,Ryu J,Cho GJ,Surh YJ,Ryter SW,Kim UH,Chung HT
Fri Sep 01 00:00:00 EDT 2017
Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway.
Free radical biology & medicine
Kim HJ,Joe Y,Kim SK,Park SU,Park J,Chen Y,Kim J,Ryu J,Cho GJ,Surh YJ,Ryter SW,Kim UH,Chung HT
Fri Sep 01 00:00:00 EDT 2017
Discovery of a Benzamide Derivative That Protects Pancreatic β-Cells against Endoplasmic Reticulum Stress.
Journal of medicinal chemistry
Duan H,Li Y,Arora D,Xu D,Lim HY,Wang W
Thu Jul 27 00:00:00 EDT 2017
Discovery of a Benzamide Derivative That Protects Pancreatic β-Cells against Endoplasmic Reticulum Stress.
Journal of medicinal chemistry
Duan H,Li Y,Arora D,Xu D,Lim HY,Wang W
Thu Jul 27 00:00:00 EDT 2017
β-elemene regulates endoplasmic reticulum stress to induce the apoptosis of NSCLC cells through PERK/IRE1α/ATF6 pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Y,Jiang ZY,Zhou YL,Qiu HH,Wang G,Luo Y,Liu JB,Liu XW,Bu WQ,Song J,Cui L,Jia XB,Feng L
Fri Sep 01 00:00:00 EDT 2017
β-elemene regulates endoplasmic reticulum stress to induce the apoptosis of NSCLC cells through PERK/IRE1α/ATF6 pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Liu Y,Jiang ZY,Zhou YL,Qiu HH,Wang G,Luo Y,Liu JB,Liu XW,Bu WQ,Song J,Cui L,Jia XB,Feng L
Fri Sep 01 00:00:00 EDT 2017
TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity.
Oxidative medicine and cellular longevity
Wang Y,Gu YH,Liu M,Bai Y,Liang LY,Wang HL
Mon Mar 27 00:00:00 EDT 2017
TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity.
Oxidative medicine and cellular longevity
Wang Y,Gu YH,Liu M,Bai Y,Liang LY,Wang HL
Mon Mar 27 00:00:00 EDT 2017
Endoplasmic reticulum stress and apoptosis via PERK-eIF2α-CHOP signaling in the methamphetamine-induced chronic pulmonary injury.
Environmental toxicology and pharmacology
Gu YH,Wang Y,Bai Y,Liu M,Wang HL
Sun Jan 01 00:00:00 EST 2017
Endoplasmic reticulum stress and apoptosis via PERK-eIF2α-CHOP signaling in the methamphetamine-induced chronic pulmonary injury.
Environmental toxicology and pharmacology
Gu YH,Wang Y,Bai Y,Liu M,Wang HL
Sun Jan 01 00:00:00 EST 2017
Endoplasmic reticulum stress and apoptosis via PERK-eIF2α-CHOP signaling in the methamphetamine-induced chronic pulmonary injury.
Environmental toxicology and pharmacology
Gu YH,Wang Y,Bai Y,Liu M,Wang HL
Sun Jan 01 00:00:00 EST 2017
The novel autophagy inhibitor elaiophylin exerts antitumor activity against multiple myeloma with mutant TP53 in part through endoplasmic reticulum stress-induced apoptosis.
Cancer biology & therapy
Wang G,Zhou P,Chen X,Zhao L,Tan J,Yang Y,Fang Y,Zhou J
Thu Aug 03 00:00:00 EDT 2017
The novel autophagy inhibitor elaiophylin exerts antitumor activity against multiple myeloma with mutant TP53 in part through endoplasmic reticulum stress-induced apoptosis.
Cancer biology & therapy
Wang G,Zhou P,Chen X,Zhao L,Tan J,Yang Y,Fang Y,Zhou J
Thu Aug 03 00:00:00 EDT 2017
Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR.
Cellular signalling
Yin Y,Chen C,Chen J,Zhan R,Zhang Q,Xu X,Li D,Li M
Sat Jul 01 00:00:00 EDT 2017
Cell surface GRP78 facilitates hepatoma cells proliferation and migration by activating IGF-IR.
Cellular signalling
Yin Y,Chen C,Chen J,Zhan R,Zhang Q,Xu X,Li D,Li M
Sat Jul 01 00:00:00 EDT 2017
Association of ATF4 Expression With Tissue Hypoxia and M2 Macrophage Infiltration in Infantile Hemangioma.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Xia HF,Zhu JY,Wang JN,Ren JG,Cai Y,Wang FQ,Zhang W,Chen G,Zhao YF,Zhao JH
Mon May 01 00:00:00 EDT 2017
Association of ATF4 Expression With Tissue Hypoxia and M2 Macrophage Infiltration in Infantile Hemangioma.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Xia HF,Zhu JY,Wang JN,Ren JG,Cai Y,Wang FQ,Zhang W,Chen G,Zhao YF,Zhao JH
Mon May 01 00:00:00 EDT 2017
Association of ATF4 Expression With Tissue Hypoxia and M2 Macrophage Infiltration in Infantile Hemangioma.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Xia HF,Zhu JY,Wang JN,Ren JG,Cai Y,Wang FQ,Zhang W,Chen G,Zhao YF,Zhao JH
Mon May 01 00:00:00 EDT 2017
Stress granules assembly affects detection of mRNA in living cells by the NanoFlares; an important aspect of the technology.
Biochimica et biophysica acta. General subjects
Wolczyk M,Podszywalow-Bartnicka P,Bugajski L,Piwocka K
Mon May 01 00:00:00 EDT 2017
Stress granules assembly affects detection of mRNA in living cells by the NanoFlares; an important aspect of the technology.
Biochimica et biophysica acta. General subjects
Wolczyk M,Podszywalow-Bartnicka P,Bugajski L,Piwocka K
Mon May 01 00:00:00 EDT 2017
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
Biology open
Liu J,Li M,Gong J,Han P,Wang Y,Li D,Tian D,Liao J
Sun Jan 15 00:00:00 EST 2017
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
Biology open
Liu J,Li M,Gong J,Han P,Wang Y,Li D,Tian D,Liao J
Sun Jan 15 00:00:00 EST 2017
eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet.
Nutrition & metabolism
Choi WG,Han J,Kim JH,Kim MJ,Park JW,Song B,Cha HJ,Choi HS,Chung HT,Lee IK,Park TS,Hatzoglou M,Choi HS,Yoo HJ,Kaufman RJ,Back SH
Thu Oct 01 00:00:00 EDT 2020
eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet.
Nutrition & metabolism
Choi WG,Han J,Kim JH,Kim MJ,Park JW,Song B,Cha HJ,Choi HS,Chung HT,Lee IK,Park TS,Hatzoglou M,Choi HS,Yoo HJ,Kaufman RJ,Back SH
Thu Oct 01 00:00:00 EDT 2020
Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Cell & bioscience
Sun W,Yang J,Zhang Y,Xi Y,Wen X,Yuan D,Wang Y,Wei C,Wang R,Wu L,Li H,Xu C
Fri Mar 11 00:00:00 EST 2022
Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Cell & bioscience
Sun W,Yang J,Zhang Y,Xi Y,Wen X,Yuan D,Wang Y,Wei C,Wang R,Wu L,Li H,Xu C
Fri Mar 11 00:00:00 EST 2022
A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure.
Nature communications
Yao Y,Lu Q,Hu Z,Yu Y,Chen Q,Wang QK
Tue Jul 25 00:00:00 EDT 2017
A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure.
Nature communications
Yao Y,Lu Q,Hu Z,Yu Y,Chen Q,Wang QK
Tue Jul 25 00:00:00 EDT 2017
Transthyretin Exerts Pro-Apoptotic Effects in Human Retinal Microvascular Endothelial Cells Through a GRP78-Dependent Pathway in Diabetic Retinopathy.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Shao J,Yin Y,Yin X,Ji L,Xin Y,Zou J,Yao Y
Tue Oct 31 00:00:00 EDT 2017
Transthyretin Exerts Pro-Apoptotic Effects in Human Retinal Microvascular Endothelial Cells Through a GRP78-Dependent Pathway in Diabetic Retinopathy.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Shao J,Yin Y,Yin X,Ji L,Xin Y,Zou J,Yao Y
Tue Oct 31 00:00:00 EDT 2017
AvidinOX-anchored biotinylated trastuzumab and pertuzumab induce down-modulation of ErbB2 and tumor cell death at concentrations order of magnitude lower than not-anchored antibodies.
Oncotarget
Milazzo FM,Anastasi AM,Chiapparino C,Rosi A,Leoni B,Vesci L,Petronzelli F,De Santis R
Tue Apr 04 00:00:00 EDT 2017
AvidinOX-anchored biotinylated trastuzumab and pertuzumab induce down-modulation of ErbB2 and tumor cell death at concentrations order of magnitude lower than not-anchored antibodies.
Oncotarget
Milazzo FM,Anastasi AM,Chiapparino C,Rosi A,Leoni B,Vesci L,Petronzelli F,De Santis R
Tue Apr 04 00:00:00 EDT 2017
Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress.
Scientific reports
Maryam A,Mehmood T,Zhang H,Li Y,Khan M,Ma T
Mon Jul 24 00:00:00 EDT 2017
Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress.
Scientific reports
Maryam A,Mehmood T,Zhang H,Li Y,Khan M,Ma T
Mon Jul 24 00:00:00 EDT 2017
Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: Roles of PERK/eIF2α signaling pathway.
Brain, behavior, and immunity
Gao H,Yan P,Zhang S,Nie S,Huang F,Han H,Deng Q,Huang Q,Yang W,Wu H,Yao P,Ye K,Xu J,Liu L
Sat Oct 01 00:00:00 EDT 2016
Chronic alpha-linolenic acid treatment alleviates age-associated neuropathology: Roles of PERK/eIF2α signaling pathway.
Brain, behavior, and immunity
Gao H,Yan P,Zhang S,Nie S,Huang F,Han H,Deng Q,Huang Q,Yang W,Wu H,Yao P,Ye K,Xu J,Liu L
Sat Oct 01 00:00:00 EDT 2016
Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic β-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress.
Journal of medicinal chemistry
Duan H,Lee JW,Moon SW,Arora D,Li Y,Lim HY,Wang W
Thu Sep 08 00:00:00 EDT 2016
Discovery, Synthesis, and Evaluation of 2,4-Diaminoquinazolines as a Novel Class of Pancreatic β-Cell-Protective Agents against Endoplasmic Reticulum (ER) Stress.
Journal of medicinal chemistry
Duan H,Lee JW,Moon SW,Arora D,Li Y,Lim HY,Wang W
Thu Sep 08 00:00:00 EDT 2016
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu H,Wang C,Jin Y,Meng Q,Liu Q,Liu K,Sun H
Sun May 01 00:00:00 EDT 2016
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Hu H,Wang C,Jin Y,Meng Q,Liu Q,Liu K,Sun H
Sun May 01 00:00:00 EDT 2016
Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Beauvais G,Bode NM,Watson JL,Wen H,Glenn KA,Kawano H,Harata NC,Ehrlich ME,Gonzalez-Alegre P
Wed Oct 05 00:00:00 EDT 2016
Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Beauvais G,Bode NM,Watson JL,Wen H,Glenn KA,Kawano H,Harata NC,Ehrlich ME,Gonzalez-Alegre P
Wed Oct 05 00:00:00 EDT 2016
EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells.
American journal of cancer research
Hsieh YY,Lo HL,Yang PM
Tue Sep 20 00:00:00 EDT 2016
EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells.
American journal of cancer research
Hsieh YY,Lo HL,Yang PM
Tue Sep 20 00:00:00 EDT 2016
Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response.
Molecular and cellular biology
Reid DW,Tay AS,Sundaram JR,Lee IC,Chen Q,George SE,Nicchitta CV,Shenolikar S
Fri Jul 01 00:00:00 EDT 2016
Complementary Roles of GADD34- and CReP-Containing Eukaryotic Initiation Factor 2α Phosphatases during the Unfolded Protein Response.
Molecular and cellular biology
Reid DW,Tay AS,Sundaram JR,Lee IC,Chen Q,George SE,Nicchitta CV,Shenolikar S
Fri Jul 01 00:00:00 EDT 2016
Glucosamine induces REDD1 to suppress insulin action in retinal Müller cells.
Cellular signalling
Moore JA,Miller WP,Dennis MD
Sun May 01 00:00:00 EDT 2016
Glucosamine induces REDD1 to suppress insulin action in retinal Müller cells.
Cellular signalling
Moore JA,Miller WP,Dennis MD
Sun May 01 00:00:00 EDT 2016
N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells.
ACS chemical biology
Thinon E,Morales-Sanfrutos J,Mann DJ,Tate EW
Fri Aug 19 00:00:00 EDT 2016
N-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells.
ACS chemical biology
Thinon E,Morales-Sanfrutos J,Mann DJ,Tate EW
Fri Aug 19 00:00:00 EDT 2016
TBL2 Associates With ATF4 mRNA Via Its WD40 Domain and Regulates Its Translation During ER Stress.
Journal of cellular biochemistry
Tsukumo Y,Tsukahara S,Furuno A,Iemura S,Natsume T,Tomida A
Mon Feb 01 00:00:00 EST 2016
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Toxicology in vitro : an international journal published in association with BIBRA
Zhang W,Chen L,Shen Y,Xu J
Sat Oct 01 00:00:00 EDT 2016
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Toxicology in vitro : an international journal published in association with BIBRA
Zhang W,Chen L,Shen Y,Xu J
Sat Oct 01 00:00:00 EDT 2016
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Toxicology in vitro : an international journal published in association with BIBRA
Zhang W,Chen L,Shen Y,Xu J
Sat Oct 01 00:00:00 EDT 2016
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Toxicology in vitro : an international journal published in association with BIBRA
Zhang W,Chen L,Shen Y,Xu J
Sat Oct 01 00:00:00 EDT 2016
Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice.
Biochemical and biophysical research communications
Fujita Y,Makishima M,Bhawal UK
Fri Jan 15 00:00:00 EST 2016
Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice.
Biochemical and biophysical research communications
Fujita Y,Makishima M,Bhawal UK
Fri Jan 15 00:00:00 EST 2016
Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice.
Biochemical and biophysical research communications
Fujita Y,Makishima M,Bhawal UK
Fri Jan 15 00:00:00 EST 2016
Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice.
Biochemical and biophysical research communications
Fujita Y,Makishima M,Bhawal UK
Fri Jan 15 00:00:00 EST 2016
Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta.
PLoS genetics
Cabral WA,Ishikawa M,Garten M,Makareeva EN,Sargent BM,Weis M,Barnes AM,Webb EA,Shaw NJ,Ala-Kokko L,Lacbawan FL,Högler W,Leikin S,Blank PS,Zimmerberg J,Eyre DR,Yamada Y,Marini JC
Fri Jul 01 00:00:00 EDT 2016
Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta.
PLoS genetics
Cabral WA,Ishikawa M,Garten M,Makareeva EN,Sargent BM,Weis M,Barnes AM,Webb EA,Shaw NJ,Ala-Kokko L,Lacbawan FL,Högler W,Leikin S,Blank PS,Zimmerberg J,Eyre DR,Yamada Y,Marini JC
Fri Jul 01 00:00:00 EDT 2016
The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress.
Oncotarget
Rajesh K,Krishnamoorthy J,Gupta J,Kazimierczak U,Papadakis AI,Deng Z,Wang S,Kuninaka S,Koromilas AE
Tue Aug 09 00:00:00 EDT 2016
The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress.
Oncotarget
Rajesh K,Krishnamoorthy J,Gupta J,Kazimierczak U,Papadakis AI,Deng Z,Wang S,Kuninaka S,Koromilas AE
Tue Aug 09 00:00:00 EDT 2016
Increased phosphorylation of eIF2α in chronic myeloid leukemia cells stimulates secretion of matrix modifying enzymes.
Oncotarget
Podszywalow-Bartnicka P,Cmoch A,Wolczyk M,Bugajski L,Tkaczyk M,Dadlez M,Nieborowska-Skorska M,Koromilas AE,Skorski T,Piwocka K
Tue Nov 29 00:00:00 EST 2016
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
International journal of molecular sciences
Lin JJ,Wang RY,Chen JC,Chiu CC,Liao MH,Wu YJ
Thu Oct 27 00:00:00 EDT 2016
Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction.
International journal of molecular sciences
Lin JJ,Wang RY,Chen JC,Chiu CC,Liao MH,Wu YJ
Thu Oct 27 00:00:00 EDT 2016
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.
Nature communications
Krall AS,Xu S,Graeber TG,Braas D,Christofk HR
Fri Apr 29 00:00:00 EDT 2016
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor.
Nature communications
Krall AS,Xu S,Graeber TG,Braas D,Christofk HR
Fri Apr 29 00:00:00 EDT 2016
Mitochondrial dysfunction enhances cisplatin resistance in human gastric cancer cells via the ROS-activated GCN2-eIF2α-ATF4-xCT pathway.
Oncotarget
Wang SF,Chen MS,Chou YC,Ueng YF,Yin PH,Yeh TS,Lee HC
Tue Nov 08 00:00:00 EST 2016
The Dichotomy of Endoplasmic Reticulum Stress Response in Liver Ischemia-Reperfusion Injury.
Transplantation
Zhou H,Zhu J,Yue S,Lu L,Busuttil RW,Kupiec-Weglinski JW,Wang X,Zhai Y
Mon Feb 01 00:00:00 EST 2016
STAMP2 increases oxidative stress and is critical for prostate cancer.
EMBO molecular medicine
Jin Y,Wang L,Qu S,Sheng X,Kristian A,Mælandsmo GM,Pällmann N,Yuca E,Tekedereli I,Gorgulu K,Alpay N,Sood A,Lopez-Berestein G,Fazli L,Rennie P,Risberg B,Wæhre H,Danielsen HE,Ozpolat B,Saatcioglu F
Sun Mar 01 00:00:00 EST 2015
STAMP2 increases oxidative stress and is critical for prostate cancer.
EMBO molecular medicine
Jin Y,Wang L,Qu S,Sheng X,Kristian A,Mælandsmo GM,Pällmann N,Yuca E,Tekedereli I,Gorgulu K,Alpay N,Sood A,Lopez-Berestein G,Fazli L,Rennie P,Risberg B,Wæhre H,Danielsen HE,Ozpolat B,Saatcioglu F
Sun Mar 01 00:00:00 EST 2015
Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death.
Oncogene
Yang CS,Matsuura K,Huang NJ,Robeson AC,Huang B,Zhang L,Kornbluth S
Mon Jun 01 00:00:00 EDT 2015
Fatty acid synthase inhibition engages a novel caspase-2 regulatory mechanism to induce ovarian cancer cell death.
Oncogene
Yang CS,Matsuura K,Huang NJ,Robeson AC,Huang B,Zhang L,Kornbluth S
Mon Jun 01 00:00:00 EDT 2015
Translation of 5' leaders is pervasive in genes resistant to eIF2 repression.
eLife
Andreev DE,O'Connor PB,Fahey C,Kenny EM,Terenin IM,Dmitriev SE,Cormican P,Morris DW,Shatsky IN,Baranov PV
Mon Jan 26 00:00:00 EST 2015
Translation of 5' leaders is pervasive in genes resistant to eIF2 repression.
eLife
Andreev DE,O'Connor PB,Fahey C,Kenny EM,Terenin IM,Dmitriev SE,Cormican P,Morris DW,Shatsky IN,Baranov PV
Mon Jan 26 00:00:00 EST 2015
mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under Stress.
Molecular cancer research : MCR
Tenkerian C,Krishnamoorthy J,Mounir Z,Kazimierczak U,Khoutorsky A,Staschke KA,Kristof AS,Wang S,Hatzoglou M,Koromilas AE
Thu Oct 01 00:00:00 EDT 2015
mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under Stress.
Molecular cancer research : MCR
Tenkerian C,Krishnamoorthy J,Mounir Z,Kazimierczak U,Khoutorsky A,Staschke KA,Kristof AS,Wang S,Hatzoglou M,Koromilas AE
Thu Oct 01 00:00:00 EDT 2015
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Chemical research in toxicology
Xu D,Su C,Song X,Shi Q,Fu J,Hu L,Xia X,Song E,Song Y
Mon Jun 15 00:00:00 EDT 2015
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Chemical research in toxicology
Xu D,Su C,Song X,Shi Q,Fu J,Hu L,Xia X,Song E,Song Y
Mon Jun 15 00:00:00 EDT 2015
Identification of 5-nitrofuran-2-amide derivatives that induce apoptosis in triple negative breast cancer cells by activating C/EBP-homologous protein expression.
Bioorganic & medicinal chemistry
Duan H,Li Y,Lim HY,Wang W
Sat Aug 01 00:00:00 EDT 2015
Identification of 5-nitrofuran-2-amide derivatives that induce apoptosis in triple negative breast cancer cells by activating C/EBP-homologous protein expression.
Bioorganic & medicinal chemistry
Duan H,Li Y,Lim HY,Wang W
Sat Aug 01 00:00:00 EDT 2015
The novel β2-selective proteasome inhibitor LU-102 decreases phosphorylation of I kappa B and induces highly synergistic cytotoxicity in combination with ibrutinib in multiple myeloma cells.
Cancer chemotherapy and pharmacology
Kraus J,Kraus M,Liu N,Besse L,Bader J,Geurink PP,de Bruin G,Kisselev AF,Overkleeft H,Driessen C
Sat Aug 01 00:00:00 EDT 2015
The novel β2-selective proteasome inhibitor LU-102 decreases phosphorylation of I kappa B and induces highly synergistic cytotoxicity in combination with ibrutinib in multiple myeloma cells.
Cancer chemotherapy and pharmacology
Kraus J,Kraus M,Liu N,Besse L,Bader J,Geurink PP,de Bruin G,Kisselev AF,Overkleeft H,Driessen C
Sat Aug 01 00:00:00 EDT 2015
Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress.
Cell death & disease
Rajesh K,Krishnamoorthy J,Kazimierczak U,Tenkerian C,Papadakis AI,Wang S,Huang S,Koromilas AE
Thu Jan 15 00:00:00 EST 2015
Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress.
Cell death & disease
Rajesh K,Krishnamoorthy J,Kazimierczak U,Tenkerian C,Papadakis AI,Wang S,Huang S,Koromilas AE
Thu Jan 15 00:00:00 EST 2015
PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.
Neurobiology of aging
Devi L,Ohno M
Wed Oct 01 00:00:00 EDT 2014
PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.
Neurobiology of aging
Devi L,Ohno M
Wed Oct 01 00:00:00 EDT 2014
Ionizing radiation activates PERK/eIF2α/ATF4 signaling via ER stress-independent pathway in human vascular endothelial cells.
International journal of radiation biology
Kim EJ,Lee YJ,Kang S,Lim YB
Tue Apr 01 00:00:00 EDT 2014
Ionizing radiation activates PERK/eIF2α/ATF4 signaling via ER stress-independent pathway in human vascular endothelial cells.
International journal of radiation biology
Kim EJ,Lee YJ,Kang S,Lim YB
Tue Apr 01 00:00:00 EDT 2014
HKH40A downregulates GRP78/BiP expression in cancer cells.
Cell death & disease
Kosakowska-Cholody T,Lin J,Srideshikan SM,Scheffer L,Tarasova NI,Acharya JK
Thu May 22 00:00:00 EDT 2014
HKH40A downregulates GRP78/BiP expression in cancer cells.
Cell death & disease
Kosakowska-Cholody T,Lin J,Srideshikan SM,Scheffer L,Tarasova NI,Acharya JK
Thu May 22 00:00:00 EDT 2014
Downregulation of BRCA1 protein in BCR-ABL1 leukemia cells depends on stress-triggered TIAR-mediated suppression of translation.
Cell cycle (Georgetown, Tex.)
Podszywalow-Bartnicka P,Wolczyk M,Kusio-Kobialka M,Wolanin K,Skowronek K,Nieborowska-Skorska M,Dasgupta Y,Skorski T,Piwocka K
Thu Sep 10 00:00:00 EDT 2015
Downregulation of BRCA1 protein in BCR-ABL1 leukemia cells depends on stress-triggered TIAR-mediated suppression of translation.
Cell cycle (Georgetown, Tex.)
Podszywalow-Bartnicka P,Wolczyk M,Kusio-Kobialka M,Wolanin K,Skowronek K,Nieborowska-Skorska M,Dasgupta Y,Skorski T,Piwocka K
Thu Sep 10 00:00:00 EDT 2015
TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.
PloS one
Tsukumo Y,Tsukahara S,Furuno A,Iemura S,Natsume T,Tomida A
Mon Jul 06 00:00:00 EDT 2015
TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.
PloS one
Tsukumo Y,Tsukahara S,Furuno A,Iemura S,Natsume T,Tomida A
Mon Jul 06 00:00:00 EDT 2015
Expression of ATF4 and VEGF in chorionic villus tissue in early spontaneous abortion.
European journal of obstetrics, gynecology, and reproductive biology
Chai L,Ling K,He X,Yang R
Tue Oct 01 00:00:00 EDT 2013
Expression of ATF4 and VEGF in chorionic villus tissue in early spontaneous abortion.
European journal of obstetrics, gynecology, and reproductive biology
Chai L,Ling K,He X,Yang R
Tue Oct 01 00:00:00 EDT 2013
Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.
PloS one
Devi L,Ohno M
Tue Aug 05 00:00:00 EDT 2014
Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.
PloS one
Devi L,Ohno M
Tue Aug 05 00:00:00 EDT 2014
Sinulariolide induced hepatocellular carcinoma apoptosis through activation of mitochondrial-related apoptotic and PERK/eIF2α/ATF4/CHOP pathway.
Molecules (Basel, Switzerland)
Chen YJ,Su JH,Tsao CY,Hung CT,Chao HH,Lin JJ,Liao MH,Yang ZY,Huang HH,Tsai FJ,Weng SH,Wu YJ
Thu Aug 22 00:00:00 EDT 2013
Sinulariolide induced hepatocellular carcinoma apoptosis through activation of mitochondrial-related apoptotic and PERK/eIF2α/ATF4/CHOP pathway.
Molecules (Basel, Switzerland)
Chen YJ,Su JH,Tsao CY,Hung CT,Chao HH,Lin JJ,Liao MH,Yang ZY,Huang HH,Tsai FJ,Weng SH,Wu YJ
Thu Aug 22 00:00:00 EDT 2013
Permissive role of miR-663 in induction of VEGF and activation of the ATF4 branch of unfolded protein response in endothelial cells by oxidized phospholipids.
Atherosclerosis
Afonyushkin T,Oskolkova OV,Bochkov VN
Thu Nov 01 00:00:00 EDT 2012
Permissive role of miR-663 in induction of VEGF and activation of the ATF4 branch of unfolded protein response in endothelial cells by oxidized phospholipids.
Atherosclerosis
Afonyushkin T,Oskolkova OV,Bochkov VN
Thu Nov 01 00:00:00 EDT 2012
TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expression.
Journal of neuroscience research
Suzuki H,Matsuoka M
Thu Mar 01 00:00:00 EST 2012
TDP-43 toxicity is mediated by the unfolded protein response-unrelated induction of C/EBP homologous protein expression.
Journal of neuroscience research
Suzuki H,Matsuoka M
Thu Mar 01 00:00:00 EST 2012
Recombinant Lz-8 from Ganoderma lucidum induces endoplasmic reticulum stress-mediated autophagic cell death in SGC-7901 human gastric cancer cells.
Oncology reports
Liang C,Li H,Zhou H,Zhang S,Liu Z,Zhou Q,Sun F
Sun Apr 01 00:00:00 EDT 2012
Recombinant Lz-8 from Ganoderma lucidum induces endoplasmic reticulum stress-mediated autophagic cell death in SGC-7901 human gastric cancer cells.
Oncology reports
Liang C,Li H,Zhou H,Zhang S,Liu Z,Zhou Q,Sun F
Sun Apr 01 00:00:00 EDT 2012
Proteomic profiling of the 11-dehydrosinulariolide-treated oral carcinoma cells Ca9-22: effects on the cell apoptosis through mitochondrial-related and ER stress pathway.
Journal of proteomics
Liu CI,Wang RY,Lin JJ,Su JH,Chiu CC,Chen JC,Chen JY,Wu YJ
Mon Oct 22 00:00:00 EDT 2012
Proteomic profiling of the 11-dehydrosinulariolide-treated oral carcinoma cells Ca9-22: effects on the cell apoptosis through mitochondrial-related and ER stress pathway.
Journal of proteomics
Liu CI,Wang RY,Lin JJ,Su JH,Chiu CC,Chen JC,Chen JY,Wu YJ
Mon Oct 22 00:00:00 EDT 2012
Compound C prevents the unfolded protein response during glucose deprivation through a mechanism independent of AMPK and BMP signaling.
PloS one
Saito S,Furuno A,Sakurai J,Park HR,Shin-ya K,Tomida A
Thu Feb 28 00:00:00 EST 2013
Compound C prevents the unfolded protein response during glucose deprivation through a mechanism independent of AMPK and BMP signaling.
PloS one
Saito S,Furuno A,Sakurai J,Park HR,Shin-ya K,Tomida A
Thu Feb 28 00:00:00 EST 2013
Role of ER stress response in photodynamic therapy: ROS generated in different subcellular compartments trigger diverse cell death pathways.
PloS one
Moserova I,Kralova J
Mon Jul 09 00:00:00 EDT 2012
Role of ER stress response in photodynamic therapy: ROS generated in different subcellular compartments trigger diverse cell death pathways.
PloS one
Moserova I,Kralova J
Mon Jul 09 00:00:00 EDT 2012
Induction of apoptosis by 11-dehydrosinulariolide via mitochondrial dysregulation and ER stress pathways in human melanoma cells.
Marine drugs
Su TR,Tsai FJ,Lin JJ,Huang HH,Chiu CC,Su JH,Yang YT,Chen JY,Wong BS,Wu YJ
Wed Aug 01 00:00:00 EDT 2012
Induction of apoptosis by 11-dehydrosinulariolide via mitochondrial dysregulation and ER stress pathways in human melanoma cells.
Marine drugs
Su TR,Tsai FJ,Lin JJ,Huang HH,Chiu CC,Su JH,Yang YT,Chen JY,Wong BS,Wu YJ
Wed Aug 01 00:00:00 EDT 2012
Doxorubicin bypasses the cytoprotective effects of eIF2α phosphorylation and promotes PKR-mediated cell death.
Cell death and differentiation
Peidis P,Papadakis AI,Muaddi H,Richard S,Koromilas AE
Sat Jan 01 00:00:00 EST 2011
Doxorubicin bypasses the cytoprotective effects of eIF2α phosphorylation and promotes PKR-mediated cell death.
Cell death and differentiation
Peidis P,Papadakis AI,Muaddi H,Richard S,Koromilas AE
Sat Jan 01 00:00:00 EST 2011
Akt determines cell fate through inhibition of the PERK-eIF2α phosphorylation pathway.
Science signaling
Mounir Z,Krishnamoorthy JL,Wang S,Papadopoulou B,Campbell S,Muller WJ,Hatzoglou M,Koromilas AE
Tue Sep 27 00:00:00 EDT 2011
Akt determines cell fate through inhibition of the PERK-eIF2α phosphorylation pathway.
Science signaling
Mounir Z,Krishnamoorthy JL,Wang S,Papadopoulou B,Campbell S,Muller WJ,Hatzoglou M,Koromilas AE
Tue Sep 27 00:00:00 EDT 2011
Measuring ER stress and the unfolded protein response using mammalian tissue culture system.
Methods in enzymology
Oslowski CM,Urano F
Mon Apr 18 00:00:00 EDT 2011
eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Jiang Z,Belforte JE,Lu Y,Yabe Y,Pickel J,Smith CB,Je HS,Lu B,Nakazawa K
Wed Feb 17 00:00:00 EST 2010
eIF2alpha Phosphorylation-dependent translation in CA1 pyramidal cells impairs hippocampal memory consolidation without affecting general translation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Jiang Z,Belforte JE,Lu Y,Yabe Y,Pickel J,Smith CB,Je HS,Lu B,Nakazawa K
Wed Feb 17 00:00:00 EST 2010
Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.
Molecular biology of the cell
Muaddi H,Majumder M,Peidis P,Papadakis AI,Holcik M,Scheuner D,Kaufman RJ,Hatzoglou M,Koromilas AE
Wed Sep 15 00:00:00 EDT 2010
Phosphorylation of eIF2α at serine 51 is an important determinant of cell survival and adaptation to glucose deficiency.
Molecular biology of the cell
Muaddi H,Majumder M,Peidis P,Papadakis AI,Holcik M,Scheuner D,Kaufman RJ,Hatzoglou M,Koromilas AE
Wed Sep 15 00:00:00 EDT 2010
Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress.
American journal of physiology. Renal physiology
Kawakami T,Inagi R,Wada T,Tanaka T,Fujita T,Nangaku M
Wed Sep 01 00:00:00 EDT 2010
Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress.
American journal of physiology. Renal physiology
Kawakami T,Inagi R,Wada T,Tanaka T,Fujita T,Nangaku M
Wed Sep 01 00:00:00 EDT 2010
Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice.
The Journal of cell biology
Wang X,Rao RP,Kosakowska-Cholody T,Masood MA,Southon E,Zhang H,Berthet C,Nagashim K,Veenstra TK,Tessarollo L,Acharya U,Acharya JK
Mon Jan 12 00:00:00 EST 2009
Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice.
The Journal of cell biology
Wang X,Rao RP,Kosakowska-Cholody T,Masood MA,Southon E,Zhang H,Berthet C,Nagashim K,Veenstra TK,Tessarollo L,Acharya U,Acharya JK
Mon Jan 12 00:00:00 EST 2009
