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ATG2A Polyclonal Antibody

ATG2A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ATG2A Antibody (23226-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 23226-1-AP ( ATG2A Antibody) at dilution of 1:50 (under 40x lens).

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Product Details

23226-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Immunoprecipitation (IP)

View 1 publication 1 publication

Peptide Array (Array)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ATG2A Fusion Protein Ag19709 (194-539 aa encoded by BC110650)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.35 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: RVQRLEYCD EAVRDPSQAP PVDVHQPPAF LHKLLQLAGV RLHYEELPAQ EEPPEPPLQI GSCSGYMELM VKLKQNEAFP GPKLEVAGQL GSLHLLLTPR QLQQLQELLS AVSLTDHEGL ADKLNKSRPL GAEDLWLIEQ DLNQQLQAGA VAEPLSPDPL TNPLLNLDNT DLFFSMAGLT SSVASALSEL SLSDVDLASS VRSDMASRRL SAQAHPAGKM APNPLLDTMR PDSLLKMTLG GVTLTLLQTS APSSGPPDLA THFFTEFDAT KDGPFGSRDF HHLRPRFQRA CPCSHVRLTG TAVQLSWELR TGSRGRRTTS MEVHFGQLEV LECLWPRGTS EPEYTEI (194-539 aa encoded by BC110650 )

Target Information

Involved in autophagosome assembly, regulating the size of nascent autophagosomes (PubMed:28561066). Also regulates lipid droplets morphology and distribution within the cell (PubMed:22219374, PubMed:28561066). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

A phosphoinositide signalling pathway mediates rapid lysosomal repair.

Nature

Tan JX,Finkel T

Thu Sep 01 00:00:00 EDT 2022

ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation.

Molecular cell

van Vliet AR,Chiduza GN,Maslen SL,Pye VE,Joshi D,De Tito S,Jefferies HBJ,Christodoulou E,Roustan C,Punch E,Hervás JH,O'Reilly N,Skehel JM,Cherepanov P,Tooze SA

Thu Nov 17 00:00:00 EST 2022

ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation.

Molecular cell

van Vliet AR,Chiduza GN,Maslen SL,Pye VE,Joshi D,De Tito S,Jefferies HBJ,Christodoulou E,Roustan C,Punch E,Hervás JH,O'Reilly N,Skehel JM,Cherepanov P,Tooze SA

Thu Nov 17 00:00:00 EST 2022

ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation.

Molecular cell

van Vliet AR,Chiduza GN,Maslen SL,Pye VE,Joshi D,De Tito S,Jefferies HBJ,Christodoulou E,Roustan C,Punch E,Hervás JH,O'Reilly N,Skehel JM,Cherepanov P,Tooze SA

Thu Nov 17 00:00:00 EST 2022

ATG9A protects the plasma membrane from programmed and incidental permeabilization.

Nature cell biology

Claude-Taupin A,Jia J,Bhujabal Z,Garfa-Traoré M,Kumar S,da Silva GPD,Javed R,Gu Y,Allers L,Peters R,Wang F,da Costa LJ,Pallikkuth S,Lidke KA,Mauthe M,Verlhac P,Uchiyama Y,Salemi M,Phinney B,Tooze SA,Mari MC,Johansen T,Reggiori F,Deretic V

Sun Aug 01 00:00:00 EDT 2021

The autophagy protein ATG9A enables lipid mobilization from lipid droplets.

Nature communications

Mailler E,Guardia CM,Bai X,Jarnik M,Williamson CD,Li Y,Maio N,Golden A,Bonifacino JS

Fri Nov 19 00:00:00 EST 2021

Fine particulate matter inhibits phagocytosis of macrophages by disturbing autophagy.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Li Y,Yong YL,Yang M,Wang W,Qu X,Dang X,Shang D,Shao Y,Liu J,Chang Y

Tue Dec 01 00:00:00 EST 2020

The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.

Theranostics

Sun W,Li J,Zhou L,Han J,Liu R,Zhang H,Ning T,Gao Z,Liu B,Chen X,Ba Y

Wed Apr 14 00:00:00 EDT 2021

A conserved ATG2-GABARAP family interaction is critical for phagophore formation.

EMBO reports

Bozic M,van den Bekerom L,Milne BA,Goodman N,Roberston L,Prescott AR,Macartney TJ,Dawe N,McEwan DG

Wed Mar 04 00:00:00 EST 2020

A conserved ATG2-GABARAP family interaction is critical for phagophore formation.

EMBO reports

Bozic M,van den Bekerom L,Milne BA,Goodman N,Roberston L,Prescott AR,Macartney TJ,Dawe N,McEwan DG

Wed Mar 04 00:00:00 EST 2020

Bioinformatics

Protein Aliases: ATG2 autophagy related 2 homolog A; Autophagy-related protein 2 homolog A

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Gene Aliases: ATG2A; KIAA0404

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UniProt ID: (Human) Q2TAZ0

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Entrez Gene ID: (Human) 23130

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Function(s)

protein binding

Process(es)

autophagosome assembly mitophagy nucleophagy

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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ATG2A Polyclonal Antibody

ATG2A Antibody (23226-1-AP) in IHC (P)

Product Details

23226-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Peptide Array (Array)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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