Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
ATP Synthase beta Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
ATP Synthase beta Antibody (PA5-81952)
Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. A-549 cells were transfected with, control siRNA, ATP Synthase beta siRNA probe #1, and ATP Synthase beta siRNA probe #2 and a decrease in signal intensity was observed in Western Blot application using anti-ATP Synthase beta Polyclonal Antibody (Product # PA5-81952) used at a dilution of 0.4 µg/mL. Anti-ATP5B was used as a... View More
Product Details
PA5-81952
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ATP5B. Recombinant protein control fragment (Product #RP-100511).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789113
Product Specific Information
Immunogen sequence: LTGLTVAEYF RDQEGQDVLL FIDNIFRFTQ AGSEVSALLG RIPSAVGYQP TLATDMGTMQ ERITTTKKGS ITSVQAIYVP ADDLTDPAPA TTFAHLDATT VLSRAIAELG IYPAVDPLDS TSRIMDPNIV GSEHYDVAR
Target Information
ATP synthase is extremely conserved through evolution and can be found in plants, fungi, bacteria, and animals. The ATP synthase enzyme is a transmembrane protein responsible for driving the reversible reaction from ADP+ phosphate to ATP. This reaction is accomplished by a flux of protons across the membrane as a result of electron transfer. The ATP synthase protein has two main sections; the F1 ATP-ase (soluble) and the F0 ATP-ase (membrane embedded). The F1 section consists of the alpha, beta, gamma, delta, and epsilon subunits. While the F0 consists of a, b, and c subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ATP synthase F1 subunit beta; ATP synthase subunit beta, mitochondrial; ATP synthase, H+ transporting mitochondrial F1 complex, alpha subunit; ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit; epididymis secretory protein Li 271; MGC5231; mitochondrial ATP synthase beta subunit; mitochondrial ATP synthase, H+ transporting F1 complex beta subunit; mitochondrial ATP synthetase, beta subunit
Gene Aliases: ATP5B; ATP5F1B; ATPMB; ATPSB; HEL-S-271
UniProt ID: (Human) P06576, (Rat) P10719, (Mouse) P56480
Entrez Gene ID: (Human) 506, (Rat) 171374, (Mouse) 11947
transporter activity
protein binding
ATP binding
ATPase activity
transmembrane transporter activity
MHC class I protein binding
proton-transporting ATP synthase activity, rotational mechanism
proton-transporting ATPase activity, rotational mechanism
calcium ion binding
lipoprotein particle receptor activity
nucleotide binding
hydrolase activity
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
ATP synthase
angiogenesis
osteoblast differentiation
generation of precursor metabolites and energy
lipid metabolic process
ATP biosynthetic process
negative regulation of cell adhesion involved in substrate-bound cell migration
mitochondrion organization
ATP hydrolysis coupled proton transport
proton transport
mitochondrial ATP synthesis coupled proton transport
regulation of intracellular pH
receptor-mediated endocytosis
ATP synthesis coupled proton transport
ATP metabolic process
transport
ion transport
hydrogen ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support